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1972 articles for “4-dioxopyrimidine-5-carbonitrile” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Arsenic Induced Cytotoxicity Study Against Human Epithelial Carcinoma (HeLa) Cell
Abstract: The present investigation was undertaken to find out the cytotoxic effects of various amounts of arsenic exposure to human epithelial carcinoma (HeLa) cell. Cells were treated with a final concentration (0, 10, 20, 30, 40 and 50 µg/l) of arsenite in 5 ml MEM for 24 h where 0 concentration was considered as control. Cell viability was determined by the trypan blue (TB) exclusion test using hematocytometer and automated BIO-RAD …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 1–8 Read article
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An Exploratory Pilot Study on the Traditional Siddha Anthropometric Diagnostic and Screening Method ‘Manikkadai Nool Measurement’ of Undergraduate Students in Thiruvananthapuram District of Kerala, India
Abstract: Aim: The aim is to study the distribution pattern of Manikkadai Nool measurement of students studying in an undergraduate college in Thiruvananthapuram district, Kerala and analyse the data statistically. Manikkadai Nool measurement is the circumference of forearm which is measured four-fingerbreadth above the wrist. Background: The traditional Tamil Siddha medical text ‘Agasthiyar Sudamanikkayaru Sutram’ exclusively discusses Manikkadai Nool measurement as a continuous variable ranging from 4 to 10 fb with …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 5–11 Read article
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Fabrication, Interfacial Characterization, and Superparamagnetic Properties of Fe₃O₄@γ-Fe₂O₃ Core/Shell Nanoparticle-Reinforced Chitosan Biopolymer Composites
Abstract: Magnetite/maghemite core/shell nanoparticles were prepared by alkaline co-precipitation of Fe(II) and Fe(III) precursors followed by controlled thermal oxidation at 350 °C and subsequently incorporated into chitosan at 1, 3, and 5 wt% loadings by solution casting. The resulting films were evaluated by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), high-resolution transmission electron microscopy (HR-TEM), vibrating-sample magnetometry (VSM), thermogravimetric analysis (TGA), and tensile testing. XRD showed the characteristic cubic spinel reflections …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Quality Appraisal for the Ornamental Bird, Fish, Dog, and Cat Foods Available in Bangladesh
Abstract: The study aimed to assess if the chemical composition of different avian, aquatic, dog, and cat foods commonly available in Chattogram, Bangladesh adheres to the recommended standards. Food samples were collected and subjected to proximate analysis for the dry matter (DM), crude protein (CP), crude fibre (CF), ether extract (EE), nitrogen free extract (NFE), and total ash (TA). The plant seeds used for ornamental birds exhibited substantial variability in terms …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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Performance Evaluation of Dominant Red Barred D922 Breed at Peri-urban Areas of Gurage Zone in SNNPR of Ethiopia
Abstract: Animal production in general and chickens in particular play important socioeconomic roles. The aim of this study was to evaluate the performance of red barred dual breeds in peri-urban areas of the Gurage zone and to determine the economic feasibility under farmers’ management conditions to promote and disseminate the approved technology packages to the users. Participant farmers were selected purposively on the basis of willingness to cover all associated package …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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The Study of Gravimetric Thermal Analysis and Some Physical Properties of a Binary Polymeric Mixture of Unsaturated Ester and Peach Seed Powder
Abstract: Strengthening polyester resin and increasing its hardening was studied by adding peach seed powder. We also studied how to change the thermal properties after strengthening the resin by adding different weight percentages of peach seed powder (5%, 10%, 15%). The thermal properties of polyesters were studied before and after cementing, which included thermogravimetric analysis (TGA) and treatment at different temperatures (21, 51, 81, 121, 151ºC.) The effect of acidic functions …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 33–46 Read article
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Knowledge About Reproductive Health Among Adolescent Girls in Selected Colleges: A Cross-sectional Study
Abstract: Introduction: Future generations' health is greatly influenced by the reproductive health of adolescent girls. For adolescent females to live healthy lives and safeguard against reproductive health issues, knowledge about reproductive health is crucial. The study's primary goal is to evaluate the pre-existing knowledge of reproductive health among adolescent girls studying in selected colleges. Methodology: A descriptive cross-sectional research with 200 teenage college-bound girls was done. The questionnaire was pre-designed and …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 27–31 Read article
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Perceptions and Attitude of Registered Nurses Towards Professionalism in Nursing from Selected Hospitals of Guntur District, Andhra Pradesh: A Comparative Study
Abstract: Background: Nursing professionalism refers to a collection of principles that are essential to raising the standard of patient care while enhancing the methodology, norms, and judgement that direct nursing activities on a daily basis. The main objective of the study is to assess the perceptions and attitude of registered nurses towards professionalism in nursing. Materials and Methods: A comparative descriptive research design adopted for this study. The study conducted at …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 1–7 Read article
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Assessment of Knowledge and Estimated Burden of Life Style Diseases in a Rural Community
Abstract: Although rapid human evolution has brought about advancement, it has also caused several lifestyle ailments. People’s daily routines have drastically changed as a result of emerging technologies, and it paved the way for numerous life style disorders. According to reports, lifestyle diseases are a major cause of increased mortality globally. Our study highlights the prevalence of life style diseases in the rural community and the need for early identification and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Form
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Tobacco Use Among Government and Public School Students in the Sangam Vihar Area of South Delhi
Abstract: The most fundamental right inherent to all human beings, as recognized in international law, is the right to health. Men and women worldwide prioritize good health as their top aspiration when asked to rank their desires. Currently, one of the most significant global challenges to achieving this desire is the widespread epidemic of tobacco use. This exceptional epidemic is notable not just for its magnitude but also for its characteristics. …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article
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Effects of Soil and Water Conservation Measures on Selected Physico-Chemical Properties of Soil in Qenshiben Watershed Central Ethiopia Regional State
Abstract: One of the main causes of declining soil resources in Ethiopia has been identified as soil erosion, which in turn negatively affects the agricultural productivity of the country. In order to alleviate the problem of soil erosion, numerous soil and water conservation measures have been implemented during the past ten years in numerous parts of the country through community mass mobilization. In spite of the fact that conservation measures had …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 1, 2024 · pp. 23–32 Read article
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Chemical Profile and Toxicity of Fresh and Dry leaves of the Essential Oils of Vetiveria zizanioides (L.) Nash. From Southwest Nigeria
Abstract: The fresh and dry leaves of Vetiveria zizanioides (L.) Nash (Gramineae) plant was collected, air dried and authenticated at the University of Ibadan Herbarium with voucher number: UIH-23237. The plant's dried, fresh leaves were hydro distilled in a Clevenger device to extract the essential oils. The oils were characterized by Gas Chromatography-Mass Spectrometry (GC – MS) while the toxicity of the essential oils was tested using brine shrimps’ lethality assay. …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 1, 2024 · pp. 44–49 Read article
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Lived Experience of Married Middle-aged Women Regarding Marital Satisfaction
Abstract: Introduction: Marital satisfaction is a significant contributor to general sense of happiness. A fulfilling marital relationship meets the intimacy requirements of both partners and contributes to their overall physical and mental well-being. However, elderly couples in today's era face new challenges associated with prolonged longevity. A study was conducted to explore the lived experience of marital satisfaction among married middle-aged women in selected community in Kannur. Objective of study was …
Published in International Journal of Women's Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 47–51 Read article
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Characterization of Synthesized Heterocyclic Oxadiazole Derivatives Using Mass, UV, IR, and NMR Spectroscopy, Among other Spectroscopic Techniques: Review
Abstract: The current study synthesized and assessed 3-heteroarylazo 4-hydroxy coumarin derivatives' initial antibacterial activities in vitro against four distinct pathogenic bacterial strains, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Ampicillin, a common medication, was used to compare each compound's antibacterial properties. UV, IR, 1H NMR, mass spectroscopy, and X-ray diffraction examinations were used to analyze the compounds. By using UV–vis spectra, the solute-chromic behavior of these compounds was …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article
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Initiation of Distress in Asphalt Concrete After Practicing Moisture Damage
Abstract: The moisture damage of asphalt concrete is considered as major type of distress in heavy rainfall environment. In this work, the decline in the initial flexural stiffness of asphalt concrete was monitored after practicing the moisture damage process. The variations were analyzed relative to the control mixture. Asphalt concrete mixtures were created in the laboratory with the optimal binder content. Extra mixtures were also prepared with ±0.5% variation of binder …
Published in Trends in Transport Engineering and Applications · Vol. 11, Issue 2, 2024 · pp. 7–13 Read article
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An Evaluation of the Impact of Deep Breathing Exercises on Reducing Academic Stress in B.Sc. Nursing Semester Students
Abstract: Introduction: Academic stress nowadays is one of the considerable problems in nursing students which need to be tackle for improvement of their profession. Objectives: The objectives of the study were a) To assess level of stress among 3rd semester and 4th semester BSc Nursing students (b) To assess the effectiveness of selective self-help technique among 3rd semester and 4th semester B.sc Nursing students, (c) To compare pre-test and post-test score …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 8–16 Read article