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38 articles for “reactive oxygen species (ROS)”
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Evaluation of the antioxidants potential and total phenolic contents of the Albbizia siris a drug plant
Abstract: Free radicals are the major problems of the world today. They are formed endogenously as well as exogenously by different kinds of metabolic processes in the body. Some of them are highly toxic process causing considerable damage to the system and produce several kindsof disorders. Antioxidants are the substance which reduces the formation of free radicals inthe body and are responsible for degradation of free radical and reactive oxygen species …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 1, 2019 · pp. 21–25 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Cadmium Toxicity: Oxidative Stress and Organ Dysfunction
Abstract: Due to continued anthropogenic mobilization, cadmium accumulation in the environment causes various health problems because of its diverse toxic effects, extremely lingering biological half life (20–30 years), low rate of excretion from the body and storage predominantly in soft tissue primarily liver and kidney. Cadmium is known to have numerous noxious effects, including nephrotoxicity, hepatoxicity, osteoporosis, cardiovascular toxicity, lung toxicity, and reproductive toxicity. The biologically significant ionic form of cadmium, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 2, 2014 · pp. 14–31 Read article
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Carbon Nanoparticles: Occupational Exposure and Genotoxic Effects
Abstract: The field of nanotechnology is revolutionizing today’s era by being the fastest emerging field. Though nanotechnology is the boon to the society, the potential toxicity of these nanoparticles should not be ignored as they can affect anyone from microbes to humans. The main focus of this paper is the toxicity of nanoparticles because people working in these areas, prone to nanoparticles are at high risk due to its toxic property. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 9–26 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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Green Synthesis and Characterization of Silver Nanoparticle using Leaves of Lawsonia inermis: Antibacterial, Antifungal and Anti-Oxidant Activity
Abstract: Nanotechnology is one of the fastest developing sciences over the past few years. This is an emerging field of modern research dealing with synthesis and designing of particle structure ranging from approximately 1–100 nm. Silver nanoparticles (AgNPs) are known for their tremendous applications in the field of therapeutics and diagnosis. In the present study, we have confirmed that the antibacterial, antifungal and anti-oxidant activity of biosynthesized AgNPs which were synthesized …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 6, Issue 1, 2016 · pp. 11–23 Read article
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Study of Radioactive Productivity in Swiss Albino Mice of Herbal Project by Plant Extract
Abstract: Use of ionising radiation for both peaceful and military purpose has increased the exposure risk to living organisms. Gamma radiation, X-Rays and various isotopes are the most common source of human exposure. Radon products, Nuclear weapons, use of atomic energy in industries, isotopes in the field of medicine institutes of research are the other sources from which man may receive radiation. Ionizing radiations generate reactive oxygen species (ROS) through radiolysis …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 2, Issue 3, 2012 · pp. 20–33 Read article
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Glutathione peroxidase (GPx) in Breast Carcinoma
Abstract: Cancer is one of the significant problem from health perspective, every year many females are diagnosed with breast cancer out of which many die because of this disease worldwide. Oxidative stress in human body is a result of imbalance between free radical production and antioxidant defense which may result in carcinogenesis. Primary defense Primary defenses rely on the direct scavenging and inactivation of the reactive oxygen species (ROS) which includes …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 1–5 Read article
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Superoxide Dismutase (SOD) in Breast Carcinoma
Abstract: Breast cancer is the leading problem around the world predominantly in developing parts. Oxidative stress plays a crucial role in carcinogenesis especially in breast carcinoma. Disbalance in free radical and antioxidants result in oxidative stress. Enzymes like Superoxide dismutase (SOD) are used as primary defence; they directly scavenge and inactivate reactive oxygen species (ROS). Keeping this in mind, this study has been designed to study SOD in breast carcinoma before …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 94–98 Read article
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Superoxide Dismutase: An Emerging Target for Human Therapeutic
Abstract: Superoxide dismutases (SODs) represent a very essential antioxidant guard beside oxidative stress in the body. The enzyme does something as an excellent restorative mediator next to reactive oxygen species (ROSs)-mediated multiple sicknesses. The current review portrays the curative property of SOD in diverse physiological and pathological circumstances such as cancer, inflammatory diseases, gene mutation, cardio therapy, aging, neurodegenerative diseases, and diabetes. However, the enzyme has positive boundaries in experimental applications. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 165–172 Read article
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In vitro/In vivo Study of Anti-inflammatory Effect of Cyperus rotundus on Diabetic Complications
Abstract: The reactive oxygen species (ROS) develop oxidative stress that contributes to the cause of human diseases. Radicals which enhance inflammation are nitric oxide, hydroxyl radical, hydrogen peroxide, and superoxide. Anion mediate and amplify the inflammation process, mediate vascular permeability and platelet aggregation leading to diabetic complications due to disruption of steady state of pro-oxidants and antioxidants. Cyperus rotundus plant extract was subjected to foraging radical activity with hemolysate sample to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 24–32 Read article
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Paradigm Shift of Hair Dye Use from Natural to Synthetic: A Concern for Carcinogenic Trigger
Abstract: More than 60% of the young population in different parts of the world use synthetic hair dyes to enhance their looks. People prefer to use synthetic formulations over natural ones. Synthetic hair dyes consist of potentially toxic and mutagenic chemicals depending upon the class they belong to. These chemicals interact with each other to form pigment molecules. Most of the hair dyes contain aromatic amines and its derivatives to produce …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 11, Issue 3, 2021 · pp. 15–22 Read article
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Oxidative stress analysis of cancer patient treated with Radiotherapy
Abstract: Oxidative stress is a term given to overload of free radicals in the body caused by an imbalance between levels of free radicals and antioxidants in the body. Reactive Oxygen Species (ROS) are free radicals also known as oxygen radicals that are produced by various physiological reactions inside the body leading to increasing oxidative stress that can lead to cell death. In case of cancer management, radiation therapy works by …
Published in Trends in Drug Delivery · Vol. 10, Issue 1, 2023 · pp. 28–31 Read article
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Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
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Factors Responsible for Severity of Malaria
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Malaria causes high mortality and morbidity in the world, and 90% of all cases and 75% of deaths occurs in Africa. This distribution is intimately associated with poverty, topography, climatic condition, and the spread of vector and parasite species. To conduct effective treatment and prevention, the mechanism of pathogenesis of malaria should be recognized adequately, which unfortunately remains unclear and debatable. In …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 5, Issue 2, 2015 · pp. 27–37 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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Review on Histological and Functional Effect of Alcohol on Liver and Kidney
Abstract: Alcohol consumption represents the third largest risk factor for disease burden in most countries of the world. The purpose of this review is to give a comprehensive report of the existing data on the potential adverse effects of alcohol on liver and kidney toxicity. We used 82 different published materials for the compilation of this review article. The Google search engine was used for accessing published materials from databases like …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 49–62 Read article