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837 articles for “Clinical”
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Impact of Diet and Certain Functional Foods in Type-II Diabetes Management
Abstract: Global health is greatly challenged by type 2 diabetes mellitus (T2DM), whose management mostly depends on dietary and lifestyle changes. This review study looks at how important diet and certain functional items are for managing type 2 diabetes. It offers a thorough summary of current scientific discoveries and clinical investigations that emphasize the contribution of dietary decisions and functional foods to better glycemic control, increased insulin sensitivity, and decreased risk …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 1, 2024 · pp. 9–15 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Current Drugs Target the EGFR
Abstract: Cancer is a devastating disease, but there have recently been significant advancements in therapy that have identified EGFR and its related proteins as valuable indicators and targets for treatment. The ERBB receptor tyrosine kinase superfamily includes EGFR, which is a transmembrane glycoprotein. When the EGFR receptor interacts to its particular ligand, EGF, it causes tyrosine residues to be phosphorylated and forms receptor dimers with other members of the receptor family. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 1–8 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Comparative Assessment of Antibacterial Effectiveness, Bioactivity, Fluoride Release, and Microleakage of Various Bioactive Smart Composites: An In Vitro Investigation.
Abstract: The demand for dental composites with enhanced properties has led to the development of bioactive smart composites aimed at addressing multiple aspects of restorative dentistry. This in vitro investigation aimed to conduct a comparative assessment of the antibacterial effectiveness, bioactivity, fluoride release, and microleakage properties of various bioactive smart composites. Bioactive smart composites are emerging dental materials designed to promote remineralization and inhibit bacterial growth, thereby enhancing the longevity of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 76–86 Read article
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Panfacial Trauma- A Case Report
Abstract: The majority of panfacial fractures are accompanied by concurrent organ damage. Panfacial fracture management is difficult and necessitates careful planning, sequencing, and sufficient understanding of the anatomy and management of the condition. In any trauma situation, the ABCDEs (airway, breathing, circulation, disability, and exposure) always remain the primary care priorities. Maxillofacial surgeons are essential in the early stabilization of fractures, the management of localized bleeding into the face, and the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 21–25 Read article
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Development and Fabrication of Biohydrogel for Targeted Delivery of Delafloxacin for Bacterial Skin Infections
Abstract: The escalating challenge of bacterial resistance necessitates innovative drug delivery systems to enhance the efficacy of antibiotics. This study focuses on the development and optimization of a biohydrogel formulation for the targeted delivery of Delafloxacin, aiming to improve its therapeutic outcomes against resistant bacterial strains. Utilizing a 3² factorial design, biohydrogel formulations incorporating Poly(N-isopropylacrylamide) (PNIPAM) and Genipin were synthesized. The optimization process was guided by Design Expert software, focusing on …
Published in Research & Reviews: A Journal of Drug Design & Discovery Read article
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A review on scope and use of Robots in healthcare sector in Kerala and related ethical issues
Abstract: In today’s rapidly evolving world, robots have become integral to various industries, including healthcare. Their precision, efficiency, and ability to perform repetitive tasks have transformed patient care and clinical procedures. While developed countries have embraced robotic technologies, India, particularly Kerala, is still in the early stages of integrating robots into healthcare. Surgical assistance and patient rehabilitation are key use cases. However, this adoption raises ethical, privacy, and regulatory concerns. As …
Published in Journal of Production Research & Management Read article
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Ayurvedic Approach in Case of Irritable Bowel Disease– A Case Study Highlighting the Efficacy and Safety
Abstract: Irritable bowel disease (IBD) is a common psychosomatic disorder that affects the gastrointestinal system, with symptoms that include cramping, abdominal pain, bloating, flatulence, and diarrhea or constipation, or both. If left untreated, it turns into chronic IBS. It can be controlled by adjusting the diet, changing the lifestyle. More severe symptoms include weight loss, diarrhea at night, bleeding from the rectum, anemia due to iron deficiency, unexplained vomiting, and pain …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 9–13 Read article
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Role of Topical Onion Extract in Scar Management at Donor Site
Abstract: Scarring is commonly caused by an imbalance between collagen synthesis and degradation. One promising approach to mitigate scar formation involves the use of onion extract, known for its ability to inhibit fibroblast activity, which plays a key role in the development of scars. Despite the widespread use of onion extract in various commercial scar treatment products, the exact molecular mechanisms through which it exerts its scar-reducing effects remain unclear.This study …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 7–11 Read article
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Effect of Vamanadhauti Along with Diet and Lifestyle Modification as per Ayurveda in Ajeerna w.s.r. Dyspepsia–A Case Study
Abstract: Introduction: In present era, Ajeerna is a very common health issue and has resemblance with dyspepsia. Ajeerna denotes improper functioning of Agni leading to lots of other diseases. Unhealthy & sedentary lifestyle, increasing intake of fast food and faulty eating habits play important role in pathogenesis of Ajeerna. In the context of Ajeerna, Sadyovamana Chikitsa is described which can be correlated with a Yogic cleansing procedure-Vamanadhauti. Vamanadhauti mainly acts on …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 24–35 Read article
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A Review on Ethnomedicinal Claims of Gloriosa Superba Linn. (Langali).
Abstract: Aim: Gloriosa superba Linn., is a procumbent herbaceous climber and different parts of G. superba, have wide diversity of uses especially in traditional system of medicine among local healers. The goal of the current review is to gather information on research updates and claims pertaining to ethno medicine and folklore that is currently accessible. Material and Methods: Information and data regarding reported ethno medicinal uses and folklore claims of the …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 14–23 Read article
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Machine Learning Approaches in Breast Cancer Diagnosis: Current Trends and Future Perspectives
Abstract: Since cancer is still one of the world's top causes of death, precise and effective detection techniques must be developed. Machine learning (ML) approaches have shown promise in recent years for enhancing cancer prognosis and detection. This paper presents a comprehensive review of the application of ML in cancer detection, focusing on various modalities including medical imaging, genomic data, and clinical records. We highlight the challenges associated with traditional cancer …
Published in International Journal of Radio Frequency Innovations · Vol. 2, Issue 1, 2024 · pp. 14–20 Read article
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Trauma- Its Transgenerational Inheritance and Associated Nuances in Perinatal Care: A Systematic Review
Abstract: The research is a systematic review of the existing clinical and animal studies pertaining to effects of trauma on immediate offsprings and its transgenerational inheritance. The research also summarises the current statistical data on perinatal care globally with special emphasis on India as a developing nation and the current strategies, government policies and international recommendations on maternal and child health as put forward in the Sustainable development goal 2030 by …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 37–45 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Bacterial Spectral in UTI in a Hospital Environment
Abstract: Urinary tract infections (UTIs) represent a significant public health issue, primarily caused by a variety of pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. UTIs contribute substantially to illness and complications in individuals with pre-existing health conditions and account for a large portion of hospital visits globally. UTIs are usually self-limiting in people with no structural or functional problems, but they do tend to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Metabolites in Modern Medicine: Decoding the Future of Health and Diseases
Abstract: The end products of many metabolic processes in cells are called metabolites. Each reaction contributes a specific metabolite. Metabolites act as fingerprints of on-going biological processes. Constant changes in cellular composition due to both environmental and internal factors. By analysing the types and presence of metabolites, scientists can effectively reconstruct the inner workings of a cell or organism. In the past, analysing metabolites was a slow and tedious process, often …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 1–13 Read article
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Advancements in AI-Driven Diagnostics for Dental Health: A Comprehensive Review
Abstract: Dental diseases, also known as oral diseases or dental conditions, encompass a range of health problems affecting the teeth, gums, mouth, and associated structures. These conditions can lead to pain, discomfort, and severe complications if left untreated. Early detection and accurate diagnosis are crucial for effective treatment and prevention of further complications. This comprehensive literature review aims to identify common dental problems such as Tooth Decay (Cavities), Gingivitis, Periodontitis, and …
Published in Current Trends in Signal Processing · Vol. 14, Issue 2, 2024 · pp. 1–7 Read article
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Nerve Damage and Its Remedies
Abstract: Fringe Nerve Wounds are one of the most well-known reasons for hand brokenness brought about by upper appendage injury yet current administration has remained sub-standard. This survey means to make sense of the conventional perspective on pathophysiology of nerve fix and furthermore portray why careful administration is as yet lacking in utilizing the new natural research that has recorded the progressions that happen after the nerve injury, which, could cause …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 7–14 Read article
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Early Autism Diagnosis: Machine Learning Models and Their Effectiveness
Abstract: Diagnosis is of utmost importance for timely intervention and support. However, traditional diagnosis methods, which are based on subjective assessment, are delayed. This project explores the role that machine learning techniques might play in enhancing the accuracy and effectiveness of ASD detection. Several state-of-the-art classification algorithms were benchmarked using a dataset from Kaggle. Logistic Regression, XG Boost, Random Forest, Decision Tree, and Gradient Boosting were taken into consideration. Other performance …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 2, 2024 Read article