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337 articles for “genetic study”
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A Correlation of Genetic and Clinical Perspective of Becker’s Muscular Dystrophy
Abstract: Patients from neurogenetic clinic on the basis of clinical features, elevated serum CPK level and electromyographic features were recruited for the study. Molecular genetic testing was performed by Multiplex Polymerase Chain Reaction (PCR) technique. A total of 60 patients were recruited in this study out of which 36 patients had deletion and 24 patients had no deletion. Our data showed that there is no correlation between clinical severity/laboratory findings and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 1, 2019 · pp. 33–37 Read article
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Dynamic Balancing of Four-bar Mechanism Using Genetic Algorithm
Abstract: This study is to optimize the design parameters of planar four-bar mechanism using MINI TAB and Genetic Algorithm approach by minimizing shaking force and shaking moments. Using MATLAB, the position, velocity, acceleration, and forces of each link was determined. A set of weighting factors was selected according to the contribution of x and y components of the forces and moments. The regression equation generated by MINI TAB was used as …
Published in Trends in Machine design · Vol. 8, Issue 2, 2021 · pp. 11–20 Read article
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Genetic Divergence for Yield and Yield Attributes of Spring Rice (Oryza sativa L.) Genotypes in Western Hill of Nepal
Abstract: A varietal trial of spring rice (Oryza sativa L.) was conducted in the farmer field at Dhamilikuwa, Lamjung, Nepal with an objective to study the genetic divergence for yield and yield related components from March 2017-June 2017. The experiment was carried out in randomized complete block design (RCBD) having eighteen genotypes with three replications. Cluster analysis revealed that eighteen genotypes were grouped into four clusters based on Euclidean distance. Cluster …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 7, Issue 2, 2018 · pp. 1–4 Read article
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Pharmacogenomics in Anesthesia: Case Studies and Clinical Applications for Personalized Care
Abstract: Pharmacogenomics, the study of how genetic variability influences individual responses to medications, is transforming anesthetic practice by enabling personalized care. This case study collection explores the integration of pharmacogenomic insights into anesthesia management, highlighting its impact on safety, efficacy, and patient outcomes. Adverse reactions to anesthetics often arise from genetic polymorphisms that alter drug metabolism or sensitivity. For instance, patients with RYR1 mutations are susceptible to malignant hyperthermia (MH) when …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 85–91 Read article
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Behavioural Assessment of Muscle Development by Downregulating Different Types of Integrins in Drosophila melanogaster
Abstract: Muscles play a major role in movement and diverse activities required for survival of an organism. In Drosophila, larval crawling and peristalsis are such kinds of rhythmic movements and are driven by muscle contractions. Larval crawling involves random walk on the solid surface whereas peristalsis involves one full body wall muscle contraction from anterior to posterior or in reverse direction in fluid. Accuracy in the development of muscles is an …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 2, 2018 · pp. 55–63 Read article
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Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article
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The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
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Challenges of Upgrading Local Cattle with Exotic Breeds: Genetic, Environmental, Economic, and Sustainability Trade-offs
Abstract: The practice of upgrading local cattle with exotic breeds has gained popularity as a strategy to enhance milk and meat production. While this approach holds potential for improving productivity, it also presents a range of challenges that need careful consideration. This study examines the genetic, environmental, economic, and sustainability trade-offs associated with upgrading local cattle with exotic breeds. From a genetic perspective, upgrading can result in the dilution of traits …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 · pp. 38–53 Read article
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Cancer biology and Sequencing technology: A new era for personalized patient care.
Abstract: Cancer is one of the most deadly diseases causing high mortality around the world. Lot of efforts are being made to be able to device a proper treatment for cancers. The majority treatments for various types of cancers comprise of surgery, radiation, chemotherapy, hormone therapy, immune therapy, and targeted therapy. These methods of treatment may not be fully able to get rid of cancer but able to extend the life …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 1–14 Read article
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Review of Breeding for Ascochyta Blight [Phoma exigua var. diversispora (Bubak) Boerema] Resistance in Common Bean
Abstract: AbstractBean ascochyta blight, caused by Phoma exigua var. diversispora, is an important disease of the common bean (Phaseolus vulgaris L.) throughout Rwanda. It is known to cause total crop losses, especially under humid conditions and low soil fertility. This review focuses on the taxonomy and agronomy of the common bean. It discusses the origin and diversity of beans, and highlights the production constraints. The review dwells on studies on genetic …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 2, 2017 · pp. 38–53 Read article
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Principal Component Analysis of Black and Brown Seeded Soybean (Glycine max (L.) Merr.) Genotypes at Jimma and Bonga Southwestern Ethiopia
Abstract: Sixty-four soybean genotypes were evaluated for cluster analysis based on their morphological characters. The field experiment was carried out at Jimma and Bonga in south-western Ethiopia during the main cropping season of 2019. The experimental study was laid with simple lattice design with two replications. Data on 11 quantitative agronomic traits were gathered. For all of the examined variables, analysis of variance revealed substantial to very significant variations among genotypes. …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 12, Issue 2, 2023 · pp. 13–17 Read article
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Statistical Models for Predicting Genetic Variability and Disease Susceptibility
Abstract: Differences in genetics are key to understanding why some individuals are more prone to certain diseases than others. Recent advancements in genomic research, combined with statistical modeling techniques, have made significant strides in predicting disease risk based on genetic factors. This review explores the application of statistical models for predicting genetic variability and their role in disease susceptibility. We discuss traditional methods like linear regression and genome-wide association studies (GWAS), …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 30–34 Read article
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Beejdushti: A Conceptual Study
Abstract: The appreciation of genetic factors as arbiters of human disease is a relatively recent development in medical history. Scattered references to inheritance of biological characteristics may be found in the records of several millennia. In which comes the Ayurvedic texts. In Ayurvedic texts the genetic concept of inheritance is beautifully described in Caraka Sharir Sthan. Although Other Authors also described in direct or indirect way the genetic basis of inheritance …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 2, 2015 · pp. 48–53 Read article
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Prevalence of Genetic Predisposition in Patients of Diabetes Mellitus Type-2
Abstract: Diabetes Mellitus Type-2 (DM-2) is a metabolic disease of dreaded consequences. Its prevalence is rising day by day in almost all countries, more so in developing countries. Faulty dietary habits, sedentary lifestyle, and stressors of day to day life are considered as important risk factors for the DM-2. Beside this genetic background also plays an important role towards the susceptibility of diabetes mellitus. In present study 166 diagnosed patients of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 1, Issue 1-3, 2012 · pp. 118–226 Read article
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Genetic Algorithm Based Optimized QoS Routing in MANET
Abstract: Ad hoc wireless network may be a dynamic multi-hop network, which is established by an assembly of mobile nodes on a shared wireless channel. Mobile ad hoc network (MANET) is a collection of independent nodes that communicate with each other by forming a multi hop radio network. The design and analysis of routing protocols is a crucial issue in dynamic networks such as packet radio and ad-hoc wireless networks. While …
Published in Journal of Advances in Shell Programming · Vol. 9, Issue 1, 2022 · pp. 6–14 Read article
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Exploring the Genetic and Environmental Factors Contributing to Ovarian Cancer in Women in Mumbai, India
Abstract: Background: Ovarian cancer incidence in Mumbai has risen by 30% over the past decade, with an age-standardized rate of 9.1 per 100,000 women, contrasting stable trends in Western nations. This study investigates the interplay of genetic and environmental factors driving this disparity in Mumbai’s diverse population. Methods: A hospital-based case-control study was conducted at a hospital, enrolling 200 epithelial ovarian cancer cases (aged 30–70 years) and 400 age-matched controls. Germline …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 12–17 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 · pp. 22–36 Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 · pp. 10–19 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article