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1968 articles for “1” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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PHD-2 Activation to Stabilize HIF-1α and FASN in Mammary Gland Cancer
Abstract: Activation of prolyl hydroxylase-2 (PHD2) has emerged as an attractive target to counteract tumor hypoxia and thereby uncontrolled cellular proliferation. We utilized an integrated strategy to identify new PHD2 activators using series of in silico tools and in vitro methods. The in silico screening helped to identify 4-ethyl-3-(4-methoxyphenyl)-2,2-dimethyl-2H-chromen-7-yl acetate (BBAP-3), [4-(7-acetyloxy-4-ethyl-2,2-dimethylchromen-3-yl)phenyl]acetate (BBAP-4), 3-(4-methoxyphenyl)-2,2,4-trimethyl-2H-chromen-7-yl acetate (BBAP-5) as an activator, who are structurally similar to KRH102140 (a known activator of PHD2). All …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 28–33 Read article
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The Doomsday Clock and Global Health: A Medical Sociological Analysis of Existential Threats to Human Civilization From 1947 to 85 Seconds to Midnight Situating the Biosocial Crises of the Twenty-First Century
Abstract: Since its inception in 1947, the Doomsday Clock maintained by the Bulletin of the Atomic Scientists has functioned as a socially constructed barometer of civilisational risk, translating complex scientific, geopolitical, and technological threats into a universally legible symbolic chronometry. As of January 2026, the Clock stands at 85 seconds to midnight, its most alarming position in nearly eight decades of operation. This article adopts a medical sociological framework, drawing on …
Published in Recent Trends in Social Studies · Vol. 3, Issue 2, 2026 · pp. 26–36 Read article
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Review on Design and Development of Cleaning and Cooling System for 15 kw (Thermal) Down Draft Gasifier with Producer Gas Analysis
Abstract: In this global world, energy crisis is increasing day-by-day, but fulfilling of that energy by conventional energy generation produces pollution problem and it is also costly. The process of biomass gasification was carried out in a downdraft gasifier by using different biomass like neem wood, babul wood, coconut coir and sugarcane bagasse as feed materials. The product gas or syngas produced was studied by varying parameters like temperature of operation, …
Published in Journal of Thermal Engineering and Applications · Vol. 3, Issue 2, 2016 · pp. 31–37 Read article
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Corporate Governance Philosophy and Non-Mandatory Disclosures: A Study of Top 10 Companies in India
Abstract: The Agency Problem has given a rise to and a need for the present system of Corporate Governance. Corporate Governance implies the conduct in which a company is managed to the paramount interest of all the concerned stakeholders. Though it is a legal compulsion to adhere to the Corporate Governance Practices, some of the companies try to exceed the legal standards. The present paper is an attempt to study the …
Published in Journal of Production Research & Management · Vol. 0, Issue 0, 2011 · pp. 24–33 Read article
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Ultrasonic Studies in Binary Liquid Mixtures of Butylamine and Iso-Butylamine with 1-Decanol at 293, 303 and 313 K
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Acoustic parameters like isentropic compressibility, acoustic impedance and intermolecular free length along with internal pressure of butylamine and iso-butylamine with 1-decanol have been determined from sound speed, density and viscosity measurements at 293, 303 and 313 K over the entire range of composition. These derived parameters were used to calculate excess functions like deviation in isentropic compressibility, excess acoustic impedance, excess intermolecular …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 4, Issue 1, 2013 · pp. 43–53 Read article
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Study of the Hammett equation for oxidation of 2 – Hydroxy – 1 - Naphthalidene Anil and para substituted chloroanils by potassium bromate in acid medium
Abstract: The kinetics of oxidation of the Schiff base and its substituted anils by potassium bromate in aquo-acetic acid medium has been studied in this work. The study of thermodynamic parameters is done, and the rate constants for the reaction are determined. The plot of log{ks/k0} against the substituent constant (ï³ ) is plotted for para and meta substitution and the reaction constant (ï²) is calculated. The plot of ï„H against …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 7, Issue 2, 2016 · pp. 1–4 Read article
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Phenetic Analysis of Solanum melongena Accessions to Explore the Genetic Diversity by SDS-PAGE
Abstract: The present experimental work was conducted for the phenetic analysis among 40 accessions of Solanum melongena from different geographical areas of Pakistan. The interspecific variation was found among the accessions of S. melongena. The analysis of seed storage was done by SDS-PAGE to check their relationship. Electrophoretic data was documented by gel documentation system (Bio-Rad, USA), and analyzed by using quantity 1-D analysis software and dendogram constructed with 100% tolerance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 2, Issue 2, 2012 · pp. 21–34 Read article
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Study of Aerobic and Anaerobic Bacteriological Profile in Patients Presenting with Ear Discharge and Antimicrobial Susceptibility Pattern of Aerobic Isolates
Abstract: Ear discharge is a major health problem in both, developed and developing countries. This study was undertaken to determine the pattern of the different etiological aerobic and anaerobic bacteria in patients presenting with ear discharge and clinically diagnosed as CSOM and ASOM and also to know the antibiogram of aerobic bacteria in Kota Rajasthan. A prospective study was carried out in department of microbiology, MBS Hospital, Kota, among 100 patients …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 23–30 Read article
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Induction of Specific Cytotoxic Lymphocytes in Goats Vaccinated with Fractionated Antigens of Brucella melitensis 16M
Abstract: The present study investigated the ability of different fractionated antigens of Brucella melitensis 16M to induce cytotoxic T-lymphocytes. For this study, soluble Lipopolysaccharide and outer membrane protein antigens were fractionated by using gel filtration chromatography and found 6, 5 and 5 fractions respectively of each antigen. All the regions of antigens were analyzed for their ability to induce cytotoxic T-lymphocytes. This study investigated that SAG5, LPG1 and OMPG4 induce maximum …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 2, 2013 · pp. 12–18 Read article
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Biochemical Biomarkers as a Tool in Chromium Induced Toxicity to Green Tiger Prawn, Penaeus semisulcatus (De-Haan, 1844)
Abstract: Estuarine ecosystem and its biodiversity are at higher risk due to coastal contamination by heavy metals and conservation of biodiversity can be accomplished by utilizing biomarkers of pollutant at different exposure levels. In the present study, chronic toxicity test was conducted to evaluate the antioxidants and enzymes as the possible biomarkers in Green Tiger Prawn, Penaeus semisulcatus. The chronic endpoint value (MATC), no-observed effect concentration (NOEC), and low-observed effective concentration …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 2, 2014 · pp. 1–12 Read article
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Study on the Failures of Raw Water Tower Structural Joints When the Air Gap of the Jack up Rigs is Increased
Abstract: 1. ABS Rules for Building and Classing Offshore Installations.2. Guidelines for Site Specific Assessment of Mobile Jack-up Units. SNAME T&R 5-5A.3. ABS. RP-2A, WSD, Recommended Practice for Planning, Designing and Constructing Fixed Offshore Platforms- Working Stress Design. 21st Edn. Dec 2000; Suppl 1–3.4. Ohta T, Yamauchi H, Toriumi M. Design Method of Leg Structure of Jack-up Rigs. NKK Corporation, Engineering Research Centre, Kawasaki, Japan. 1st International Offshore and Polar Engineering …
Published in Journal of Offshore Structure and Technology · Vol. 6, Issue 1, 2019 · pp. 39–48 Read article
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Evaluating Building Density Analysis Using Geographical Information System
Abstract: In Mekelle city, urban sprawl is continuously expanding to the surrounding hinterland at an alarming rate without considering the inner infill area of the city. Moreover, several numbers of developers and land speculator hold large tract of vacant land. This has resulted because land speculators buy large aggregation lands and develop small part of their plot and keep the land until the price rises up. And this creates low density …
Published in Journal of Remote Sensing & GIS · Vol. 10, Issue 1, 2019 · pp. 24–39 Read article
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Ginger Extract Inhibits the Replication of T2 Bacteriophage by Inhibiting the Synthesis of Nucleosides
Abstract: Extracts of ginger inhibit the growth of bacteria and viruses of animal cells. At concentrations of 1, 2, 4, and 6 ml of a ginger extract per 100 ml of LB broth, E. coli replication was 104.6, 117.7, 117.7, and 122.8% of the control. At concentrations of 2, 4, and 6 ml of ginger extract per 100 ml of LB broth, the yield of T2 bacteriophage decreased by 36.2, 41.8, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 7, Issue 3, 2017 · pp. 20–27 Read article
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Ocean Surface Features Extraction using Morphological Techniques from Sentinel-1A Data
Abstract: SAR (Synthetic Aperture Radar) imagery of the ocean surface obtained from remote sensinginstruments is one of the prominent research areas. In this paper, detection of oceanicfeatures from SAR using morphological technique is proposed. The detected surface featuresare presented in layered form. The main advantage of such representation is features can beeasily enabled or disabled on SAR image. Algorithm is tested on Sentinel-1A dataset of oceansurface.Keywords: SAR Images, Surface Features, Layered …
Published in Journal of Remote Sensing & GIS · Vol. 11, Issue 2, 2020 · pp. 1–4 Read article
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Evaluation and Morphological Diversity Study of Table Banana (Musa spp.) Genotypes at Jamalpur Region of Bangladesh
Abstract: Twenty-one table banana genotypes viz. Amrit Sagar, BARI Kola-1, Basrai, Binisuta, Champa, Dudsagar, Ganasundari, Grandnaine, ITC-1262, ITC-1310, ITC-1319, ITC-1320, ITC-1332, ITC-1441, ITC-570, Kabri, Kanaibashi, Lakatan, Madna, Sabri, and Sagar, were studied to evaluate the performance of yield and yield contributing characters and morphological diversity at the fruit farm and fruit characteristics were studied in the laboratory of the Horticulture Research Centre, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 9, Issue 2, 2019 · pp. 13–24 Read article
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In vitro Propagation of Geranium (Pelargonium Graveolens L.) from Nodal Culture
Abstract: AbstractThe present study was initiated to optimize in vitro propagation protocol from nodal culture of geranium. Three surface sterilization treatments were tested, and treatment three-surface sterilization (treatment of explants with 1.5%(w/v) fungicide (Kocide 101) mixed with one drop of soup solution for 1 min, 70% ethanol for 1 min and with 1% NaClO for 3 min and again with 70% ethanol for 1 min was used throughout the experiment with …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 4, Issue 2, 2015 · pp. 23–34 Read article
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Production and Evaluation of Particleboard using Sugarcane Bagasse in the case of Woniji-Shewa Sugar Factory
Abstract: Particleboard is a wood-based panel product manufactured under pressure and temperature from the particles of wood or other any lignocellulosic fibrous materials and a binder. Particleboard manufacturing is ecologically sound, as the waste material will transform into useful products, thereby conserving natural resources. The objectives of this study was production and evaluation of particleboard using sugarcane bagasse in the case of Woniji-Shewa Sugar Factory. The ratio of the surface and …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 10, Issue 2, 2019 · pp. 27–42 Read article
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Behavioural Changes among Fadama 11 Project Farmers and Lessons in Agriculture Development of Enugu State, Nigeria
Abstract: AbstractThe study analyzed the behavioral changes and Fadama II project farmers and lesson in agricultural development of Enugu State, Nigeria. A structural interview schedule was used in sourcing information from one hundred and sixty farmers using simple random sampling technique. The data obtained were analyzed using both, simple descriptive and inferential statistics, namely percentages and chi-square analysis. The result obtained showed that the project farmers were mostly male (95%) and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 5, Issue 2, 2016 · pp. 17–26 Read article
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Performance Evaluation of Barbari Goats in Semi-Arid Region of India: A Review
Abstract: Barbari goat, a medium sized dual purpose goat breed in India, is known for its good lactation performance, high prolificacy, early maturity, low kidding interval, high kidding rate and better growth rate. The average weights of kids at birth, 3, 6, 9 and 12 month of age were 1.66±0.47, 5.88±0.41, 9.36±0.17, 12.85±0.25 and 16.08±0.35 kg, respectively. The average pre-weaning (0–3 months) daily weight gain was 59.9 g while post weaning …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 2, 2016 · pp. 25–29 Read article
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Effect of Kitchen Waste Compost and Vermicompost in Combination with Chemical Fertilizer on the Production of Capsicum
Abstract: A study was carried out at the research field of the Horticulture Research Centre (HRC), Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during October 2013 to April 2014 to develop standard production method of capsicum under GAP. BARI Mistimorich-1 was used in the study. Eight treatments were constructed with the fully matured compost for each evaluation, these were, T1=Recommended dose of Chemical fertilizers (RD), T2= …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 2, 2019 · pp. 7–15 Read article