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1882 articles for “CRISPER cas-9” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Effect of Massage with Roghan Biskhapra (Oil of Trianthena Portulacastrum L.) in Rheumatoid Arthritis: Case Reports of Two Patients
Abstract: Rheumatoid arthritis is a common disorder related with pain and deformity with a prevalence of 0.5–1% in general population; and with an estimate 5–50 per 100000 new cases recorded annually. The present line of treatment in conventional medicine depends on the use of disease-modifying antirheumatic drug (DMARD) such as methotrexate, nonsteroidal anti-inflammatory drugs (NSAIDs), glucocorticoids or surgery. But the above said treatment methods are known to be associated with one …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 3, 2015 · pp. 1–3 Read article
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Shitapitta (Urticaria)—A Case Series Showing Efficacy of Virechana Therapy
Abstract: Ayurveda can safely be applied to heal many difficult conditions [1]. Shitapitta (Urticaria) is a type I hypersensitivity reaction which is manifested because of exposure to such allergens. Epidemiology of Urticaria is increasing nowadays due to industrialization and agriculture. Skin diseases are a major health problem among all the age group and are associated with significant morbidity. Two cases were studied in the present paper—males 16 years & 19 years …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 2, 2017 · pp. 7–11 Read article
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Evaluation for Diuretic Activity of Cassia auriculata
Abstract: The present study has been designed to elucidate the pharmacological activities like analgesic, anti-inflammatory and diuretic activities of flowers of Cassia auriculata on albino mice and rats. The doses for pharmacological activities was fixed petroleum ether, methanol and aqueous extracts was 500 mg/kg b.w. respectively. Analgesic activity was carried out by Eddy’s hot plate method. In this model, nociceptive reaction toward thermal stimuli in mice is a well validated model …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 2, 2018 · pp. 6–9 Read article
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A Case Study of Laryngeal Narrowing with Glossopharyngeal Neuritis in Insulin Dependent Diabetes Patient
Abstract: Neuritis is a very common complication met in with chronic diabetics. Commonly, peripheral nerves are involved but involvement of cranial nerves is not a common phenomenon. Involvement of cranial nerves or autonomic nerves may produce serious medical emergency that requires prompt management for life saving followed by long term control management. Such a case of insulin dependent diabetes mellitus with laryngeal narrowing and glossopharyngeal neuritis was met in a clinical …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 4, Issue 1, 2017 · pp. 9–14 Read article
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A Case Report on Ceftriaxone Induced Immediate Allergic Reaction
Abstract: The most common classes of drugs causing hypersensitivity reaction are antibiotics especially β-lactam antibiotic: cephalosporin’s and penicillin’s. Ceftriaxone, a third generation cephalosporin is used for variety of infections. This drug is associated with rare as well as mild side-effects such as urticaria, skin rash, diarrhea, vomiting, transient neutropenia, and hemolytic anaemia etc. We hereby try to present an adversary case report of a 19 years old male patient in which …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 33–35 Read article
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Efficacy of Panchakarma in a Patient of Multiple Myeloma: A Case Study
Abstract: The role of Ayurveda is now globally recognized for the quality of life. It has both, the preventive and curative potentials. Panchakarma is one unique principle of Ayurveda which deals with detoxification of body and mind. In this article, a case study of patient suffering from multiple myeloma will be discussed and how his quality of life changed after getting Panchakarma therapy. A male patient aged 67 years; known case …
Published in Trends in Drug Delivery · Vol. 4, Issue 2, 2017 · pp. 11–15 Read article
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Management of Katishoola with Shodhana and Vaitarana Basti: A Case Study
Abstract: Lower back pain is common in middle age. Management of this depends upon the condition, acute or chronic and the cause on which the orthopedic decides whether it is an emergency or conservative line of treatment is sufficient. In Ayurveda, trikagraha and katigraha come under Vatavyadhi. For Vatavyadhi, the common line of treatment mentioned in classics is Snehana, Swedana and Mridu Samshodhana. In this case, patient came with MRI report …
Published in Trends in Drug Delivery · Vol. 4, Issue 2, 2017 · pp. 16–19 Read article
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Cultural Heritage of Punjab: A Shift in Outlook and Output—A Case Study of the Historical Town of Sirhind
Abstract: Cultural heritage is an expression of ways of living developed by a community and passed on from generation to generation. This could be the tangible assets, such as buildings, monuments, archaeological sites, artifacts, landscape, and intangible assets such as oral traditions, folklore, language, and knowledge. Though all these can be viewed, analyzed, studied separately, they cannot be experienced as standalone entities. The understanding of our cultural heritage is fragmented and …
Published in International Journal of Architectural Design and Planning · Vol. 1, Issue 2, 2023 Read article
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Effective Homoeopathic Management of Allergic Rhinitis: A Case Series Utilizing Hepar Sulph 30 and Histamine 30 with Dietary Modifications
Abstract: Background: Allergic rhinitis (AR), means our immune system intruded by some allergens which is typically a harmless substance. These allergens are found in the air we breathe, in the food we eat, in the water and fluids we drink. These allergens are attacking on our immune system and the immune system responds to the allergens by releasing histamine and chemical mediators that cause symptoms in the nose, throat, eyes, ears, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 2, 2024 · pp. 12–16 Read article
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Breast Cancer: Susceptible Genes and Significant Risk Factors
Abstract: Breast cancer is the most common malignancy affecting women globally. In 2012, around 1.67 million new cases were reported worldwide. With the increase in life expectancy in developed countries, the incidence of breast cancer among older adults has risen significantly. In 2017, an estimated 252,710 new cases of invasive breast cancer were recorded, along with 6,341 cases of breast cancer in situ in the USA. About 24% of all breast …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 36–43 Read article
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Effective Ayurvedic Management of Dadru Kustha with Herbo- mineral Aushadhi yoga: A Single Case Study
Abstract: The skin, as the body's largest organ, is highly prone to various disorders due to its size and exposure to external factors. The majority of skin conditions are often the result of infections, including those caused by fungi or bacteria. In Ayurveda, skin diseases are grouped under the term 'Kustha' and are further categorized into MahaKustha and KshudraKustha. Among these, Dadru is a notable condition, classified as Raktapradoshaja Vikara, with …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 3, 2024 · pp. 26–31 Read article
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Harmonizing Philosophies: An In-Depth Exploration of Homeopathic Case Management through the Lenses of Dr. Boenninghausen, Dr. Kent, and Dr. Boger
Abstract: This article examines the distinct yet converging philosophies of three pivotal figures in homeopathy: Dr. Boenninghausen, Dr. James Tyler Kent, and Dr. Cyrus Maxwell Boger. Each of these practitioners has significantly influenced homeopathic practice through their unique approaches to case management, symptom evaluation, and remedy selection. By analyzing a case of membranous dysmenorrhea drawn from Dr. Kent's archives, we applied methodologies from each of these pioneers, revealing how their philosophical …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2024 · pp. 6–12 Read article
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Amlodipine induced peripheral edema and gingivitis – A case report.
Abstract: Calcium channel a group of drugs used to treat heart disorders are called blockers. These drugs dilate blood vessels and improve blood flow to heart, these works by preventing calcium flow through ion -specific (L- type) calcium channels in the cell membrane. Amlodipine, a calcium channel blocker in the dihydropyridine class, can cause peripheral edema and drug-induced gingivitis in some patients. In this case, the patient experienced swelling in the …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 45–49 Read article
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Enhancing Workplace Safety through Behaviour-Based Safety (BBS): A Case Study and Experimental Analysis
Abstract: Behavior-Based Safety (BBS) is a method designed to enhance workplace safety by concentrating on the actions and behaviors of workers. It works by encouraging a proactive safety culture where everyone is actively engaged in preventing accidents. This article explores the principles of BBS, describes an experimental case study conducted at a manufacturing facility, and presents the outcomes and implications. The case study used Behavioural observation, feedback, and training as interventions …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 2, Issue 2, 2024 · pp. 25–28 Read article
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Sustainable Materials in Architectural Design: Case Studies of Carbon- Neutral Buildings
Abstract: The architectural sector is under growing pressure to lower its carbon footprint, mainly by reconsidering material selections, as the need to slow down climate change becomes more pressing. With an emphasis on creative material uses in numerous international architectural projects, this review article examines the vital role that sustainable materials play in creating carbon-neutral buildings. The need for alternative, low-carbon materials that may accomplish comparable performance levels with a less …
Published in International Journal of Architectural Design and Planning · Vol. 2, Issue 2, 2024 · pp. 70–74 Read article
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Holistic Ayurvedic Approach to Managing Vicharchika (Eczema): Insights from a Case Study
Abstract: Background: Eczema is a common skin condition characterized by inflammatory reactions, manifesting as erythema, scaling, and itching. Nipple eczema is a localized dermatitis involving the nipple and areolar region, characterized by erythema and scaling. It may be itchy and painful and occasionally affect non-atopic breastfeeding women. Eczema has quite a resemblance with Vicharchika in Ayurveda. Vicharchika is characterized by skin manifestations having the symptoms Kandu (itching sensation), Pidika (papule), Shyava …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 · pp. 1–9 Read article
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Pharmacogenomics in Anesthesia: Case Studies and Clinical Applications for Personalized Care
Abstract: Pharmacogenomics, the study of how genetic variability influences individual responses to medications, is transforming anesthetic practice by enabling personalized care. This case study collection explores the integration of pharmacogenomic insights into anesthesia management, highlighting its impact on safety, efficacy, and patient outcomes. Adverse reactions to anesthetics often arise from genetic polymorphisms that alter drug metabolism or sensitivity. For instance, patients with RYR1 mutations are susceptible to malignant hyperthermia (MH) when …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 85–91 Read article
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Bal Ex Module with Prayer Regimes Improves Standing Dynamic Balance of balance disorders cases
Abstract: Integrating prayer regimes into balance rehabilitation, a well-established approach for patients with balance disorders offers an intriguing dimension to the therapy that had been incorporated in this Bal Ex Homebased video module for balance rehabilitation. Vestibular rehabilitation, often exemplified by Cawthorne-Cooksey exercises and their customized variants, effectively addresses symptoms like vertigo and instability. However, it's important to approach the inclusion of spiritual practices with sensitivity, acknowledging patients' diverse beliefs and …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 10–14 Read article
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Effect of 4-Week Protocol of Kegel Exercise on Pelvic Floor Strength on a Patient with Ovarian Endometriosis—A Case Report
Abstract: Purpose: The purpose of this case study was to describe the effects of Kegel exercise in a 4-week protocol for a patient with endometriosis associated with urinary incontinence. Case description: A 23-year-old female patient presented with chronic low back pain and also complained of difficulty in holding urine and leakage while doing forceful activities like lifting heavy objects, coughing, and sneezing in the past 6 months. She also complained of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 9–14 Read article
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Single Case Study on the Effectiveness of Macquarie Injury Management Group (MIMG) Protocol on the Subject of Primary Osteoarthritis of Knee
Abstract: Aim: To check the effectiveness of Macquarie Injury Management Group (MIMG) protocol in subject of primary osteoarthritis of knee. Purpose: Manual therapy has been shown to be an effective treatment for knee osteoarthritis, but it is necessary to evaluate the effectiveness of the MIMG manual therapy technique. However, there is a dearth of literature on the effectiveness of Macquarie injury management group (MIMG) protocol in subject of osteoarthritis of knee. …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 7–12 Read article