Search
618 articles for “Drug–protein interactions (DPIs)”
Nothing matched all of your words, so these match any of them.
-
Clinical Profile of Dengue Patients who had a Prior Infection with the Covid 19 Virus in a Tertiary Care Centre
Abstract: This cross-sectional analytical study conducted in a tertiary care center aims to investigate the clinical profile of Dengue virus-infected patients with a prior history of COVID-19 within the last three years. Dengue, a prevalent tropical disease, ranges from mild fever to severe conditions like hemorrhagic fever and shock syndrome. The study utilizes the World Health Organization's 2009 classification for Dengue and delineates the febrile, critical, and recovery phases of infection. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 34–38 Read article
-
Parcel Delivery & Journey Companion Finder
Abstract: The idea of the project is to provide an interactive platform for people to help each other to carry their parcels from one place to another. The platform even provides a feature for finding a travel companion for the journey and thus helps in reducing their expenses. The parcel delivery and journey companion finder is a web-based system designed primarily for the users, so that they can find parcel services …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 2, 2023 · pp. 31–40 Read article
-
A Study of ROI Based Sign Language to Text Translation in Real Time Using Deep Learning
Abstract: Since sign language is their primary form of communication, it plays a significant role in the lives of hearing and speech disabled people. However, since not everyone is conversant in sign language, it is challenging for the disabled to interact with others daily. Sign language is made up of a variety of hand gestures that may stand in for a wide range of words and sentiments. The purpose of this …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 8–14 Read article
-
Crack Propagation Analysis in Metallic Alloys: A Comparative Study of Traditional and Advanced Materials
Abstract: A vital component of materials science and engineering, crack propagation analysis is essential to determining the structural integrity and dependability of materials. Designing safe and long-lasting structures for a variety of sectors required an understanding of how cracks begin, spread, and interact with a material's microstructure. To guarantee the performance, safety, and dependability of materials in a variety of applications, crack propagation analysis is essential. It offers insightful information about …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 33–41 Read article
-
An Adaptive Approach for Real-Time Embedded System Design, Analysis and Optimization
Abstract: Real-time embedded systems are critical components in various domains, such as automotive, aerospace, healthcare, and industrial automation. The design, analysis, and optimization of these systems are vital to ensure their reliable and efficient operation. In this paper, we propose an adaptive approach for real-time embedded systems that aims to address the challenges faced during the development process while maintaining high-quality results. Our approach leverages adaptive techniques to dynamically adjust the …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 8–14 Read article
-
Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
-
Hand Gesture Recognition Systems: A Review of Vision-based and Sensor-based Approaches
Abstract: With many real-world uses, such as sign language translation and human-computer interaction, hand gesture detection is a crucial area of study in the science of computer vision. In this study, we propose a Convolutional Neural Network (CNN) model that uses real-time camera images to recognise hand gestures. A collection of hand motion photographs spanning the English alphabet (A-Z) was gathered, and the images were pre-processed to exclude any backdrop and …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
-
Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
-
Life Cycle Assessment (LCA): A Tool for Sustainable Development and Environmental Management of Products
Abstract: Life cycle assessment (LCA) is a crucial technique for clearly understanding how much room there is for product improvement in a given good or service. Because of its high cost and application in eco-design, supply chain management, green buying, sustainable investing, and other relevant activities, manual data engineering and analysis processes. Traditional LCA methodologies and technology may need more scalability regarding substantial product portfolios and expanding reporting requirements. The Sustainability …
Published in International Journal of Industrial and Product Design Engineering · Vol. 1, Issue 2, 2023 · pp. 16–25 Read article
-
Implementation and Impact of RFID in Library Management Systems
Abstract: This system relies on UHF RFID scanners at the gate and transaction section, which are supported by antennas and RFID transceivers embedded in library cards. These devices allow information to be electronically stored and read/written using radio waves without the need for physical interaction. It does not require manual input and instantly sends information about books and library users to the library's management system. It has a record-keeping and search …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 20–25 Read article
-
Personalized Nutrition and Exercise: Pioneering the Path to Precision Medicine
Abstract: Preventive healthcare is about to undergo a major shift thanks to the personalised exercise and nutrition paradigm, which is based on precision medicine concepts. In order to create tailored recommendations for improving health outcomes and preventing chronic diseases, this article explores the integration of genetic profiling, metabolic evaluation, and lifestyle factors. A person's response to food and exercise depends heavily on genetic and metabolic variances, which emphasises the need of …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 42–46 Read article
-
Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
-
The Emergence of Coxsackievirus A16 Associated with HFMD Colloquially Termed ‘Tomato Flu’ in India 2022: A Detailed Virological Inspection
Abstract: As the world battles the COVID-19 pandemic and grapples with a concerning spike in monkeypox cases, India has encountered another viral illness dubbed "Tomato Flu." Tomato Flu is a viral disease caused by coxsackievirus A16, which is a highly infectious illness affecting children under 10 years old.. Enterovirus A71, CV-A16, CVA6, and echoviruses are the causes of what is also referred to as hand, foot, and mouth disease (HFMD). The …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 29–40 Read article
-
The Impact of Dietary Components on Lactation: A Critical Review
Abstract: Infant growth and well-being depend on an adequate and species-specific amount of nutrients, antibodies, and immunological components, which are provided by human breastfeeding, the cornerstone of newborn sustenance and development However, some moms struggle with producing inadequate milk, which can put the health advantages of nursing for both mother and child in jeopardy and cause stress, anxiety, and perhaps early weaning. This review discusses the fascinating idea that food changes …
Published in International Journal of Nutritions · Vol. 1, Issue 1, 2024 · pp. 31–36 Read article
-
Alopecia Areata: Complex Roots and Potential Cures
Abstract: Autoimmunity is when the healthy organs of an individual’s body are attacked by its own immune system, leading to illness or functional abnormalities. The hair follicles (HFs) are wrongly destroyed by the immune system in a condition known as Alopecia Areata and results in chronic non-cicatricial hair loss discernible by spherical patches. It’s a severely worsening or relapsing malady that can be permanent during severe falling out of hair. In …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 41–54 Read article
-
Stretching Boundaries: A Comprehensive Review of Ehlers-Danlos Syndrome and its Subtypes
Abstract: The Ehlers-Danlos syndromes (EDS) encompass 13 inheritable disorders affecting connective tissue. These conditions arise from genetic alterations impacting the structure of connective tissue. Every variant of Ehlers-Danlos syndrome (EDS) exhibits distinct features and has specific diagnostic criteria. While certain traits such as joint hypermobility, skin hyperextensibility, and tissue fragility are common across all types of EDS. The range of clinical presentations spans from minor skin and joint looseness to severe …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 44–57 Read article
-
Unveiling the Synergy: Sciatica, Arthritis, and Their Integrated Approach to Wellness
Abstract: This comprehensive review delves into the intricate connection between sciatica and arthritis, unraveling the etymological roots of “sciatica” from its ancient Greek and Latin origins. Tracing the historical aspects of sciatica back to the teachings of Hippocrates, the fifth-century BC Hellenic physician, sets the stage for a contemporary exploration of the interplay between these conditions. The sciatic nerve, including nerve roots spanning from L4 to S3, stands out as the …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 22–31 Read article
-
Social Capital as a Predicting Indicator to Measure the Psychological Health Impacts of COVID-19 Pandemic on Urban Societies in Pakistan.
Abstract: The COVID-19 pandemic has forced people to adapt to massive changes in their lifestyles; from health to work and how they interact with everyone nearby they know. This study aims to investigate the psychological wellbeing-impacts of COVID-19 on social capital in Pakistan. Social capital means the social and cultural coherence (as a predicting indicator) in the society. This was a survey based study conducted in 5 major cities (Islamabad, Rawalpindi, …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 12–21 Read article
-
Importance of inflammatory marker ratio and lipid profile ratio in Acute Ischemic Stroke
Abstract: Background: Acute Ischemic Stroke is a chronic inflammatory disease that is projected to be one of the leading causes of mortality affecting millions of people globally. It is essential to study the Platelet lymphocyte ratio (PLR), Neutrophil lymphocyte ratio (NLR) ratios and C reactive protein (CRP) in impacting the inflammatory status during stroke. It is also important that altered lipid metabolism could influence the inflammatory conditions associated with AIS. Hence …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 19–31 Read article
-
Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article