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240 articles for “targeted delivery”
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Biodegradable Polymer Nano Composites for Enhanced Drug Bioavailability
Abstract: Polymer-based nanoparticles have emerged as a revolutionary approach in drug delivery systems, particularly in enhancing the bioavailability of poorly soluble and unstable drugs. These nanoparticles, composed of both natural and synthetic polymers, serve as effective vehicles for encapsulating a wide range of therapeutic agents. Their surface characteristics can also be modified to enable targeted drug delivery, increasing the concentration of drugs at the site of action while minimizing side effects. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 433–443 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Development of Polymersomes as Macromolecular Platforms for Nanomedicine
Abstract: The conventional method of drug delivery is plagued with instability, low targeting and low bioavailability. A solution to these shortcomings is the use of polymersomes, artificial vesicles that are produced through self-assembly of amphiphilic block copolymer, and they are suggested as universal nanoscale carriers. They have stiff, tunable membranes (thickness = 2–50 nm) due to accurate control of polymer chemistry, chain length, and hydrophilic mass fraction (f), which allows predictability …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 71–89 Read article
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Nanotechnology: Recent Advances, Opportunities and Challenges
Abstract: Nanotechnology, the science of the minuscule, has catalysed a revolution across diverse fields, from pharmacy to veterinary science. This abstract encapsulates the dynamic interplay between nanotechnology and healthcare, unveiling its transformative impact on drug delivery, cosmeceuticals, veterinary medicine, dentistry, and biotechnology. In pharmacy, nanotechnology pioneers targeted drug delivery systems, amplifying therapeutic efficacy while mitigating adverse effects. Nano-cosmeceuticals redefine beauty standards, infusing skincare, haircare, lip care, and nail care products with …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 44–64 Read article
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Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
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Innovative 3D Printed Cell Scaffolds with Magnetized Nanocomposites for Targeted Cancer Therapy Drug Delivery
Abstract: In recent years, scaffolds have gained increasing attention in the field of tissue engineering, especially in cancer treatment. Nanocomposite scaffolds have emerged as promising candidates for delivering drugs to cancer cells. 3D printing technology has enabled the fabrication of customized scaffolds with precise pore size and complex geometries. This study explores the development of 3D printed scaffolds of nanostructured made of graphene oxide and Poly-Caprolactone (PCL) nanocomposites, which can be …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 48–55 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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A Review of basic Concept of Specific Drug Delivery System
Abstract: ABSTRACTThis review focus going on targeted drug delivery via Nanoparticles as a Special composition that couple a receptor site to a Nanosized , drug-loaded transporter as a budding means to get improved effectiveness of a drug at the site of significance. The conception of targeted drugs is not new, but since to 1906 while Ehrlich initial postulate the ‘magic bullet’. therefore is must to build up a appropriate drug system …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 21–26 Read article
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Nanotechnology-Driven Drug Delivery: A Comprehensive Review of Current Trends and Future Directions
Abstract: Nanotechnology has revolutionized drug delivery systems, offering profound advancements in precision, efficiency, and targeted therapeutic interventions. This review examines the revolutionary influence of nanotechnology on medical therapies, focusing on advancements, such as precise drug delivery, improved solubility, and responsive treatment systems. These advancements have significantly improved treatment efficacy and minimize side effects, particularly in oncology and chronic disease management. The development of nanoparticles designed for specific cell targeting and environmental …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 24–46 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Stimuli-Responsive Polymers for Drug Release in Targeted Therapy
Abstract: SRPs, or stimuli-responsive polymers, are becoming a good way to give specific drugs. They let medicines be released in a controlled way. Some of the things that can change these polymers are pH, temperature, light, magnetic fields, and the number of ions present. Some outside signs can make SRPs respond, which helps control how drugs are released. This cuts down on side effects and improves the effectiveness of focused treatments. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 252–265 Read article
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Graphene Oxide: A Potential Drug Carrier for Cancer Therapy—Review
Abstract: Graphene oxide (GO) is a single or few layer’s sheet derived from graphite using strong oxidizing agents. Graphene oxide possesses outstanding aqueous processability, amphiphilicity, functionalizability, surface enhanced area and fluorescence ability. Hydrophilicity is an important property for mixing the material with ceramic or polymer matrixes while trying to improve their electrical and mechanical properties. Acquiring a promising application in the biomedical area, graphene molecules undergo complex interactions with the biological …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 21–31 Read article
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APPLICATIONS OF NANOTECHNOLOGY IN CROP IMPROVEMENT: NEW ERA OF AGRICULTURE
Abstract: It represents a transformative force in agriculture, promising to improve the productivity, yield, sustainability, and food security. This review paper focused on the certain advantages of nanoscience and nanotechnology in enhancing the agricultural productivity, disease management, and food safety. By manipulating different materials and objects at the nanoscale, researchers can develop advanced tools such as smart sensors and targeted delivery systems that improve nutrient absorption and combat plant pathogens. By …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 46–54 Read article
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Nanomedicine in the Tumor Microenvironment: Physiological Modulation Through Tissue Engineering Approaches
Abstract: The integration of nanomedicine and tissue engineering offers transformative strategies for cancer therapy by directly modulating the physiological processes within the tumor microenvironment (TME). This review emphasizes recent advances in nanomedicine that enable precise drug delivery, controlled release, and real-time monitoring of key physiological parameters influencing tumor progression, angiogenesis, and immune evasion. Tissue-engineered 3D tumor models provide physiologically relevant platforms that better mimic in vivo conditions than traditional 2D cultures, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 19–31 Read article
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Biodegradable Polymer Nanocarriers Composites for Biomedical Applications
Abstract: Smart polymeric nanocarriers, or SPNs, have evolved into a fascinating means of delivering medications especially to cancer cells. By improving the efficacy of chemotherapeutic treatments while lowering their negative effects, they have achieved a significant progress in exact medicine. Made to respond to certain elements in the tumours microenvironment, such as enzymes, temperature, pH, and redox conditions, these nanocarriers this reaction to triggers guarantees the release of the medicine at …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 293–305 Read article
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A Review on Applications of Nanoparticles in Cancer Treatment
Abstract: Cancer has become the leading cause of death. It is caused by disorder in the division and growth of cells. It can be treated after the confirmation of growth of cancerous cells. Conventionally it is done by x-rays or CT scans. Then the genes are destroyed or damaged or by controlling the blood supply to other genes. Now advancements in nanotechnology have enabled the physicians to treat the cancer. In …
Published in Research & Reviews : Journal of Physics · Vol. 7, Issue 3, 2018 · pp. 31–35 Read article
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A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery
Abstract: Nanotechnology has become a groundbreaking strategy in cancer therapy, especially in drug delivery systems, offering improved treatment effectiveness while minimizing the adverse effects associated with traditional methods. This review presents an in-depth analysis of recent progress in nanotechnology for cancer drug delivery, emphasizing the design, mechanisms, and practical applications of nanoparticle-based systems. Nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, offer unique advantages, including improved drug solubility, targeted delivery to …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 24–33 Read article
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Nano-Materials in Vaccine Formation and Chemical Formulae’s for Vaccination
Abstract: For centuries, vaccines have been a cornerstone of public health, preventing debilitating and deadly diseases. However, the development and delivery of effective vaccines have always been met with challenges. From stability issues and limited immune response to the need for specific targeting, scientists are constantly seeking innovative approaches to improve vaccine efficacy and accessibility. Enter nanomaterials – minuscule materials with dimensions at the nanoscale – offering a powerful toolkit to …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 3, 2025 · pp. 27–39 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article