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55 articles for “CAR T-cell therapy”
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Phosphorescence of Carbon Nanodots – The Phenomena and the Applications
Abstract: Photoluminescence has emerged as a fundamental phenomenon in modern biomedical science, enabling advanced diagnostic, therapeutic, and theranostic applications through light–matter interactions at the nanoscale. The ability of photoluminescent materials to absorb electromagnetic radiation and emit light at distinct wavelengths has been widely exploited in bioimaging, biosensing, drug delivery tracking, and photodynamic therapy. Among various photoluminescent nanomaterials, carbon nanodots have attracted significant attention due to their strong emission intensity, tunable fluorescence, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 01–05 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Cell Membranes as Therapeutic Targets: Implications in Infectious and Metabolic Disorders
Abstract: This is a review of the crucial role played by cell membranes in health and disease with respect to their contribution to infectious and metabolic diseases. Dysfunction of membranes, such as membrane transporter changes and changes in lipid content, has been associated with a variety of diseases, including diabetes, cardiovascular disease, and cancer. The present therapeutic approaches are focused on attacking membrane constituents by disrupting the entry of pathogens or …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 47–53 Read article
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Progeria Syndrome Unveiled: A Scientific Odyssey into Premature Aging Mechanisms and Therapeutic Frontiers
Abstract: Progeria, or Hutchinson-Gilford Progeria Syndrome (HGPS), is a rare and fatal genetic disorder in childhood, exhibiting features akin to premature aging. Despite normal appearances in infancy, affected children face accelerated aging with distinct facial characteristics, including micrognathia, dental malformations, lower body weight, early hair loss, decreased joint mobility, lipodystrophy, etc. The cause of HGPS is a point mutation that occurs at the exon 11 of the LMNA gene which normally …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 52–68 Read article
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Uncontrolled Cell Growth and Human Health: A Comprehensive Exploration of Cancer
Abstract: Cancer is a diverse category of diseases defined by the uncontrolled proliferation and spread of aberrant cells. It remains the major cause of morbidity and mortality worldwide. This article presents an overview of the various forms of cancer, such as carcinomas, sarcomas, lymphomas, and leukaemia, emphasising their distinct causes, symptoms, and risks. Early detection and diagnosis are emphasized as key to enhancing treatment outcomes. The article further provides an in-depth …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 1–23 Read article
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The Current State of Huntington's Disease Treatment: An Overview of Palliative Care and Symptom Management
Abstract: Huntington's disease (HD) is a neurodegenerative ailment that adversely affects the basal ganglia and the cortex of the brain. Although there is no recognized cure for HD, symptomatic relief and therapeutic management of the condition have improved over the course of time. This review paper provides an up-to-date overview of the current treatment options and symptom management strategies utilized in the care of HD patients. Additionally, it highlights the existing …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 Read article
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Management of Thermal Burns over Breast – Our Experience
Abstract: The intricate challenge of restoring normal anatomy with minimal deformity in burns over the breast region has prompted the development of innovative tissue regeneration approaches. Addressing the complex nature of challenging wound patterns necessitates a multidisciplinary team with diverse expertise. In our concerted effort, we have successfully integrated advanced reconstructive techniques with regenerative medicine modalities to enhance outcomes in the intricate realm of complex breast reconstruction post-thermal burns. Our approach …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Nurse’s Responsibility and Liability in Chemotherapy Formulation: Legal and Ethical Considerations
Abstract: Each year, over 16 million new cancer cases are diagnosed globally. Cancer causes cells to grow uncontrollably, potentially leading to the formation of tumors, immune system damage, and other debilitating effects that can be fatal. Common cancer treatments include surgery to remove tumors, chemotherapy, radiation therapy, hormonal therapy, and immunotherapy. Among these, chemotherapy plays a significant role, accounting for nearly half of the overall treatment approach. Chemotherapy drugs can be …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 15–20 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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Edible Mushrooms: Management of Diabetes Mellitus and Phytochemical Screening of Agaricus Bisporus
Abstract: A metabolic disease characterized by elevated blood glucose levels; diabetes mellitus affects millions of people. If not treated on time, it causes problems, damage organs, and even life-threatening. Studies have shown that diabetes can be avoided and controlled with a healthy lifestyle that incorporates exercise and a balanced diet. While there are several synthetic medications available to treat this illness using them over an extended period of time is linked …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
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Reinventing Drug Delivery Through Cutting-Edge Nanotechnology
Abstract: Nanotechnology has emerged as a revolutionary platform in the field of drug delivery, offering novel strategies for the precise, efficient, and controlled delivery of therapeutic agents. The integration of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanoparticles, has significantly enhanced drug solubility, stability, bioavailability, and targeted delivery to specific tissues or cells. Targeted drug delivery systems based on nanotechnology minimize off-target effects, reduce systemic toxicity, and improve …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 44–61 Read article
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A Review on Nano-emulsion for Delivery of Anti-cancer Drugs
Abstract: Cancer disease is characterized by abnormal cell growth. Malignant growth treatments have progressed significantly, yet there is a requirement for development in particularity and feeling of dread toward foundational harmfulness. Nanotechnology is the reconciliation of nanoscience into medication by the utilization of nanoparticles. The appearance of nanoscience in disease conclusion and treatment will assist clinicians with better surveying and oversee patients and further develop the medical care framework and administrations …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 7–13 Read article
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Role of Modified Egg Membrane in Donor Site Wound Healing
Abstract: An ulcer is essentially a small gap or tear in the skin that struggles to heal properly, persisting either suddenly or over an extended period. These persistent ulcers can present significant challenges for individuals, prolonging their discomfort and recovery. Medical professionals employ various techniques to aid in healing, including using skin grafts from different body parts, specialized coverings, or temporary solutions to protect the wound.In our research, we explored an …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 2, 2024 · pp. 16–20 Read article
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article