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490 articles for “investments”
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Navigating the Challenges of COVID-19: A Guide for Mental and Behavioural Health
Abstract: The COVID-19 epidemic has posed unique encounters globally, impacting various aspects of daily life, including mental and behavioral health. The present study attempts to prepare a guide with ways and means to navigate the challenges of the COVID-19 pandemic. This guide provides comprehensive insights and strategies for individuals to navigate these challenges effectively. The study began by addressing the psychosomatic effect of the pandemic, such as increased anxiety, depression, PTSD, …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 1–15 Read article
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Sleep Deprivation and Cognitive Performance: The Effects Of Varying Levels Of Sleep Deprivation On Cognitive Tasks
Abstract: The present study investigates the relationship between sleep deprivation and cognitive performance across various cognitive domains, with a focus on gender differences. A total of 139 participants were assessed using the Pittsburgh Sleep Quality Index (PSQI) and the Cognitive Failures Questionnaire (CFQ). The results revealed a moderate positive correlation between poor sleep quality and cognitive failures (r = 0.50, p < .001), indicating that individuals with greater sleep disturbances experienced …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Mind-Machine Synergy: The Evolution and Future of Brain-Computer Interfaces
Abstract: Brain-Computer Interfaces (BCIs) represent a transformative technology that enables the direct communication between the human brain and external devices, bypassing the traditional output mechanisms, such as speech or physical movement. BCIs hold the potential to revolutionize fields, such as healthcare, neuroscience, and human-computer interaction by providing new ways to restore lost functions, enhance cognitive abilities, enable seamless communication, and create novel user experiences across various platforms and environments. This article …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 19–31 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Post-Antibiotic Gut Microbiota Recovery in the Rumen: Insights into Colonization Patterns, Population Density, and Diversity Dynamics
Abstract: The post-antibiotic recovery of gut microbiota represents a critical area of research in understanding how microbial communities rebalance and re-establish homeostasis following antibiotic-induced disruptions. Antibiotics, while effective against infections, can cause substantial shifts in gut microbiota, leading to dysbiosis – a state of microbial imbalance that impairs gut health and functions. This recovery process involves multiple complex dynamics, including colonization patterns, population density, and the restoration of microbial diversity. The …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–17 Read article
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Excessive screen time: Understanding its long-term impact on health and behavior
Abstract: In today’s world, digital gadgets, like laptops, game consoles, smartphones, and televisions, are essential since they provide entertainment and convenience. However, their overuse has raised serious concerns regarding long-term health and social implications. This review investigates the extensive effects of excessive screen time on mental, physical, and social well-being, with a special emphasis on children and adolescents. The growing amount of time toddlers and preschoolers spend in front of screens …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 13–21 Read article
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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Multicriteria Decision Making using SR-Fuzzy Sets
Abstract: In this study, we introduce and explore square-root fuzzy sets (SR-Fuzzy sets), a novel extension within the realm of fuzzy set theory. We begin by establishing a comparative analysis between SR-Fuzzy sets and two well-known fuzzy set models: Intuitionistic Fuzzy Sets (IFS) and Pythagorean Fuzzy Sets (PFS). This comparison highlights the unique characteristics and mathematical structure of SR-Fuzzy sets. A particular focus is placed on the complement operator, which plays …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 12–20 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Assessment of Noise Pollution Level in Port Harcourt City: a Location Based Comparative Study
Abstract: Noise pollution has emerged as a significant environmental health concern in urban centers, particularly in rapidly developing cities like Port Harcourt, Nigeria. This study presents a comprehensive, location-based comparative assessment of ambient noise levels across selected zones within Port Harcourt metropolis, including residential, commercial, industrial, and traffic-dense areas. Sound level measurements were conducted in the different areas of Port-Harcourt metropolis. High-density and low-density residential neighborhoods, busy roadways, business centers, road …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 7–17 Read article
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Automated Crop Disease Detection Using Convolutional Neural Networks
Abstract: Crop diseases contribute to major losses in agricultural production worldwide generating enormous economic costs. This study investigates the possibility of Convolutional Neural Networks (CNN) imaging techniques to auto-detect diseases associated with plants through image processing. A model was developed and trained on a publicly available plant disease dataset containing labeled images of several diseases. The CNN could classify various plant diseases with accuracy of 95%, precision of 92%, and recall …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 7–15 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Advancements in Insect Science: Agricultural, Health, and Biotechnological Applications for Sustainability
Abstract: Insect research is very important for solving problems in agriculture, health, industry, and protecting the environment. This article talks about the many uses of entomology and how new study on insects helps with pest control, pollination, disease vector control, and the creation of bioinspired technologies. There is a lot of talk about integrated pest management (IPM) tactics, using insects in forensic investigations, and the new sector of producing insect- based …
Published in International Journal of Insects · Vol. 2, Issue 2, 2025 · pp. 7–14 Read article
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Epipelic Algae Assemblage and Nutrient Status as Indicators of Pollution in Alice Creek, Rivers State, Nigeria
Abstract: Background and Objective: Alice creek is a tributary of the Sombreiro River, Akuku-Toru Local Government Area, Rivers State, Nigeria, receiving various anthropogenic wastes. The study investigated the species composition, diversity, abundance, and distribution of epipelic algae, and the nutrient status of Alice creek, a tributary of Sombreiro river, Rivers State, Nigeria. Materials and Methods: Epipelic and nutrients samples were collected monthly between February and May 2020 from three (3) stations …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 · pp. 12–20 Read article
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AI and Access to Justice: An Indian Perspective
Abstract: Artificial intelligence is set to transform the legal profession, influencing everything from legal research and document review to legal advice and decision-making. This study investigates the possible uses of AI in the legal area, such as predictive analytics and AI-powered legal research tools. This study explains the role of AI in Judicial Systems. The study covers the related literature, challenges and opportunities in Indian judicial system. The usage of AI …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 2, 2025 · pp. 30–37 Read article
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Assessing Air Quality, Climate Change, and Migration Dynamics in Delhi NCR: A System Dynamics Approach
Abstract: As climate change accelerates and environmental degradation worsens, urban centers like Delhi NCR are under increasing pressure from internal migration. Poor air quality—especially in rural and peri-urban regions—emerges both as a driver of out-migration and a deterrent for in-migration to already burdened cities. This study develops a system dynamics (SD) model that integrates climate variables, air pollution metrics, economic indicators, governance quality, and migration behavior to simulate population flows into …
Published in Recent Trends in Mathematics · Vol. 2, Issue 1, 2025 · pp. 7–11 Read article
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Impact of Anxiety and Affect on Quality of Life among Youth
Abstract: Youth well-being is an important phenomenon comprising physical, psychological, and social health, where the psychological factors such as anxiety and affect play an essential role in determining Quality of Life (QOL). Young people experience multiple transitions and they are at risk of anxiety disorders that in turn can have adverse effects on academic achievement, physical health, emotional well-being and relationships. Furthermore, affect has a role in the management of emotions …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 1–13 Read article
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Influence of Personality Traits on Motivation and Engagement among Adolescents During Online Education
Abstract: This study investigates how the Big Five personality traits—openness, conscientiousness, extraversion, agreeableness, and neuroticism—affect motivation and engagement among adolescents in online education settings. During the COVID-19 pandemic, online learning became a necessity, but not all students adapted equally. A sample of 600 students aged 16 to 19 years from 30 inter colleges in the Gwalior district participated in this research. Data were collected using a structured questionnaire measuring personality traits …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 Read article