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1068 articles for “selectivity”
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Failure Analysis of Hybrid Natural/Synthetic Fiber Composite Laminates in The Application of Hybrid Composite Pressure Vessel
Abstract: Composite laminates are frequently utilized in multiple sectors. The growing complexity of composites in aircraft applications necessitates hybridization of these materials. These hybrid laminates consist the combination of one natural fiber and two selected synthetic fibers. This work investigates three different six-layer hybrid composite laminate combinations: Jute2/Carbon2/Jute2, Jute2/Glass2/Jute2, and Carbon2/Glass2/Carbon2, with helix angles of 0° and 90° and a volume fraction of 50% fiber content. Each specimen is fabricated utilizing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 85–98 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Assessing the Impact of Chlorhexidine Mouthwash on Radiation-Induced Oral Mucositis in Head and Neck Cancer Patients: A Pre-Experimental Study
Abstract: Introduction: Cancer poses a major global health threat and is the second leading cause of death worldwide, following cardiovascular diseases, particularly in developed countries. Among cancers, head and neck cancer ranks as the 6th most common, representing about 6% of all cancer diagnoses. One of the frequent side effects of radiotherapy (RT) is mucositis, an inflammation of the mucous membranes. Chlorhexidine, a commonly used antiseptic and disinfectant found in mouthwashes, …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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Development of a Sustainable Mini Powerhouse for a Micro Steam Power Plant
Abstract: This study outlines the steps taken to sustain and relocate a mini powerhouse for a 5 kW steam power plant, addressing previous structural and environmental inefficiencies. Due to corrosion, instability, and inadequate thermal management at the original site, a new location was selected and reinforced to meet these challenges. Key changes included site preparation involving granites and other structural support materials, enhanced thermal insulation, and improved ventilation systems. Performance evaluations …
Published in Trends in Machine design · Vol. 12, Issue 1, 2025 · pp. 20–29 Read article
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Design, Analysis, and Testing of a Carbon Fibre-based Solid Rocket Motors
Abstract: The goal of the research is to simulate the outer shell of a rocket in order to fulfil mission criteria. Case failures can occur for a number of causes, including poor material selection, carelessness in the service conditions, inadequate non-destructive testing during crucial stages of production, and poor design and analysis. For this reason, it is crucial to simulate rockets with precise design and analysis. The study entails the designing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 650–669 Read article
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Effectiveness of Sustainable Design and Costing Practices in Construction: A Cross-Sectional Survey of Professionals’ Roles Towards Resource Conservation
Abstract: Climate change and the continuous depletion of natural resources have significant implications for the built environment. Sustainable construction has thus become topical, with measures being widely discussed on how to integrate it into proposed product design development, necessary to ensure resource conservation. This study evaluates the role of built environment design and costing professionals in sustainable construction, exploring their contributions towards resource conservation, and their effectiveness in implementing sustainable practices …
Published in International Journal of Industrial and Product Design Engineering · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Implementing Machine Learning in Data Classification
Abstract: Data classification forms an essential aspect of artificial intelligence (AI) and soft computing, helping a great deal in the transformation of raw data into knowledge that forms the basis of numerous applications, such as fraud detection, medical diagnostics, and natural language processing. This study discusses the challenges and the state of the art in data classification, as far as scalability, noise handling, and feature selection optimization are concerned. It gives …
Published in International Journal of Data Structure Studies · Vol. 3, Issue 2, 2025 · pp. 15–22 Read article
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A Comprehensive Study on Improving Contact Lens Performance Through Various Approaches
Abstract: Contact lenses improve vision quality by correcting refractive errors and thus provide a convenient alternative to traditional eyeglasses. Apart from vision enhancement, they have multiple applications in cosmetics, drug delivery, and therapeutic use. The performance of these lenses depends on various factors such as material, design, fitting, and interaction between the lens and the eye. The selection of appropriate materials is crucial for maintaining optimal eye health. Properties like oxygen …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 211–222 Read article
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Optimizing Sampling Techniques Using Fuzzy Set Theory: A Comprehensive Approach
Abstract: Sampling is a critical process in statistics, used to estimate population parameters without needing to examine the entire population. Traditional sampling methods, such as simple random sampling, stratified sampling, and cluster sampling, face limitations when applied to complex or heterogeneous populations with imprecise boundaries. These methods often fail to accurately represent populations with overlapping characteristics or missing data, resulting in sampling bias and reduced accuracy. To address these challenges, this …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 1, 2025 · pp. 29–43 Read article
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Advances in Polymer-Based Nanocomposites for Moisture-Sensitive Applications
Abstract: Polymer-based nanocomposites have emerged as promising materials in sensor technology due to their superior mechanical, electrical, and environmental stability. These advanced materials offer unique advantages, such as enhanced sensitivity, durability, and adaptability to various environmental conditions, making them highly suitable for sensor applications. One of the most significant breakthroughs in this field is the integration of semiconducting nanoparticles (NPs) within a polymer matrix, which has led to remarkable improvements in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 145–152 Read article
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Self-Healing Polymer Composites for Pharmaceutical Packaging Applications
Abstract: Pharmaceutical packaging plays a crucial role in ensuring the safety, stability, and effectiveness of pharmaceutical products. Conventional polymer-based packaging materials are prone to mechanical damage, microcracks, and environmental degradation, which can compromise drug integrity. Self-healing polymer composites (SHPCs) offer a promising solution by enabling autonomous or stimuli-responsive repair mechanisms that restore packaging integrity, enhance durability, and extend product shelf life. These materials function through intrinsic mechanisms, such as dynamic covalent …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 648–658 Read article
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Neuroimaging in Clinical Trials for Huntington’s Disease: Emerging Research Findings: The Advancement Directions and Implications
Abstract: Neuroimaging is very important in coordinating and conducting Huntington’s disease clinical trials as a tool in selecting patients, managing safety concerns, and assessing the benefits of interventions. This review presents the current uses and potential future uses of structural and functional magnetic resonance imaging (MRI), diffusion imaging, positron emission tomography (PET), proton magnetic resonance spectroscopy (MRS), perfusion imaging, and magneto encephalography (MEG) in HD trials. We describe how these modalities …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 32–44 Read article
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Design and Development of Pipe Bending Machine
Abstract: The design and development of a pipe bending machine are crucial for various industrial applications, including the construction, automotive, and manufacturing sectors. Bending is a fundamental metalworking process that involves deforming pipes, tubes, square hollows, and rods without compromising their structural integrity. This study focuses on designing a cost-effective and efficient pipe bending machine that can accommodate different pipe sizes and materials. The key design considerations include selecting an appropriate …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 1, 2025 · pp. 22–30 Read article
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A Study on Heavy Metal Contamination in Workers Handling Electronic Waste in North India
Abstract: Background E-waste contains hazardous substances like leads, cadmium, mercury, and arsenic which can be harmful for informal workers and recyclers. In North India, one finds an informal sector of e-waste workers who work in extremely micro-manageable conditions with lack of order policy and protective equipment. This study explores the processes and cavities of heavy metals as well as assessing the knowledge, safety measures, and health symptoms of the reclaimers. Objectives …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Innovative Polymer Membranes for Enhanced Gas Separation: Applications in Energy and Environmental Technologies
Abstract: Energy and environmental technology could benefit greatly from novel gas-separation membranes, especially those based on new polymers. This includes the design and characterization of new polymer membranes with enhanced selectivity and permeability for critical industrial gas separations like CO₂/CH₄ as well as CO₂/H₂. Using molecular design strategies, the membranes are addressed toward properties relevant for gas transport, which are important for applications that include carbon capture, natural gas purification, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Tribological Behaviour of PTFE based Composite Materials with Different Filler Materials: A Combine Numerical and Experimental Approach
Abstract: This study investigates the tribological behaviour of Polytetrafluoroethylene (PTFE) composites reinforced with various fillers, utilizing the Archard wear model to analyse wear mechanisms and predict wear rates. PTFE is widely recognized for its excellent chemical resistance and low friction, but its inherent wear resistance is relatively poor. To enhance its tribological properties, fillers such as glass fibres, carbon fibres, bronze, and graphite were incorporated into the PTFE matrix. In the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 547–557 Read article
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Evaluating Chassis Designs for Gesture-Driven Robots: A Study of Iron, Acrylic, and 3D Printed Solutions
Abstract: Gesture-driven robotic systems are becoming increasingly relevant in applications such as assistive technology, industrial automation, and interactive systems. The choice of chassis material plays a crucial role in determining the robot's mechanical strength, weight, and ease of fabrication. This study systematically evaluates three chassis materials—iron, acrylic, and 3D printed polymers—to determine their suitability for gesture-controlled robots. A standardized robotic configuration, including two rear motors, two front dummy axles, an L298N …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 686–692 Read article
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Dental Implant Analysis Using the Wear and Hardness Testing Method
Abstract: We will compare the number of implants from the manufacturer using either an analytical approach or a software-based approach using Minitab software regarding structural dental implants. Several factors influence a dental implant, and new bone grows. The implant surface is one of the elements that have a major impact on the quality of osteointegration. Various techniques and resources have been employed to modify an implant's surface to encourage osseointegration along …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article