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532 articles for “quantum mechanics/molecular mechanics (QM/MM)” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Prototype Model Development and Design Analysis of A Solar Tricycle for Physically Challenged People in India
Abstract: Society is greatly concerned about the mobility of individuals with physical disabilities. The scarcity of energy resources and the issue of pollution are currently the primary concerns. These issues can be resolved by employing alternative energy sources such as solar power. This paper presents an overview of the existing solar tricycles designed for those with disabilities. It also improves a handicapped-friendly solar-powered tricycle. The goal is to reduce handicapped people's …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 43–56 Read article
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Problems and Difficulties in the Additive Manufacturing of Composites with Carbon Fiber Reinforcement for Medical Application
Abstract: Amputation is more prevalent than one may think due to an accident, war, or disease. Prosthetics and associated orthotics have a combined global market value of $2.8 billion. Carbon fibre has found a market due to increased demand for foot prostheses. Fused deposition modeling (FDM) is a rapidly advancing three-dimensional (3D) printing technique. PEEK (polyether-ether-ketone) is a biocompatible, high-performance polymer that could potentially be utilised as an orthopedic surgery implant …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 8–12 Read article
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Suitability of Stone Dust as an Alternative Aggregate in Asphalt Mixtures Using Rothfuch’s Method of Aggregate Combination
Abstract: The increase in pollution across the globe is one crucial area requiring mitigation. The bye product of quarries can pose great health and environmental risks. Construction industries in Nigeria heavily relies on conventional asphalt aggregate for construction of road pavements. This is one area of interest as mineral fillers and different aggregate gradations have a great effect on the mechanical property of asphalt concrete pavements. Stone dust is obtained from …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Reusable Plastic Advantages, Challenges, and Impacts on Waste Management and Conservation Efforts
Abstract: The widespread utilization and ill-advised removal of single-use plastics have prompted critical natural contamination and asset consumption. Accordingly, society is progressively looking for supportable other options, with reusable plastic arising as a promising arrangement. This exploration paper intends to dig into the idea of reusable plastic, investigating its advantages, difficulties, and likely effect on squander the executives and preservation endeavors. Drawing on existing writing, contextual investigations, and mechanical progressions, the …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 1, 2024 · pp. 14–22 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Periodontitis and Rheumatoid Arthritis
Abstract: This comprehensive review delves into the complex interplay between Periodontitis and Rheumatoid Arthritis, aiming to unravel the underlying mechanisms and shared inflammatory pathways that connect these seemingly distinct conditions. The review examines a wealth of current research, exploring how chronic periodontal inflammation may contribute to the development and progression of RA and vice versa. Furthermore, the review critically evaluates the clinical implications of this interrelation, emphasizing the need for interdisciplinary …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 31–39 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article
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Effectiveness of Temporins for the Treatment of HPV Infections
Abstract: Objectives: Human papillomavirus (HPV), especially high-risk variants like type-16 have been linked to the formation of malignant tumors. HPV-16 has been implicated in most cases of cervical cancer in women. This study aims to assess the effectiveness of three types of temporin molecules, i.e., antiviral peptides secreted by certain frog species, for the inhibition of the viral L1 protein. Methods: In the present study, various computational tools were used to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 41–53 Read article
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Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
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Human Deep Skin Surface Vibration Frequency Detection from CT and DT Signals Using Genetic Algorithms
Abstract: To diagnose respiratory problems early on, a contactless, non-invasive, real-time assessment of human vibration is a crucial prerequisite. Optoelectronic plethysmography (OEP) and the forced oscillation technique (FOT), are two widely utilized methodologies, depending on variations in each patient’s local chest impedance. Calibration of the devices before each measurement is hence the primary problem of these approaches. This report presents a simulation-based analysis to assess the effectiveness of the CT and …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 2, Issue 1, 2024 · pp. 9–16 Read article
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A Review Paper on Friction Stir Processing on Aluminium Alloys
Abstract: Friction stir processing is a step from friction stir welding, targeted at surface modification through improving the local microstructure via localized plastic deformation. The tool consists of a rotating mechanism incorporating a shoulder and pin that are inserted into the material, traversing the designated area. When the tool's shoulder and the workpiece make contact, friction develops, generating heat that produces plastic deformation. This localized plastic deformation and heat impact result …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Heterocyclic Substituted Flavones: Bridging Natural Products and Medicinal Chemistry
Abstract: Heterocyclic substituted flavones represent a unique and promising class of flavonoid derivatives, gaining significant attention in recent years due to their diverse and enhanced biological activities. These compounds are characterized by the incorporation of heterocyclic moieties such as quinoline, pyridine, thiazole, imidazole, oxazole, and pyrazole into the flavone structure, which significantly alters and often enhances their bioactive properties. This structural modification has made heterocyclic flavones particularly appealing as candidates for …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 23–30 Read article
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Direct Synthetic Routes of MXenes and Their Application in Carbon Fiber Reinforced Plastics (CFRPs) As Supplementary Sizing Layer†
Abstract: Sized carbon fibers with a supplementary sizing layer of MXenes (synthesized via traditional MAX phases), bonded to carbon fibers (CFs) as well as the resin matrix via different kinds of physicochemical (van der Waals force, hydrogen bonding, covalent bonding) interactions enhanced the performance of the resulting carbon fiber reinforced plastic (CFRP) materials. This is because of the strong interface generated due to the appearance of MXene at the interface of …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 07–13 Read article
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Synthesis, Characterization, and Reactivity of Bivalent Tin(II) with 4-Tert-butylphenol
Abstract: Bivalent tin(II)-4-tert. butylphenoxide of composition Sn(OC6H4X-4)2(I), where X = But, has been synthesized by the reaction of stannous chloride (SnCl2) with bimolar amounts of 4-tert. butyl phenol (HOC6H4But-4) in the presence of the base, diethyl amine, in tetrahydrofuran (THF) solvent. The resulting complex was characterized by elemental analysis, molecular weight determination, molar conductance measurement, IR, and 1H NMR spectral studies. The reactivity of the newly synthesized complex (I) with HgCl2 …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 14–19 Read article
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Resolving International Sports Disputes: An Exploration of Mediation and Conciliation
Abstract: The globalization of sports has led to an increase in cross-border disputes, necessitating effective and efficient dispute resolution mechanisms. Traditional litigation and arbitration methods often prove time-consuming, costly, and ineffective in preserving relationships. This research explores the role of Alternative Dispute Resolution (ADR) methods, specifically mediation and conciliation, in resolving international sports disputes. Through a comparative analysis of international sports organizations and dispute resolution mechanisms, this study examines the benefits …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 14–27 Read article
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SiRNA-Based Multivalent Vaccines: A Systematic Review of Potential Risks, Benefits, and Future Applications
Abstract: Background: Small interfering RNA (SiRNA) technology represents a promising innovation in vaccine development, especially for multivalent vaccines that can target multiple pathogens or antigenic variants simultaneously. siRNA-based vaccines offer a unique mechanism to induce specific immune responses, presenting an adaptable and potentially powerful tool for tackling infectious diseases and cancer. Methods: This systematic review synthesizes recent studies on siRNA multivalent vaccines, focusing on their immunogenicity, safety, and effectiveness. We reviewed …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 43–49 Read article
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Cyberattack Detection and Prevention Using Empowering AI Tools
Abstract: With more organizations entering the digital transformation sphere, the opportunities and risks in cyberspace have increased and gone up in levels of sophistication and occurrence. Many of these developments are attributed to the limits of existing cyber security solutions where addressing new threats requires advanced detection technologies and techniques. Cyber threats gained a new meaning and dimension with artificial intelligence (AI) coming into play in ways that supplement security systems …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Approach to Examine the Effect of Atomic Number on Single – Electron System of Group III Elements
Abstract: This study investigates the ionization energy, kinetic energy, and mass relationships among Group III elements (Boron, Aluminum, Gallium, Indium, and Thallium) to provide a comprehensive understanding of their atomic and physical properties. A detailed analysis of ionization energy trends reveals that Boron exhibits the highest ionization energy, while Thallium has the lowest, consistent with periodic trends influenced by increasing atomic radius and electron shielding. Gallium deviates slightly from this trend …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 01–09 Read article
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Innovative Porcelain Insulators: Prolonged Durability and Anti-Contamination Efficiency via Nano-TiO2 Photocatalyst Integration
Abstract: Porcelain has long been a critical material in high-voltage electrical insulation due to its exceptional mechanical, thermal, and dielectric properties. However, environmental contamination and material degradation over time pose significant challenges to its durability. This study investigates the integration of nano-sized titanium dioxide (TiO2) photocatalyst coatings on porcelain insulators to enhance their performance and prolong their operational lifespan. Local clay compositions were analyzed, and a comparative study of untreated and …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 18–23 Read article
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Optimizing Fin Parameters to Enhance Passive Heat Dissipation in Photovoltaic Panels
Abstract: This study explores passive cooling techniques to enhance the thermal management of photovoltaic (PV) modules, which is crucial for maintaining efficiency. A computational fluid dynamics (CFD) model, using ANSYS Fluent, was developed to evaluate three fin shapes: rectangular, trapezoidal, and triangular, attached to the back of PV modules. The study varied parameters such as fin count, thickness, and length to determine optimal configurations for cooling. Among the designs, triangular fins …
Published in International Journal of Radio Frequency Innovations · Vol. 2, Issue 2, 2024 · pp. 25–35 Read article