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421 articles for “Uses Pharmacological”
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Review on Drug Nanoparticles: Special Emphasis on Herbal Nanoparticals
Abstract: Nanoparticles have greater research horizon and smaller size ranging from 1 to 1000 nm. This is very small as compared to other particles. As their size is extremely small, so ultimately their route of administration and reaching to site of action becomes more convenient. These nano-scale particles can easily pass out the cell membrane such as blood brain-barriers. Nanoparticles are synthesized from various metals, polymers, microbes and even from plant …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 48–58 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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A Review on: Cotard’s Syndrome
Abstract: Cotard’s Syndrome is a rare and severe mental health condition characterized by nihilistic delusions, in which individuals firmly believe that they are dead, no longer exist, or that parts of their body are decaying or missing. These beliefs are not symbolic or metaphorical but are experienced as absolute truths, making the disorder particularly distressing and difficult to manage. The syndrome is most commonly observed in association with major depressive disorder, …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 5–9 Read article
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Homeopathy: The Evidence and Basis of Physiological Medicine
Abstract: AbstractIt is time we looked at a fresh, new scientific model for homeopathic remedy action on living systems — one that is logically and rationally based. A paradigm that explains why homeopathy is scientifically “plausible” and how homeopathic remedies exert their biological effects primarily as nanostructures and why physiology, not pharmacology, is the most appropriate discipline for studying and validating the credo. This is imperative to bring two sequels to …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 3, Issue 3, 2014 · pp. 11–18 Read article
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Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System
Abstract: Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography. Keywords: Derivatization, amino acid, chiral reagent, HPLCCite this Article Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 39–43 Read article
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Killer of the Killer—Myeloperoxidase Inhibitor from Siddha System of Medicine
Abstract: Two proprietary siddha medicines such as NiKu plus and S.I.V.A. herbal drops were evaluated for myeloperoxidase (MPO) inhibition by in vitro enzyme assay. The MPO plays an important role in the predisposition of various complications both in diabetes mellitus (DM) and in psoriasis. Both NiKu plus and S.I.V.A. herbal drops showed high inhibitory activity of MPO. The findings suggest that regular use of NiKu and S.I.V.A. is must for patients …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 8, Issue 3, 2018 · pp. 31–34 Read article
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Effect of Valsalva Maneuver Prior to Cannulation on Pain Among Patients Undergoing Peripheral Venous Cannulation
Abstract: Peripheral venous canulation is the common nursing procedure carried out which cause soreness to the recipient. Previous experience of peripheral venous cannulation may result in negligence or delay in need of medical care. Valsalva Maneuver is a non-pharmacological and cost- effective method to decrease intensity of pain during peripheral venous cannulation. Aim: To assess the effect of Valsalva Maneuver prior to cannulation on pain among patients undergoing peripheral venous cannulation. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 1–6 Read article
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Use of NMR and Other Spectroscopy Techniques in Heterocyclic Oxadiazole Derivatives Studies: A Review
Abstract: It was possible to create a number of novel symmetrical 2,5-dialkyl-1,3,4-oxadiazoles with substituents including carboxymethylamino, isopropyloxycarbonylmethylamino, and bromine at the terminal positions of the alkyl groups. The multistep process that was devised used hydrazine hydrate, phosphorus oxychloride, and commercially available acid chlorides that varied in alkyl chain length and terminal substituent.Diisopropyliminodiacetate was an easy way to substitute the intermediate bromine-containing 2,5-dialkyl-1,3,4-oxadiazoles. This was followed by hydrolysis in an aqueous methanol …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 07–13 Read article
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A Comprehensive Review on Therapeutic Potentials of Patha (Cissampelos pareira Linn.) from Classical Texts of Ayurveda
Abstract: Patha is one of the widely used medicinal plants since Vedic period. In classical texts, the plant is also cited as an edible leafy vegetable apart from its medicinal properties. Patha is indicated in the treatment of various disease conditions as a single drug and as an ingredient of many compound formulations. In the present review, comprehensive review of Ayurvedic classical plant Patha has been carried out from 25 Nighantus …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 17–35 Read article
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Treatment and management of Hypertension using Combinatorial therapy: A recent Approach
Abstract: One of the most frequent and widespread illnesses is hypertension. Nowadays, several medications are used to treat hypertension but are implicated in having some severe side effects. So, to overcome these side effects, there is the usage of a combination of drugs based on lesser side effects and an increase in efficacy or therapeutic goals. Although the first pharmacological therapy impacts long-term results, lowering blood pressure is the most critical …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 3, 2022 · pp. 1–7 Read article
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Pharmacological Management of Parkinson’s Disease: Current Therapies and Emerging Treatments
Abstract: Objective: Parkinson's disease, behind Alzheimer's, is the second most common neurodegenerative ailment and a major cause of neurological morbidity worldwide. Clinical diagnosis is made, and current management is limited to symptomatic treatments, with levodopa remaining the cornerstone of pharmaceutical therapy. In certain patient groups, deep brain stimulation of specific basal ganglia targets can provide significant clinical relief. There are currently no proven disease-modifying medicines in clinical use that can halt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 27–39 Read article
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Common Medicinal Plants and their Importance
Abstract: AbstractSince prehistoric times, many plant species are used as traditional medicine practices and those are called medicinal plants or medicinal herbs. Most of the plants around us are used traditionally as Indian folk medicine, either in Ayurvedic system or in Unani system of treatment. The extracts of these plants are used as herbal tonic and nowadays some are widely used in Homeopathy mode of treatment. Till date many plants have …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 1, 2020 · pp. 1–5 Read article
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Exploring the Connection between Mindfulness and Alzheimer's Disease/Parkinson's Disease: A Systematic Review and Meta-Analysis.
Abstract: Alzheimer's disease and Parkinson's disease have serious effects on patients and their families, yet there are no known treatments to slow the progression of these diseases. Non-pharmacological treatments for these problems, like yoga and meditation, have begun to gain popularity. The purpose of this meta-analysis and systematic review was to examine the relationship between yoga and mindfulness meditation and Alzheimer's and Parkinson's disease, as well as their potential to help …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 14, Issue 2, 2023 · pp. 1–9 Read article
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Review on Cyperus scariosus: A Potential Medicinal Plant
Abstract: Saad kofi or Cyperus scariosus, known as Nagarmotha in India, is a delicate grass which is an angiosperm belonging to family Cyperaceae. Indian species of this plant is called motha. The best quality of saad is heavy in weight, rough from outside with strong aroma, whitish inside, highly bitter in taste. Its root extracts and volatile oil are used for medicinal purposes. Nagarmotha is also prescribed by local herbal medicine …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 4, 2021 · pp. 28–32 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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Avicennia Marina (FORSK) Vierh: A Review On Its Medical Properties
Abstract: Current generation is a fast moving and no doubt about the strength of allopathic medicine, they provide quick result, but the darkest side of this medicine is their several side effects and contraindications. On the other hand the plants are good substitution for those medicines because of their less or no side effect and their capability to cure the trouble from their root. Our study is based on the pharmacological …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 1, Issue 1, 2011 · pp. 29–40 Read article
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Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 16–30 Read article