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134 articles for “Analgesics”
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Morphine: A Pharmacological Perspective on Its Cancer Pain Management
Abstract: Morphine continues to be a key treatment in managing cancer pain because of its strong pain-relieving effects and established clinical history. Despite the emergence of alternative opioids and pain management therapies, morphine continues to be widely prescribed, particularly in palliative care settings. However, its use has been accompanied by concerns regarding tolerance, dependence, and adverse effects, which complicate long-term administration. This review explores the pharmacological aspects of morphine in cancer …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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Impact Of Nurse-Led Pain Management Protocol On Postoperative Recovery Outcome
Abstract: Postoperative pain remains a critical determinant of recovery outcomes, influencing patient satisfaction, complication rates, and overall healthcare utilization. Nurse-led pain management protocols have emerged as an evidence-based strategy to enhance postoperative care through continuous assessment, individualized interventions, and multidisciplinary collaboration. This article explores the impact of nurse-led pain management on postoperative recovery outcomes, including pain reduction, early mobilization, decreased hospital stay, and improved patient satisfaction. Evidence from recent studies demonstrates …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 Read article
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Chironji (Buchanania lanzan): Chemistry, Health Benefits and Food Application: A Review
Abstract: The chironji (Buchanania lanzan Spreng.) belonging to the family of Anacardiaceae. It is an important non-wood tree species. It is investigated for their nutritional, phytochemical and antioxidant properties to understand its nutraceutical potential. It is an active source of phenolics, natural antioxidants and minerals. All parts of the plant, roots, rhizome, leaves, fruits, seeds and gum are used for the treatment of various disorders, such as wound healing, antidiarrheal, antiulcer, …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 10, Issue 2, 2021 · pp. 12–22 Read article
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Application of Prodrug to Improve Skin Permeability: A Review
Abstract: Administration of drug via skin has some limitations such as skin barrier, solubility of drug and partition coefficient etc. Stratum corneum which is an outer skin layer, acts as a barrier to the skin. Thus, prodrug has some applications to improve skin permeability. Prodrugs are defined as the compounds which are initially inactive but covert into their active form when reacted with several chemicals or enzymes at particular active site …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 1, 2023 · pp. 1–11 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Chompound contaning oxadiazole derivatives and their potential therapeutic uses.
Abstract: Derivatives of oxadiazole or furadi azole rings constitute a significant class of heterocyclic substances. Oxadiazole is a heterocyclic, five-membered ring with two carbons, one oxygen atom, two nitrogen atoms, and two double bonds. They are produced by substituting two nitrogen (-N =) atoms for two methylene groups (= CH) in furan. The furan ring's aromaticity was significantly decreased by substituting these groups, resulting in a conjugated diene character. There were …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 68–74 Read article
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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Impact of Pre-Operative Nebulized Lidocaine–Dexmedetomidine Combination Versus Monotherapy on Incidence, Severity, and Patient Comfort Scores of Post-Operative Sore Throat: A Randomized Controlled Clinical Trial
Abstract: Post-operative sore throat (POST) is a common issue after endotracheal intubation and can reduce patient comfort and hinder recovery. This randomized, double-blind clinical study investigated how effective pre-operative nebulized lidocaine, dexmedetomidine, and their combination are in minimizing POST. Eligible adult patients classified as ASA I–II and scheduled for elective surgery under general anesthesia were randomly assigned to three groups. Nebulization was administered 15–20 minutes before induction using standardized dosing and …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 29–35 Read article
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Acetaminophen: Current Understanding and Future Directions in Pharmacology
Abstract: In this review, acetaminophen is described as one of the most widely used analgesic and antipyretic medications worldwide due to its effectiveness and reduced gastrointestinal toxicity compared with traditional NSAIDs. Its precise mode of action is still unclear despite widespread therapeutic use. Acetaminophen has little peripheral anti-inflammatory effect and largely acts within the central nervous system, in contrast to NSAIDs, which mainly block peripheral cyclooxygenase (COX) enzymes and lower inflammation. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Pharmacological Management of Behavior in Children
Abstract: This research work aims to review various drugs used for the management of behavior in children. Pharmacological management describes the use of various drugs to manage the behavior of pediatric patients undergoing dental procedures. Several types of drugs and routes of administration (e.g. oral, recta, intramuscular, intravenous etc.) have been tested to achieve this aim. The use of sedative drugs along with local anesthetics has shown to reduce anxiety and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 11, Issue 1, 2020 · pp. 8–17 Read article
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Examining Thiocolchicoside from a Surgical Perspective
Abstract: Thiocolchicoside functions as a muscle relaxant, anti-inflammatory, and analgesic agent, effectively preventing and alleviating muscle spasm. It is widely recognized analgesic that effectively alleviates muscle pain and low back pain. This medication typically begins with the administration of paracetamol. For the alleviation of symptoms associated with low back pain, it is common practice to utilize a combination of non-steroidal anti-inflammatory drugs (NSAIDs), analgesic, and muscle relaxants. Low back pain (LBP), …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 3, 2023 · pp. 14–20 Read article
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Evaluation for Diuretic Activity of Cassia auriculata
Abstract: The present study has been designed to elucidate the pharmacological activities like analgesic, anti-inflammatory and diuretic activities of flowers of Cassia auriculata on albino mice and rats. The doses for pharmacological activities was fixed petroleum ether, methanol and aqueous extracts was 500 mg/kg b.w. respectively. Analgesic activity was carried out by Eddy’s hot plate method. In this model, nociceptive reaction toward thermal stimuli in mice is a well validated model …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 6–9 Read article
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Incised Surgical Wound Closure with Sutures and Staples: A Prospective Randomised Trial
Abstract: Increasing knowledge and present time demand in the field of surgery has enabled the development of new techniques of surgical wound closure that are not associated with contamination. The aim is to evaluate the advantages and disadvantages of skin closure with sutures and staples. A prospective randomized trial was carried out on a total of 100 patients divided into two groups of 50 each. Patients were in the age group …
Published in Research and Reviews : Journal of Surgery · Vol. 4, Issue 2, 2015 · pp. 10–14 Read article
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Ethanolic Root Extract of Jatropha curcas L. Relieves Muscle Pain in Rats
Abstract: The roots of Jatropha curcas are used traditionally to treat pain. The present study evaluated the analgesic property of ethanolic extract of Jatropha curcas (JAT) in acute and chronic muscle pain models. Acute muscle hyperalgesia was induced by injecting 3% carrageenan into the gastrocnemius muscles of rats. Twelve hours after the injection, baseline muscle hyperalgesia was measured and the rats were then treated orally with 30, 100 and 300 mg/kg/day …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 2, 2014 · pp. 5–10 Read article
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Management of Crop Foreign Body in a Juvenile Chicken (Gallus gallus domesticus)
Abstract: A one-month-old domestic chick (Gallus gallus domesticus) presented to the hospital with symptom of anorexia for the past one day was diagnosed to have a crop foreign body and decided for surgical correction. Under local analgesia, the crop was opened and the foreign body was removed. The ingluviotomy wound was closed by Cushing’s suture with size 3-0 Polyglactin 910 and skin wound by simple interrupted sutures using size 2-0 braided …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 8, Issue 3, 2019 · pp. 6–8 Read article
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A Review: Carissa Carendas Leaves: Phytochemical Constituents, Traditional Use, and Pharmacological Properties
Abstract: Carissa carendas called Karanda are used in many traditional systems Unani, Ayurveda, homeopathic systems. Traditionally various herbal drugs used in curing many diseases are used singly or in a combination of another herbal drugs. Carissa carendas is all part of plant-like fruit, root, leaves all parts is used to treat many diseases traditionally. Various herbal drugs individually or in combination have been recommended for the treatment of different diseases. The …
Published in Research & Reviews : Journal of Botany Read article
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A Review on Manihot Esculenta Species
Abstract: Manihot esculenta, which is commonly known as Cassava, is a woody shrub that provides a high source of carbohydrate. It is an annual crop native to tropical and subtropical regions of the world. Nigeria is the largest producer of the cassava plant. The parts of the plant like leaves, roots, stems, etc are consumed in a variety of ways as they have been shown to possess activities like analgesic, anti-inflammatory …
Published in Research & Reviews : Journal of Botany Read article
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An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article
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Drona-Chariot: A Medical Equipment Carrier Drone
Abstract: Caring for trauma victims in harsh environments poses numerous difficulties, especially when a rescue effort is delayed. Human-containable medical equipment may also be consumed by a single victim, making replenishment impossible prior to evacuation, especially in long-term on-site supply scenarios. This project aims to build an unmanned autonomous aerial vehicle that successfully delivers remote places with life-sustaining medical supplies where it is impossible or impractical for vehicles or pedestrians to …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 7–14 Read article