Search
232 articles for “genes” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
-
Total-internal-reflection-based optical rotation quasi-phase-matching for efficient second-harmonic generation in Cadmium Germanium Arsenide crystal
Abstract: This study investigates a total-internal-reflection (TIR)-based optical rotation quasi-phase-matching (ORQPM) approach for second harmonic generation within a cadmium germanium arsenide crystal slab. The crystal is coated with a thin film of yttrium oxide to facilitate precise control over phase shifts between p- and s-polarized light upon reflection at the slab-film interface. By leveraging the interplay between TIR- induced optical rotation and fractional QPM effects at designated bounce points, the configuration …
Published in International Journal of Crystalline Materials · Vol. 3, Issue 1, 2026 Read article
-
Radio Frequency Next-Generation Advances
Abstract: Radio frequency (RF) technology is a key enabler for modern wireless communications, driving the evolution of telecommunications, healthcare, aerospace, defence and the Internet of Things (IoT). Faster, more reliable and energy-efficient communication systems have been developed at a rapid pace due to recent discoveries in RF engineering. This article discusses novel advancements in RF technologies including enhanced antenna design, millimeter-wave communication, software defined radio, smart spectrum management, and RF-based sensor …
Published in International Journal of Radio Frequency Innovations · Vol. 4, Issue 1, 2026 Read article
-
Contemporary Ethno-Religious Development Crises in Northern Nigeria with a Special Reference to Some States: Genesis, Implication, Impact and the Quest for Prospect
Abstract: A study has been conducted purely for the exploration of the remote and immediate factors that frequently lead to the outbreak of the studied subject matter in the region and period under review. In this study, a multitude number of published and unpublished sources have been put into use for appropriate historical reconstruction of some major obstacles associated with political, economic, social, tribal and religious aspects of the region and …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 32–40 Read article
-
Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
-
Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
-
FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
-
Overcoming Obstacles to an HIV-1 Cure: Advances in Genome Editing, Immune System Reprogramming, and Viral Reservoir Elimination
Abstract: Human immunodeficiency virus type-1 (HIV-1) continues to represent a major global health challenge despite the remarkable success of antiretroviral therapy (ART). Although ART effectively suppresses viral replication and prolongs survival, it cannot eradicate the virus due to the persistence of long-lived latent reservoirs. In recent years, innovative therapeutic strategies have been explored with the aim of achieving either a functional remission or complete viral elimination. Advances in genome-editing technologies, particularly …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
-
Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
-
Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
-
Cartridge-Based Nucleic Acid Amplification for Rapid Tuberculosis Diagnosis
Abstract: In terms of public health, tuberculosis continues to have a significant impact on people's lives. The process of determining the underlying cause of a sickness or condition in a patient is known as clinical diagnosis. It entails the use of numerous diagnostic methods, including physical examinations, laboratory testing, and imaging procedures for medical purposes. Smear microscopy, which are frequently utilized, have poor sensitivity and lengthy turnaround times, respectively. An innovative, …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 43–48 Read article
-
Quantitative Research on Gen Z Slang Terms for a Diverse Group of People
Abstract: This study objective is to determine the various individuals who employed vocabulary connected with Generation Z and to discover who those persons were. Through the use of Google forms, twenty Gen Z slang terms associated were posed to the various participants for testing. The data are collected from the participants by the researcher through the use of Google Forms, and the researcher is the one who is responsible for developing …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 24–31 Read article
-
Thalassemia and its management – A review article
Abstract: Thalassemia is a hemoglobinopathy burdening India making it earn title of Thalassemia capital of world. Studying last decade, the overall prevalence worldwide and incidence rates have declined but prevalence rates were high in east and Southeast Asian countries. Screening for carriers and affected individuals and genetic counselling are promising approaches for reducing soaring cases and reducing the further spread. Thalassemia affects various organs due to iron overload and haemolysis leading …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 60–73 Read article
-
Genomic Medicine Revolutionizes Heart Care: A New Standard of Practice
Abstract: The integration of genomic and precision medicine into cardiovascular healthcare represents a transformative advancement in addressing the global burden of cardiovascular diseases (CVDs). Precision medicine leverages genomic, proteomic, and metabolomic data to provide personalized care, optimizing treatment outcomes while minimizing adverse effects. Over the past decade, extensive research has highlighted its potential to revolutionize the management of major CVDs, including myocardial infarction, hypertension, and heart failure, which significantly contribute to …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 30–37 Read article
-
Forecasting Climate-Driven Healthcare Demand in Agricultural Regions: A Multi-Modal AI Approach
Abstract: The rapidly increasing instability of world climatic regimes has made past meteorological thresholds irrelevant, especially in the agricultural areas where monetary stability and well-being of humans are closely intertwined with an environmental situation. The more the frequency of 1 in every 1000-year events, i.e., heatwaves and catastrophic flooding increase, the greater the rural healthcare systems are in crisis, i.e., unable to predict a surge in demand because of data scarcity, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 28–38 Read article
-
Advance Fixed Point Theorems and Its Application to Ordinary and Fractional Differential Equations
Abstract: In the present research, advanced results on the fixed point theorem are applied to typical boundary value problems. Finding a differential equation's solution under certain boundary conditions is the goal of typical boundary value topics. The article appears to extend new fixed point results to a new context, likely involving fractional operators with unique kernels, notably the Caputo-type fractional operator. This extension involves applying the fixed point theorem to a …
Published in Recent Trends in Mathematics · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
-
Debris Flows in Mining Areas: Risk Assessment and Mitigation Strategies for Mine Waste Management
Abstract: This study investigates the dynamics and risks associated with debris flows, focusing on the differentiation between natural and mine-generated debris, particularly in storm-affected areas. Mine debris flows, frequently exacerbated by heavy rainfall and human activities, are a major concern due to their destructive potential and environmental impact. The research highlights key factors contributing to debris flow hazards, such as sediment composition, flow velocity, and terrain susceptibility. Additionally, the study explores …
Published in International Journal of Minerals · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
-
Antibiotic Resistance in Microbes: History, Mechanisms, Therapeutic Approaches, and Strategies for Mitigation
Abstract: The global emergence of clinically significant antibiotic resistance is increasingly linked to the environment. Antimicrobials, metals, and biocides are just a few of the substances that are released into the environment through paths that are regulated by environmental regulators. Consequently, environmental regulators ought to be heavily involved in developing national and international antimicrobial resistance (AMR) measures. Antimicrobial compounds from pharmaceutical waste, agricultural runoff, and wastewater discharge contribute to the spread …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–11 Read article
-
Needle Choice in Spinal Anaesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former's cuff to create an airtight seal. Of all the specialised masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are its four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
-
Needle Choice in Spinal Anesthesia: Is the 25-Gauge Whitacre Superior to the Quincke in Reducing Post-Dural Puncture Headache
Abstract: The process known as endotracheal intubation involves inserting a synthetic tube into the trachea and inflating the former’s cuff to create an airtight seal. Of all the specialized masks in the LMA family, the PLMA is the most intricate. The cuff, the airway tube, the drain (gastric access) tube, and the inflation line with pilot balloon are their four primary components. This drain tube aids in identifying mask malposition and …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 22–30 Read article
-
Cell Membranes as Therapeutic Targets: Implications in Infectious and Metabolic Disorders
Abstract: This is a review of the crucial role played by cell membranes in health and disease with respect to their contribution to infectious and metabolic diseases. Dysfunction of membranes, such as membrane transporter changes and changes in lipid content, has been associated with a variety of diseases, including diabetes, cardiovascular disease, and cancer. The present therapeutic approaches are focused on attacking membrane constituents by disrupting the entry of pathogens or …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 47–53 Read article