Search
93 articles for “Molecular weight”
-
Production, Optimization and Purification of Laccase Produced by Pleurotus ostreatus MH591763
Abstract: The optimization of production medium for laccase produced by Pleurotus ostreatus (Gene Bank Accession number MH591763) to reduce the cost of laccase production in large scale is the basic research in industrial field. In this study, the laccase culture medium was optimized for growth parameters such as incubation period, pH, temperature, carbon and nitrogen source on fungal growth and enzyme production. Purification and characterization of the enzyme was done by …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 56–64 Read article
-
Molecular Docking Technique Assisted Discovery of Some Hydroxylated Chalcone Molecules as α-glucosidase Inhibitors
Abstract: The present study involved exploration of the inhibitory potential of some A-ring hydroxylated chalcone compounds against PDB ID: 2QMJ file (Maltase-glucoamylase in complex with acarbose) with the assistance of iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present study highlighted the immense potentials of several unexplored hydroxyl group (in ring-A) containing chalcones in successfully inhibiting the one of the most effective anti-hyperglycemic based enzymatic target α-glucosidase. The research has …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 1, 2019 · pp. 34–38 Read article
-
In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
-
A Computational Approach to Study Reversible Aging in SHRP AAA-1 Asphalt
Abstract: This study is carried out computationally at atomic scale to determine reversible modifications of a specific group of asphalt. The specific asphalt group is defined by Strategic Highway Research Program (SHRP) as AAA-1. The chemical structure of AAA-1 asphalt is modeled using representative molecules drawn by LAMMPS software. LAMMPS molecular dynamics code is employed here to perform atomistic simulations. Simulation outputs give acceptable values of physical, thermodynamic and structural changes …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 5, Issue 3, 2014 · pp. 20–27 Read article
-
Synthesis and Characterization of Aminophenyl (p-hydroxyphenyl)Tellurium(IV) Dichlorides
Abstract: The synthesis and characterization of a number of aminophenyl(p-hydroxyphenyl)tellurium(IV) dichlorides with the general formula RR´TeCl₂—where R stands for the p-hydroxyphenyl group and R´ denotes substituted amino aromatic moieties like aniline, N-methylaniline, and N,N-dimethylaniline—are reported in this study. Because of their distinctive structural characteristics, adaptable bonding behavior, and prospective uses in organic synthesis, catalysis, and medicinal chemistry, organotellurium compounds have garnered a lot of interest. The coordination behavior and electrical characteristics …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 2, 2026 · pp. 01–06 Read article
-
Conductive Polymers for Electro-Mechanical Systems: Structure–Property Relationships and Mechanical Behavior Under Stress
Abstract: Conductive polymers represent a unique class of functional materials that combine the electrical characteristics of metals with the mechanical flexibility of polymers. These dual properties are critical for the next generation of electro-mechanical systems, including wearable sensors, soft robotics, structural health monitoring (SHM), and biomedical actuators. However, the mechanical performance of conductive polymers under diverse stress conditions—such as elongation, cyclic loading, bending, and impact—remains a key challenge, limiting their long-term …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 25–30 Read article
-
Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
-
Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
-
Analyzing The Mechanisms of Polymerization and The Related Kinetic Pathways Using Refined Analytical Methods.
Abstract: In numerous sectors, polymeric materials play a crucial role, yet effectiveness is largely determined by their molecular structure and the processing parameters utilized. This investigation presents an integrative approach aimed at delineating the connections between polymer structure, properties, and processing through sophisticated characterization methods. With the implementation of small angle X Ray Scattering (SAXS),NMR(Nuclear magnetic resonance( spectroscopy) FM(Atomic Force Microscopy) and rheological analysis, we analyze the complex interplay between molecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 86–94 Read article
-
QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
-
Polymer-Based Chemistry of Carbohydrate-Derived Fulvic Acid and Its Comparative Effect with Chelating Agents on Root Dentin Microhardness
Abstract: The interaction between the polymer science and the endodontic biomaterials field has increased recently while considering the search for chelating agents. CHD-FA (Carbohydrate-Derived Fulvic Acid), a naturally occurring low-molecular-weight polymeric organic acid, has potential chelating and antimicrobial and antioxidant activities. This investigation examines the polymeric chemistry of CHD-FA and compares the effect of CHD-FA with other chelating agents, ethylenediaminetetraacetic acid (EDTA), and citric acid, on root dentin microhardness. A total …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1051–1061 Read article
-
Polymer Chemistry and Nanocomposite Network Design of PEGDA-Based Hydrogels
Abstract: The chemical structure and crosslinking density of polyethylene glycol diacrylate (PEGDA) can be systematically tailored, making it a versatile polymeric network in biomedical engineering, drug delivery, tissue engineering, biosensing and advanced manufacturing. PEGDA is a polymerizable acrylate-functionalized hydrophilic PEG that can be polymerized to make three-dimensional networks via free-radical polymerization, specifically photoinitiated. The resulting network architecture depends on the PEGDA molecular weight, the concentration of precursors, the polymerization conditions, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
-
Synthesis ,Spectral Investigation, Anticancer Study of Azo-Imine Heterocyclic Compounds
Abstract: Many Schiff base reactions are known within a famous series of addition reactions to the azomethine group, where reagents are added to the polarized double bond and the nucleophilic (nucleophilic) reagents attack the carbon atom in the azomethine bond.. An example of this type of reaction is the addition of alkyl halides, which produces quaternary amine salts, which in turn are converted to the secondary amine. These compounds have an …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article
-
Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article
-
Recent Advances & Prospects of Transferosomes for Transdermal Delivery: Trends in Drug Delivery
Abstract: There have been several non-invasive administrations that have emerged recently to replace conventional needle injections. With its minimal rejection rate, remarkable ease of administration, and remarkable patient comfort and perseverance, the transdermal drug delivery system (TDDS) is the most attractive of them all. The skincare industry, which includes cosmetics, may also find use for TDDS in addition to the pharmaceutical industry. As this strategy mainly entails local drug administration, it …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 01–21 Read article
-
A Comprehensive Review on Pharmacological Properties of Coumarins
Abstract: Coumarins are a diverse group of secondary metabolites found in a variety of plant species (over 1200 different coumarins have been identified from natural sources, especially plants), as well as in fungi and microorganisms. Coumarin is a simple, widely occurring chemical structure in nature, present in many plants, fungi, and bacteria. In recent years, these natural compounds have attracted growing interest from the scientific community due to their broad spectrum …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 12–17 Read article
-
POTENTIAL BIOPRESERVATIVE EFFECT OF ANTIMICROBIAL PEPTIDES OF SEEDS OF Vigna unguiculata (Cow Pea) ON Hibiscus sabdariffa L. (Roselle) Calyces (Zobo) DRINK
Abstract: Natural and efficient food preservatives are in greater demand because of growing concerns about the safety and quality of processed beverages. Antimicrobial peptides have emerged as promising natural substitutes for synthetic preservatives, boasting advantages like wide-ranging activity and reduced toxicity. In this research, we investigate the inhibitory effects of these peptides against common spoilage microorganisms in 'Zobo' drink. Peptides were extracted and purified from germinated Vigna unguiculata) seeds harvested on …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 26–41 Read article
-
Responses of Phytoplankton Community Structure to Polycyclic Aromatic Hydrocarbon Constituents in Imo River, Oyigbo, Niger Delta, Nigeria
Abstract: Phytoplankton perform a pivotal role in the food chain and serve as indicator species in environmental studies. Polycyclic aromatic hydrocarbons (PAHs) are toxic group of divergent chemicals with two or more aromatic rings coalesce side by side representing serious persistent organic contaminants posing environmental risk to aquatic life and human. Imo River receive contaminants from illegal oil refinery. The study was conducted to assess the responses of phytoplankton community structure …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 1, 2025 · pp. 45–53 Read article
-
A Futuristics Pyrolysis Technique: Conversion of Waste Plastic Polybags Into Fuel
Abstract: Plastics are high molecular weight materials composed of repeating polymer units and can be classified based on factors like chemical composition, structure, stiffness, application types, and processing methods. A key environmental issue with plastics is their non-biodegradability, causing them to persist in the environment. Pre-consumer plastic waste includes manufacturing defects, rejected items, and excess materials produced during virgin plastic manufacturing. In India, around 15,342 tons of plastic waste are collected …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
-
Controlled Release of Anti-Inflammatory Drugs from Biopolymer Matrices
Abstract: Carefully releasing anti-inflammatory drugs from natural materials is a new way to make treatments work better and cut down on the side effects of current drug delivery methods. To slowly release drugs, this method uses safe, reusable materials. It's a good alternative to pills or shots. Anti-inflammatory drugs that are used to treat long-term conditions like gout and inflammatory bowel disease work better when they are made in a controlled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 388–399 Read article