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307 articles for “gene regulation”
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Optimizing Airline Efficiency Using Big Data and Predictive Analytics
Abstract: Recent technological advancements have resulted in the generation of vast volumes of data across industries, including the airline sector, supporting operational control and service quality. Big Data Analytics (BDA) enables organizations to analyze large and complex datasets to derive actionable insights that support informed decision – making and superior operational performance. This review paper systematically analyzes twenty relevant research studies to explore the application of Big Data Analytics (BDA) within …
Published in Journal of Advanced Database Management & Systems · Vol. 13, Issue 1, 2026 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Significant Advances in Cloud Computing in Information and Communications Technology
Abstract: The critical advances in information and communications technology (ICT) over the last half-century have led to the increasingly common vision that computing will one day become the 5th utility. This computing utility will provide the essential level of computing service considered basic to meet the everyday needs of the general public. To convey this vision, a number of computing models have been proposed, with the most recent being cloud computing. …
Published in Recent Trends in Parallel Computing · Vol. 11, Issue 3, 2024 · pp. 33–38 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Sustainable Water Management in Engineering: Identifying Causes and Implementing Solutions
Abstract: Water is a vital resource in engineering applications, underpinning processes in manufacturing, construction, power generation, and environmental systems. Unsustainable water consumption and waste, however, present serious problems, such as resource depletion, environmental damage, and higher operating expenses. This paper explores the causes of water waste in the engineering sector, such as inefficient processes, aging infrastructure, and inadequate wastewater management, alongside the impacts on economic performance and ecological balance. To address …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 9–26 Read article
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Molecular Docking Studies of Wildtype P53 with Damnacanthal and Scopoletin- Phytochemicals Derived from Morinda Citrifolia
Abstract: Cancer is a prominent cause of mortality globally, and it has the potential to impact any region of the body. The tumor suppressor protein P53 plays a significant role in inhibiting tumor growth by regulating DNA repair, inducing cell cycle arrest, promoting senescence, and triggering apoptosis when confronted with genotoxic stress. P53 is found mutated in 50% of cancers where it loses its tumor suppressive properties and gains oncogenic properties …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 20–31 Read article
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Perception and Implementation of Sports Safety Measures Among University Physical Education Instructors in Punjab: A Cross-Sectional Study
Abstract: Introduction: Considerable attention must be focused on sports safety as it is a constituent of thephysical education (PE) curriculum at the university level, in view of the frequent and vigorous engagement in physical activities. While there is general acknowledgement of the existence of safetymeasures, the extent to which such measures are put into practice may differ. This research examines the perceptions and practices related to sports safety of university PE …
Published in Recent Trends in Sports · Vol. 2, Issue 2, 2025 · pp. 45–55 Read article
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A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
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Disaster Management for the Production Process in Manufacturing Industries
Abstract: In manufacturing and businesses in general, damages occurring during production must be recorded. Production is carried out continuously every day through various processes that make up the supply chain. This process is often ineffective and causes damage. These disasters cause economic damage and losses, sometimes even death. These damages may result from accident, negligence or incompetence. There are other things around. This article focuses on damage elements associated with the …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 1, 2026 · pp. 16–19 Read article
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Strengthening Low Voltage Ride-Through in Wind Energy Systems: A Comparative Study of DVR and STATCOM
Abstract: This study looks at the various methods used to improve the low-voltage ride-through (LVRT) capabilities of wind turbine systems (WT) that are based on double-fed induction generators (DFIG). The Type-III WT machine, which is mostly based on DFIG, is instantly connected to the grid without the digital power interface, making the terminal voltage or reactive electricity output unmanageable. This is because the world utilizes between 20% and 25% of renewable …
Published in Journal of Power Electronics and Power Systems · Vol. 14, Issue 3, 2024 · pp. 47–62 Read article
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Solar Panel Maintenance and Prevention System
Abstract: Solar energy has emerged as a sustainable and efficient alternative to conventional energy sources. However, maintaining solar panels is crucial to ensure optimal performance and longevity. Accumulation of dust, dirt, and environmental debris can significantly reduce energy efficiency, leading to increased operational costs and potential system failures. To overcome this issue, we suggest an IoT- based Solar Panel Maintenance and Prevention System that facilitates automated cleaning and preventive maintenance via …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 16, Issue 2, 2025 · pp. 29–34 Read article
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Remote Controlled Boat for Water Pollution Monitoring
Abstract: The global issue of water quality degradation caused by pollution has become a critical environmental concern. Leaving water unchecked for an extended period make it unfit for human needs and eradicate the entire water ecosystem. Water being considered as a vital element in sustaining living things need to be protected. To address this challenge, novel technological solutions are being devised to effectively monitor and manage water resources. This study introduces …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 34–43 Read article
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Design and Implementation of a Real-Time ANPR-OCR Based Embedded System for Automated Vehicle Compliance Verification-Checking Valid PUC and Insurance
Abstract: With the rapid increase in vehicle ownership, ensuring adherence to traffic regulations has become essential, particularly concerning vehicle insurance and Pollution Under Control (PUC) certification. Non-compliance with these requirements can lead to financial risks, legal violations, and environmental damage. Traditional enforcement methods rely on manual inspections, which are time-consuming, inefficient, and prone to human error. To address these challenges, this paper proposes an automated system that utilizes Automatic Number Plate …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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A Comprehensive Review on the Miniaturized Analytical Techniques for Sustainable Pharmaceutical Testing
Abstract: Miniaturized analytical techniques are revolutionizing pharmaceutical testing by offering sustainable and efficient alternatives to traditional methods. These techniques are designed to reduce sample and reagent consumption, minimize waste generation, and accelerate analysis, aligning perfectly with the principles of green analytical chemistry. This comprehensive review aims to thoroughly explore the landscape of miniaturized analytical techniques, specifically highlighting their profound impact on fostering sustainable practices within the pharmaceutical sector. The review systematically …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 18–39 Read article
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AI-Accelerated Development of Gradient Polymer Nanocomposite Thin Films
Abstract: Gradient polymer nanocomposite thin films are an active field of materials research due to the fact that it enables scientists to de-facto regulate the optical, electrical, and mechanical properties of a film by merely altering its composition on a layer-by-layer basis. This type of control opens the gate to the improved flexible electronics, long lasting protective coats, and the new smart gadgets. The problem is, though, that it is a …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 456–469 Read article
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Indian Entrepreneurs' Role in E-Commerce
Abstract: The e-commerce industry in India has experienced unprecedented growth as a result of the rapid penetration of the internet, the availability of affordable telephones, and the shifting behaviors of consumers. Using technology, ingenuity, and locally tailored solutions, Indian businesspeople have been at the forefront of this transformation, which has enabled them to serve a massive and varied market. An examination of the ways in which Indian e-commerce firms have triumphed …
Published in E-Commerce for Future & Trends · Vol. 12, Issue 2, 2025 · pp. 01–15 Read article
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Advanced Helmet Recognition System with Integrated Number Plate Detection for Enhanced Traffic Monitoring Using Deep Learning
Abstract: This study focuses on the crucial problem of non-adherence to traffic regulations, particularly with the compulsory use of helmets by motorcyclists. Motorcycle accidents have a greater mortality rate compared to other types of accidents, indicating a need for a more effective enforcement strategy. Current procedures depend on traditional techniques where traffic officers manually observe traffic rule infractions through patrols and monitoring CCTVs, requiring substantial labor and time resources. The inherent …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 2, Issue 1, 2024 · pp. 9–18 Read article