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954 articles for “stabilizer”
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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Analytical Investigation on Structural Optimization of Commercial Building Using Braced Frames and Masonry Diagonal Strut
Abstract: Enhancing the overall stability and structural performance of commercial buildings are important in particular regions which are prone to various seismic activity. This research emphases on enhancing the seismic performance of commercial buildings by integrating masonry diagonal struts with concentric braced frames. The main aim is to ensure structural safety of a building while also keeping the design economical and efficient. In this study high-rise buildings with 12, 16, and …
Published in Recent Trends in Civil Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 14–23 Read article
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Rising Temperatures and Surface Mass Loss in Greenland: Implications for Regional Glacier Dynamics and Global Sea Level Rise
Abstract: In Greenland, the ice sheet serves as one of the strongest indicators of global climate change, with consistently rising temperatures driving it toward an even more negative mass balance. Over the last two decades, warmer conditions have exacerbated surface melting, darkened ice, and resulted in feedback stimulating further loss. This study assesses how those temperature trends—particularly during summer peak months—have impacted the stability of Greenland's ice, and then, more importantly, …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 15–22 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Theoretical Study of Z = 122 Nuclei
Abstract: We used atomic nuclei with proton number Z = 122 to calculate bulk properties within the relativistic mean field (RMF) theory. We utilized the force parameters recognized as NL3 in our calculations. We extend our calculation to isotopic series of Z = 122 and analyses the theoretical outcomes. A whole isotopic chain of nuclei with atomic number 𝑍 = 122 Z=122 is included in our inquiry, enabling a methodical examination …
Published in Journal of Nuclear Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 1–9 Read article
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Synthesis, Identification and Bio Evaluation of New Thiophene Derivatives
Abstract: Thiophene is considered one of the most effective cyclic sulfur compounds in organic and pharmaceutical chemistry due to its high stability in various chemical reactions. It plays a key role as an antifungal agent in treating skin allergies, as well as in the preparation of polymers, rubber, and other materials. Recent research has focused on incorporating sulfur compounds into the synthesis of organic compounds because of their high stability in …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 31–43 Read article
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Managing Blow-by in Modern Engines: A Comprehensive Review of Crankcase Ventilation Technologies
Abstract: Blow-by in internal combustion (IC) engines occurs when high-pressure combustion gases escape past the piston rings into the crankcase. These gases typically carry oil aerosols, unburned hydrocarbons, and fine particulate matter, which, if not effectively managed, can disrupt lubrication, accelerate component wear, and contribute to harmful emissions. Effective crankcase ventilation is therefore essential not only for ensuring engine durability but also for meeting increasingly stringent emission regulations. This paper examines …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 317–324 Read article
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Bioinspired Nanocomposite Bone Pins: Fabrication, Evaluation, and Suitability for Orthopedic Implant Applications
Abstract: Bone tissue engineering (BTE) requires scaffolds that mimic bone’s mineral–organic composition, offering mechanical strength, bioactivity, and degradation rates compatible with regeneration. Conventional metallic implants face corrosion and toxic ion release risks, while ceramics like hydroxyapatite (HAp) are bioactive but brittle. This study reports a multifunctional hybrid scaffold combining HAp for osteoconductivity; polycaprolactone (PCL) and collagen for flexibility and biocompatibility with sodium citrate for nanoparticle dispersion, ferrocene (Fc) for catalytic bioactivity; …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 526–540 Read article
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Leveraging Industrial Waste for Green Sustainable Nanobiopolymer Synthesis: Polymer, Environmental, Legal and Global Arbitration Perspectives
Abstract: Nanobiopolymers can be synthesized from industrial waste using innovative methods, marking a forward-looking and ecologically sound step in production methods address to his Home State Industrial waste has been used conventionally either through incineration, landfilling or stabilization. It results in large environmental risks, including air, water and soil pollution and often involves costly stabilization and disposal. With the help of polymer and composite substance recovering value means life for current …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 705–711 Read article
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A Research on Goat milk and Papaya Face Wash
Abstract: The increasing demand for natural and sustainable skincare products has driven interest in bio-based cosmetic formulations. This study focuses on the development and evaluation of a goat milk and papaya–based face wash aimed at providing gentle cleansing, moisturizing, and exfoliating properties through natural ingredients. Goat milk, rich in lactic acid, proteins, and essential fatty acids, contributes to hydration and mild exfoliation, while papaya (Carica papaya) extract, containing papain enzyme and …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 30–38 Read article
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Development of Polymer Based SRAM Cell with Enhance Low Power Performance
Abstract: Low-power memory technologies are in high demand with the rapid growth of portable electronics and energy-efficient computing systems. Static random-access memory (SRAM) plays a crucial role in processors, cache memories, and system-on-chip applications due to their speed and reliability. Static Random Access Memory (SRAM) is typically implemented using complementary MOS (CMOS) technology, which integrates both PMOS (P-channel Metal–Oxide–Semiconductor) and NMOS (N-channel Metal–Oxide–Semiconductor) transistors. However, as technology scales to deep submicron …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1439–1448 Read article
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Investigation on The Effect of Carbon Fiber Reinforcement on The Mechanical and Physical Properties of FDM 3d Printed PLA
Abstract: In this work, the effects of annealing on the physical properties and mechanical behavior of short-carbon-fiber-reinforced polylactic acid (CF/PLA) composites made using fused deposition modeling (FDM) are systematically investigated. Pristine PLA and CF/PLA composites with 10% fibers have been made and evaluated in accordance with ASTM standards. Tensile, bending, and hardness tests were used to evaluate the performance of as-received and annealed composites. The tensile and hardness properties of PLA …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 284–298 Read article
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Formulation And Evaluation of Peel Off Mask From Custard Apple
Abstract: Herbal cosmetics have a long history of use aimed at enhancing cosmetic appearance and mitigating skin conditions such as acne, pigmentation, dryness, and wrinkles. These products provide various health benefits, including anti-acne, anti-inflammatory, moisturizing, antioxidant, and anti-aging effects, while also minimizing the risk of adverse reactions. Herbal formulations have gained global popularity and acceptance due to their natural origin, safety, and effectiveness in maintaining skin health. Traditional Indian herbs, like …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 6–15 Read article
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Optimization of Machining Parameters of EN-27 Material Using Wire Electric Discharge Machining (WEDM)
Abstract: The optimization of Wire Electrical Discharge Machining (WEDM) parameters for EN-27 alloy steel, a high-strength material widely utilized in mechanical and structural applications, is the subject of this study's methodical analysis. Due to its hardness and poor machinability by conventional methods, WEDM is preferred for achieving precise dimensional accuracy and surface integrity. The primary objective of this work is to enhance machining performance by identifying optimal process parameters influencing Material …
Published in Journal of Production Research & Management · Vol. 16, Issue 1, 2026 · pp. 32–36 Read article
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Optimized Machine Learning Framework for Battery State Prediction in Smart Charging Systems
Abstract: Good estimation of battery states, including State-of-Charge (SoC), State-of-Health (SoH), and Remaining Useful Life (RUL), are important in managing energy wisely and controlling the adaptive charging. This work introduces a streamlined machine learning model based on the ability to use multi-dimensional sensor measurements in terms of voltage, current, temperature, and cycle number to forecast battery conditions with high accuracy. Decent preprocessing, such as noise elimination, feature scaling, and calculated features, …
Published in International Journal of Energy and Thermal Applications · Vol. 4, Issue 1, 2026 · pp. 11–23 Read article
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Modeling and Simulation of a Grid-Connected Solar-Wind Hybrid Renewable Energy System with Controlled Inverter
Abstract: Solar and wind energy offer eco-friendly and renewable options to conventional energy sources, holding great promise for the future. This research delves into the modeling and simulation of a grid-connected solar-wind hybrid renewable energy system employing a controlled inverter. The study examines the individual photovoltaic (PV) and wind energy conversion systems and investigates their seamless integration to create a powerful hybrid generation system. To maximize energy use, the application of …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 22–32 Read article
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Bridging Brain-Inspired Learning and Quantum Reasoning for Future AGI Systems
Abstract: This research paper presents a novel neuromorphic–quantum hybrid computing framework envisioned to advance intelligent systems toward artificial general intelligence. The architecture integrates brain-inspired spiking networks for adaptive, energy-efficient learning with quantum processors for non-classical optimization and reasoning. A shared synaptic–quantum memory layer enables dual information representation, while neuromorphic adaptive controllers provide real-time stabilization of noisy quantum circuits. While quantum processors offer features like superposition- enabled exploration and entanglement-based correlations that …
Published in Current Trends in Signal Processing · Vol. 16, Issue 1, 2026 Read article
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Design and Development of a Mini Drone for Educational Applications
Abstract: This paper describe the complete process of designing, building, and testing a small unmanned aerial vehicle (UAV), normally referred to as a drone. The plan combines key concept from aerodynamics, electronics, control engineering, and embedded programming to produce a functional sample. The drone was developed using trivial structural materials and affordable components, including brushless DC motors, electronic speed controller (ESCs), a flight controller, various sensors, and a lithium-polymer (Li-Po) battery. …
Published in Journal of Aerospace Engineering & Technology · Vol. 16, Issue 1, 2026 Read article
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Development of Biodegradable Poly (Lactic-Co-Glycolic Acid) (PLGA) Nanoparticles for Sustained Release of Insulin
Abstract: This research outlines the creation of biodegradable composite nanoparticles made from poly (lactic-co-glycolic acid) (PLGA) designed for the sustained release of insulin. The emphasis is on the interactions between the polymer and the drug at the interface, along with the dynamics of the release matrix. The in vitro release kinetics, surface morphology, encapsulation efficiency, particle size, and polydispersity of insulin-loaded PLGA nanoparticles were analyzed following their production via a double …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1690–1699 Read article