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747 articles for “Targets”
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Chompound contaning oxadiazole derivatives and their potential therapeutic uses.
Abstract: Derivatives of oxadiazole or furadi azole rings constitute a significant class of heterocyclic substances. Oxadiazole is a heterocyclic, five-membered ring with two carbons, one oxygen atom, two nitrogen atoms, and two double bonds. They are produced by substituting two nitrogen (-N =) atoms for two methylene groups (= CH) in furan. The furan ring's aromaticity was significantly decreased by substituting these groups, resulting in a conjugated diene character. There were …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 68–74 Read article
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The Role of Color in Influencing Consumers
Abstract: Marketers have long used color's ability to attract customers' attention. Products with attractive packaging will definitely attract the attention of customers and differentiate themselves from other products on the shelf. Many studies have shown that color dulling can occur when the representation of color relationships is not consistent. Thus, the purpose of this study is to comprehend how color influences consumers. In order to find out the participants' preferred colors, …
Published in International Journal of Behavioral Sciences · Vol. 1, Issue 1, 2024 · pp. 39–49 Read article
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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A study to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients admitted in intensive care units of a selected tertiary care hospital Ludhiana, Punjab
Abstract: Weaning is a gradual transition from full invasive ventilatory support to spontaneous ventilation with minimal support. This conducted to assess the effect of nature-based sound therapy among Mechanically Ventilated Patients admitted in Intensive Care units. An experimental design (randomized controlled trial) was used to assess the effect of nature-based sound therapy during weaning among Mechanically Ventilated patients.30 patients were drawn from the target population by using convenience sampling technique and …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 44–48 Read article
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Landmine Detection Robot with Live Surveillance
Abstract: Abstract Nowadays in war-torn communities around the world, landmines are causing immense civilian casualties. A land mine is an explosive device, which is meant to destroy or disable enemy and buried under or on the ground, especially in the mined countries like Afghanistan and Iraq. Accordingly, the majority of land mines are located under the ground surface and are triggered by pressure or tripwire. Mostly the surface of the landmines …
Published in Journal of Remote Sensing & GIS · Vol. 15, Issue 1, 2024 · pp. 28–35 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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Railway Track Safety System
Abstract: Railway Track Safety System (RTSS) is a comprehensive monitoring system specifically designed for the Indian railways. It consists of three subsystems that target specific challenges faced by the railways. Our main focus is on addressing four key problems. The first two issues involve cracks in the rails and foreign objects on the tracks. Cracks can occur naturally or be intentionally created to derail trains. Objects like stones can accidentally roll …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 1, 2024 · pp. 29–33 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Chemical Preparation Methods of Nano Material with their Applications
Abstract: Scientists were not satisfied with the diagnosis, exploration, injection and imaging through modern medical nanotechnology, but they were also able through this technology to activate smart microscopic bombs that target the cancer cell and detonate it, killing the cancer cells. This technology was tested on laboratory mice and achieved great success. Nanotechnology is the technology of the future, not only in the medical and therapeutic aspect, but also in everything …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 1–9 Read article
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Unveiling Nature’s Potential: In Silico Exploration and Identification of Herbal Remedies for Major Depressive Disorder Through Molecular Interaction Studies
Abstract: Major depressive disorder (MDD), a globally discussed mental health condition, has drawn significant attention because of its unique and intricate nature. This is marked by the enduring presence of negative emotions stemming from a lack of interest, diminished self-esteem, and excessive rumination. Despite the widespread availability of various antidepressant medications, their effectiveness is hindered by low response rates, prolonged treatment durations, and the prevalence of side effects, such as headaches, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 54–62 Read article
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Agrobot: IoT Enabled Crop-care
Abstract: Agriculture serves as the foundation of global civilization, particularly in nations like India, where it accounts for roughly 70% of the GDP, underscoring its pivotal role in economic stability. Despite its significance, traditional agricultural practices have often overlooked critical elements such as disease identification and precise pesticide application, focusing primarily on conventional methods like harvesting and seedling techniques. To address these gaps and usher in a new era of efficiency …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 1, 2024 · pp. 38–45 Read article
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A Critique of Advanced Instrumentation for Supervising and Regulating Renewable Energy Systems
Abstract: The integration of renewable strength property into the power grid necessitates modern-day tracking and manipulate systems to ensure highest best average overall performance, reliability, and performance. This paper offers a comprehensive analysis of advanced instrumentation applied for monitoring and controlling renewable strength systems. Beginning with an outline of renewable energy assets and their importance in addressing environmental worries and electricity sustainability, the compare delves into the challenges inherent in monitoring …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 1–12 Read article
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Remote Controlled Boat for Hyacinth Removal
Abstract: This research focuses on the design and production of Hyacinth infestation poses a significant ecological and economic challenge in many aquatic ecosystems, causing disruptions in water quality, biodiversity, and water transportation. To address this issue, we have developed a remote-controlled boat specifically designed for hyacinth removal. This innovative solution leverages the capabilities of autonomous watercraft, equipped with advanced sensors and a specially designed cutting mechanism, to efficiently and effectively manage …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 1, 2024 · pp. 20–26 Read article
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Smart City Based Manhole Monitoring System
Abstract: Urban environments are increasingly reliant on complex underground infrastructure networks, with manholes serving as critical access points for maintenance, inspection, and drainage. However, traditional manhole monitoring methods, often manual and labour-intensive, can be inefficient and prone to human error. This can lead to serious safety and health hazards, such as accidents caused by open manholes, exposure to harmful gas leaks, and infrastructure damage from overflows due to undetected blockage This …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 1, 2024 · pp. 27–34 Read article
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The Effect of Working Capital Management with Net Operating Profit of Manufacturing Companies
Abstract: This study attempts to show the impact of working capital management on operating profit for manufacturing organizations in order to reach profit targets and increase sales. Additionally, it seeks to determine whether working capital management significantly affects a company's operating net profit. Working capital management factors such as average collection period, daily balance turnover, average payment period, cash conversion cycle, and net exchange turnover of the business are considered in …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 1, 2024 · pp. 29–36 Read article
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InSilico Analysis and Homology Modeling of Tetrahydroprotoberberine Oxide involved in the Berberine Biosynthesis
Abstract: Objective: Berberine, a bioactive compound found in various plant species, exhibits diverse pharmacological properties with potential applications in pharmaceutical research. The biosynthesis of berberine involves several enzymatic steps, with (S)-tetrahydroprotoberberine oxidase playing a pivotal role. This study aimed to elucidate the structural and functional characteristics of (S)-tetrahydroprotoberberine oxidase to better understand its role in berberine biosynthesis and its potential biotechnological applications. Methods: Using bioinformatics tools and computational methods, the physicochemical …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 7–26 Read article
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The Impact of Internet Accessibility and Infrastructure on Rural Online Shopping Behavior
Abstract: This study examines the crucial connection between rural consumers‘ online buying habits and internet availability and infrastructure in those places. The study finds that increased access to the internet has a beneficial impact on rural areas’ adoption of e-commerce. In these areas, trust and security concerns were found to be important determinants of online shopping behavior, in addition to demographic differences. The findings highlight the significance of overcoming internet-related difficulties …
Published in E-Commerce for Future & Trends · Vol. 11, Issue 2, 2024 · pp. 22–28 Read article
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Floristic Diversity and Phenological Aspects of Paddy Field Weeds of Janjgir-Champa, Chhattisgarh
Abstract: Present study deals with survey of floristic diversity and phenological aspects of paddy fields weeds of Janjgir-champa. A survey was done during 2019 to 2023, at the peak point of weed growth. An unwanted plant which is harmful to farmers and crop is called weed. For this study, study area was divided into five sites viz. (Aphrid, Champa, Kurda, Hathnevra and Naila). In present findings 112 weed species belonging to33 …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 2, 2024 · pp. 13–30 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article