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474 articles for “Clinical study”
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Assessment of Women's Knowledge of Mastitis at Indus International Hospital, Punjab
Abstract: Mastitis is a non-cancerous inflammatory condition of the breast, often resulting from infection, which can impact the mammary gland's structures. It is a relatively frequent condition, affecting between 5% and 33% of women during lactation at some point in their lives. Typical clinical signs include pain in one breast, redness (erythema), and swelling, often accompanied by flu-like symptoms such as fever, chills, and body aches. Upon examination, the affected breast …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 3, 2024 Read article
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Neuroprotective Effects of Curcuma longa: A Review of Its Role in Neurodegenerative Diseases
Abstract: Curcuma longa (turmeric), a perennial herb notably utilized in traditional medication, has garnered big clinical attention due to its major bioactive compound, curcumin. Curcumin, well-known shows a couple of organic activities, together with antioxidant, anti-amyloidogenic, and neurodegenerative effects, making it a promising candidate for the management of neurodegenerative diseases (NDDs), which include Alzheimer’s illness, Parkinson’s disorder (PD), Huntington’s sickness (HD), and amyotrophic lateral sclerosis (ALS). This evaluate consolidates current findings …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 24–32 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Pharma Guard: Smart Medication Management System
Abstract: Pharma Guard Smart Medication Management System presenting a comprehensive overview of an innovative technology designed to revolutionize medication management in healthcare settings. In an era of advancing digital solutions, the Pharma Guard system offers a sophisticated approach to ensuring medication safety and adherence. Through the integration of smart technology, including internet of things (IoT) devices and machine learning algorithms, Pharma Guard enables real-time monitoring, tracking, and management of medication consumption …
Published in International Journal of Mobile Computing Technology · Vol. 2, Issue 1, 2024 · pp. 30–37 Read article
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Role of Centella asiatica in Alzheimer’s Disease: A Comprehensive Review
Abstract: Alzheimer's disease (AD) is a progressive neurological illness that causes cognitive decline and memory loss and affects millions of people worldwide. As synthetic medications often prove ineffective or cause severe side effects, natural remedies are gaining attention. This review explores the potential of Centella asiatica, a herb traditionally used in oriental medicine, in the treatment of Alzheimer's disease. Triterpenoids, asiaticoside, and madecassoside are among the bioactive substances found in Centella …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Microwave Signals: A New Frontier in Non-Invasive Medical Diagnostics: A Study
Abstract: Imagine a future where medical diagnoses are quicker, safer, and more accessible, and where therapies are more precise and less invasive. This future is rapidly approaching, driven in part by the quiet revolution of microwave signals in medicine. Far from their everyday use in ovens and communication, these non-ionizing electromagnetic waves are proving to be powerful tools, offering unprecedented insights into the human body and innovative ways to treat disease. …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 3, 2025 · pp. 27–41 Read article
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Modernizing Pharmacovigilance: Leveraging AI, Automation, and Real-World Data for Drug Safety
Abstract: Pharmacovigilance, or PV, is “the pharmacological science relating to the detection, assessment, understanding, and prevention of adverse effects, mainly long term and short-term adverse effects of medicines.” PV’s specific objectives are to increase patient care and safety when using medications and all medical and paramedical therapies; assist in evaluating the benefits, drawbacks, efficacy, and risks of medications, ensuring their safe, prudent, and more effective use; and promote clinical training, education, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 12–21 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Artificial Intelligence for Improved Healthcare: A Case Study and Applications
Abstract: Artificial intelligence (AI) in healthcare ushers in a revolutionary period of innovation, but it also brings with it significant ethical dilemmas. This paper explores the complex relationship between AI and healthcare, emphasizing both its useful applications and the moral conundrums that arise. Ethical issues span a wide range, including patient privacy, transparency, accountability, and the unintentional reinforcement of biases in AI algorithms. Privacy concerns take center stage as healthcare providers …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 1–12 Read article
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Unresolved and misdiagnosed of floating sensation in young man
Abstract: Persistent Postural-Perceptual Dizziness (PPPD) stands out as a prevalent peripheral vestibular disorder, earning its recognition in the International Classification of Vestibular Disorders in 2017. Characterized by chronicity, this condition manifests symptoms persisting for more than three months, encompassing a disconcerting array such as a floating sensation, unsteadiness, and dizziness. Notably, individuals afflicted with PPPD often report symptom exacerbation following prolonged standing, self-initiated motion, or exposure to dynamic visual stimuli. This …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 1–4 Read article
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Evaluation Of the Quality of Sleep in Healthy Individuals Based on Practice of (CYP)- A Pilot Study.
Abstract: Introduction-Sleep is basic requirement of all living beings. Specially, in human beings it is considered as one of the supportive factor of existence. Ahara(food), Nidra(sleep) and Bramhacharya(righteous conduct/celibacy) are the three factors explained in classical texts as Traya Upastambha(Tripods). Not only Ayurveda literatures, its description and importance is available in Upanishads too. Mandukya Upanishad has allotted a full chapter on sleep and consciousness. But, as the era has entered into …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 40–47 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Systematic Analysis of the Pharmacological Properties of Different Plant Parts of Madhuca sp.
Abstract: Madhuca sp., a perennial tree belonging to the Sapotaceae family, are widely distributed across South and Southeast Asia. It holds considerable value across the food, beverage, and pharmaceutical sectors. The growing interest among cultivators, agronomists, and industry stakeholders stems from the diverse bioactive potential documented across different parts of the plant, including the bark, leaves, seeds, and flowers. Traditional and emerging evidence points to a wide spectrum of pharmacological actions, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 Read article
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Role of Low Level Laser Therapy (LLLT) in Healing of Electric Burns
Abstract: The objective of this case study is to evaluate the effectiveness of low-level laser therapy (LLLT) in treating scalp wounds caused by electric burns. A thorough examination of the scalp wound was conducted both before and after administering LLLT. The findings suggest that LLLT plays a beneficial role in the healing process of superficial ulcers. Specifically, the application of LLLT (as depicted in Figure 1) demonstrated promising results in facilitating …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 39–44 Read article
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Effect of Vamanadhauti Along with Diet and Lifestyle Modification as per Ayurveda in Ajeerna w.s.r. Dyspepsia–A Case Study
Abstract: Introduction: In present era, Ajeerna is a very common health issue and has resemblance with dyspepsia. Ajeerna denotes improper functioning of Agni leading to lots of other diseases. Unhealthy & sedentary lifestyle, increasing intake of fast food and faulty eating habits play important role in pathogenesis of Ajeerna. In the context of Ajeerna, Sadyovamana Chikitsa is described which can be correlated with a Yogic cleansing procedure-Vamanadhauti. Vamanadhauti mainly acts on …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 24–35 Read article
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Comprehensive Approaches to Seizure Control: Home Care & Hospital Care
Abstract: Seizures show up as sudden, uncontrollable brain electrical abnormalities. Those afflicted by this health issue can suffer greatly and usually call for quick and thorough treatment. Examining several facets of seizure control, including disease epidemiology, etiology, clinical presentation, categorization, as well as acute and long-term therapy techniques, this review. Furthermore, emphasized in the review are several new trends that might help with seizure control. Factors including CNS infections, metabolic abnormalities, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 30–34 Read article
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A Study to Assess the Effectiveness of Home-based Stretching Exercises on Joint Pain Among Clients with Osteoarthritis in Selected Old Age Home, Rajkot City, Gujarat
Abstract: Osteoarthritis (OA) is a commonly encountered condition in middle-aged and older individuals, marked by its slow development. Strengthening exercises targeting the quadriceps muscles, situated in the front thigh, can mitigate knee pain, and reduce disability associated with OA. The musculoskeletal system encompasses the bones of the skeleton, the joints where these bones connect, and the muscles responsible for enabling and regulating movement. The knee, the largest and most complex joint, …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 24–28 Read article
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Artificial Intelligence based Point of Care Device in Advanced Medical Diagnostic Techniques
Abstract: Application of Point-of-Care Testing (POCT) at medical sites provides instant diagnostic results that help doctors make quick decisions for patient care. The traditional point-of-care testing equipment faces restrictions because they test single parameters and experience calibration problems in addition to inefficient data management systems. POCT technology benefits from the integration of Artificial Intelligence (AI) which creates a novel system to solve current operational limitations. The presented study introduces an intelligent …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article