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387 articles for “Systematic”
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A Review on the Regulatory Study for Implementation of Schedule-M Amendments in Pharmaceutical Industries in India
Abstract: A major regulatory change in pharmaceutical manufacturing industry in India is the introduction of the updated Schedule M (2023–2024). The aims to compliance the country's Good Manufacturing Practices (GMP) with international quality standards. The review evaluates the Schedule M amendments implementation strategies, industrial impact and regulatory relevance. Legislative texts, official notices, WHO GMP reports, ICH guidelines, guidance documents of CDSCO and peer-reviewed literature were all explored as part of the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Enhanced Sustainable Concrete Mix Design Using LLMs and Advanced Machine Learning Techniques
Abstract: Large Language Models (LLMs) are emerging as transformative tools in materials science, offering human-like reasoning, zero-shot problem solving, and the ability to integrate fuzzy laboratory knowledge with structured data. This study extends and reinterprets the original systematic benchmark for using LLMs in sustainable concrete design, particularly for Alkali-Activated Concrete (AAC). We introduce an enhanced, multi-model framework combining LLM-based inverse design, Random Forest regression, Gaussian Process Regression (GPR), and a lightweight …
Published in Recent Trends in Civil Engineering & Technology · Vol. 16, Issue 2, 2026 Read article
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Ayurvedic Management of Vātadhika Vātarakta – A Case Series
Abstract: Vātarakta is a classical disorder described in Ayurveda that arises due to the simultaneous vitiation of Vāta and Rakta, resulting in a pathological condition characterized by mutual obstruction (Āvaraṇa) between these two factors. This complex interaction between Vāta and Rakta leads to a wide spectrum of clinical manifestations, making the condition challenging to diagnose and manage effectively. Among the four types of Vātarakta described in classical texts, Vātādhika Vātarakta predominantly …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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A Study to Assess the Risk Factors and Symptoms of Dialysis Disequilibrium Syndrome among Patients Undergoing Hemodialysis
Abstract: Dialysis Disequilibrium Syndrome (DDS) is a rare but potentially life-threatening neurological complication associated with hemodialysis, particularly during initiation or in high-risk patients. It is characterized by a spectrum of neurological manifestations ranging from mild symptoms such as headache and nausea to severe outcomes including seizures, coma, and death. Early identification of risk factors and prompt recognition of symptoms are crucial to prevent morbidity and mortality. The present study aimed to …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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A Clinical Insight Into Management of Left Sided Hydrocele through Homoeopathy: A Case Report
Abstract: Hydrocele is a common condition in pediatric age groups, characterized by the accumulation of serous fluid within the tunica vaginalis surrounding the testis. While many cases resolve spontaneously within the first one to two years of life, persistent hydrocele beyond this period is generally managed surgically. The present case highlights the role of individualized homoeopathic treatment as a conservative approach in such conditions. A 2-year-old male child presented with left-sided …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 1–11 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Polymer-Inspired Underwater Friction Stir Welding of Aluminum–Copper Composite Joints
Abstract: The problem of high-performance dissimilar joints and their compatibility with polymer and composite engineering applications is the impetus to the current work. This paper seeks to investigate the possibility of applying the polymer-based composite ideas with underwater friction stir welding (UWFSW) to improve the performance of AA5083 aluminumcopper joints. To achieve this a systematic experimental method was followed by varying the tool rotational speed, traverse speed and tilt angle and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 372–383 Read article
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Optimized Utilization of Kota Stone Slurry Waste in Fly Ash–Based Geopolymer Mortar: A Taguchi-Driven Approach
Abstract: The large-scale generation of stone-processing wastes presents a critical sustainability challenge and an opportunity for value-added reuse in construction materials. This study develops a high-performance fly ash geopolymer mortar by partially replacing Class F fly ash with Kota stone slurry waste (KSSW) and optimizing the key mix parameters using a Taguchi design framework. Five governing factors—binder replacement level, NaOH molarity, sodium silicate–to–sodium hydroxide ratio (SS/SH), curing temperature, and alkaline solution-to-binder …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 426–445 Read article
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Structure–Property Correlation of Infill Topology and Density on Tensile and Flexural Performance of FDM-Printed PLA and ABS
Abstract: Additive Manufacturing (AM), particularly Fused Deposition Modeling (FDM), has become a widely adopted manufacturing technology due to its design flexibility, low cost, and capability for rapid prototyping. However, the mechanical performance of FDM-printed components is strongly influenced by internal structural parameters such as infill pattern and infill density, in addition to the intrinsic material behaviour. This study investigates the structure–property relationship between infill topology, density, and mechanical performance of PLA …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 26–37 Read article
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Design and Performance Analysis of Natural Rubber–Silica Nanocomposite Vibration Isolators for Household Appliances
Abstract: Natural rubber (NR) nanocomposites reinforced with surface-modified precipitated silica (SiO2) were synthesized through a two-roll mill compounding and compression-moulding process, then systematically evaluated as passive vibration isolator materials for domestic washing machine applications. Five silica loadings 0, 5, 10, 15, and 20 phr were investigated. A comprehensive characterization suite encompassing tensile testing, Shore A hardness, dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), and scanning electron microscopy (SEM) revealed clear structure–property …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 554–560 Read article
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Natural Frequency Analysis of Polymer Composites
Abstract: Polymer composite materials are increasingly utilized in vibration-sensitive engineering applications due to their high strength-to-weight ratio, design flexibility, and tailorable dynamic properties. Among these properties, natural frequency plays a crucial role in determining structural stability, resonance avoidance, and dynamic performance. This review presents a comprehensive synthesis of recent research on the natural frequency characteristics of polymer composite structures, with emphasis on material properties, structural configurations, boundary conditions, damage effects, environmental …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 541–553 Read article
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Synergistic Effects of Hybridized Nano-Silica and Hemp Fiber Reinforcement on Bio-Epoxy Composites
Abstract: Natural fiber-reinforced bio-epoxy composites have become promising sustainable alternatives to conventional synthetic-fiber petroleum-based materials, but are often limited by low fiber-matrix interfacial bonding, low thermal stability, and high moisture absorption which limit their application in structural applications. These issues are discussed in this work, by carrying out a systematic investigation of the synergistic effects of the hybridization of nano-silica particles with alkali-treated hemp fibers in a bio-epoxy matrix the composites …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 214–228 Read article
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Polymer Encapsulants for Photovoltaic Modules: Electrical Insulation Performance and Long-Term Durability under Accelerated UV Exposure
Abstract: Influence on the reliability and service life of PV modules is a major issue, which is influenced by the encapsulant degradation in long-term exposure to the sun's ultraviolet (UV) radiation. A systematic accelerated UV aging study of Ethylene Vinyl Acetate (EVA), Polyolefin Elastomer (POE), and Polyvinyl Butyral (PVB) films under IEC 61215-2:2021 specified test chamber conditions of Q-UV is conducted. The material properties were tested at various exposure intervals including …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 384–408 Read article
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Mechanical Characterization and Machinability Optimization of Stir-Cast Al6061–SiC Metal Matrix Composites
Abstract: This study presents the fabrication, mechanical characterization, metallurgical analysis, and machinability optimization of Aluminum 6061 reinforced with Silicon Carbide (SiC) metal matrix composites (MMCs) at three weight fractions: 5%, 7.5%, and 10%. Composites were manufactured using the stir casting technique, followed by comprehensive mechanical testing (tensile, hardness, and impact), optical microscopy, and scanning electron microscopy (SEM). Machinability was assessed through turning experiments on a lathe using an L9 Taguchi orthogonal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Structural Performance Evaluation of Circular Perforated Plates under Mechanical Loading
Abstract: Circular perforated plates are structurally critical components in aerospace, automotive, and marine sectors, where perforation-induced stress concentrations govern failure under mechanical loading. This study conducts a systematic finite element analysis of stress distribution, deformation, and interlaminar behavior in aluminum and glass-epoxy laminates ([−45/45/90/0]S and [−45/45/90/0]AS) under uniform transverse pressure with clamped-free boundary conditions. Four perforation configurations—no hole, central hole, single-series, and 25-hole grid—were evaluated using ANSYS Shell-181, verified against Kirchhoff–Love, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 1–20 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Formulation and Evaluation of a Polyherbal Lip Scrub Containing Beetroot, Licorice, and Aloe Vera
Abstract: The current research is aimed at developing and assessing a polyherbal lip scrub which contains beetroot extract, licorice extract and aloe vera gel to enhance better exfoliation, nutritional and depigmentation. The fusion method was applied to the herbal extract formulations by varying systematically the concentration of the herbal extracts to develop the 4 formulations (F1-F4) each of 15 g. These prepared formulations were tested on their important physicochemical and functional …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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High-Performance Polymer Composite Membranes for Selective Ion Transport in Advanced Energy Conversion Systems
Abstract: The development of high-performance Polymer Composite Membranes (PCM) with enhanced ion transport is essential for Polymer Electrolyte Membrane Fuel Cells (PEMFC). However, low-humidity conditions and filter agglomeration still limit long-term membrane stability. This research designs a functionalized PCM integrating cross-linked Poly (Vinyl Alcohol)/Poly (Ethylene Glycol) (PVA/PEG) matrix with sulfonic acid functional groups and Titanium Dioxide (TiO₂) nanofillers to improve selective ion transport under low-humidity conditions. Two types of PCM were …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 724–736 Read article
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Machine Learning-Based Quantification of Polymer Structure Property Relationships for Predictive Material Design
Abstract: Polymer structures exhibit complex, hierarchical arrangements that strongly influence macroscopic properties, yet consistent quantification remains challenging due to nonlinear interactions and limited unified modeling strategies. Existing approaches inadequately capture generalized structure–property mappings across diverse polymer systems. This research aims to establish a machine learning-based quantification model for polymer structure–property relationships to support predictive material design. A Polymer Structure Property Dataset of 5,000 polymer samples includes structural descriptors and experimentally measured …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 737–754 Read article
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Polymer Nanocomposites and Functional Materials for Lithium-Ion Battery Supercapacitor Hybrid Energy Storage Systems: Materials, Interfaces, and Performance Perspectives
Abstract: The growing need for high-performance energy storage solutions in electric vehicles, renewable energy applications, portable electronics, and other sectors has accelerated research and development efforts in Lithium-Ion Battery–Supercapacitor Hybrid Energy Storage Systems (HESS). By combining the high energy density of lithium-ion batteries with the high power density and fast charge/discharge characteristics of supercapacitors, HESS offers a promising approach to meeting diverse energy storage requirements. Nevertheless, several critical challenges remain that …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 96–113 Read article