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412 articles for “PKA/CREB pathway”
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Autonomous Agent Contracts for Adaptive Supply Chains
Abstract: This paper proposes a novel agent-driven, on-chain coordination layer for manufacturer–distributor–retailer handoffs that automates release, transfer, receipt, and state validation across the supply network. This approach combines belief–desire–intention (BDI) agents with narrowly scoped smart contracts to capture role responsibilities, capacity checks, and escalation policies. It aims to enhance conformance, traceability, and cycle-time reliability without relying on central intermediaries. This proof of concept links supply chain states—such as production-ready, packaged, listed, …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 1, 2025 · pp. 52–60 Read article
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Polymers In Low-Resource Biomedical Innovation: Maker Labs, DIY Devices and Ethics
Abstract: The low-cost biomedical devices have been prototyped and sometimes put into practice by maker laboratories and community "DIY" (Do-It-Yourself maker) innovators due to the fast-growing availability of polymer-based fabrication (desktop 3D printing, laser cutting, and simple molding). Nowadays, polymers such as PLA, PETG, TPU, and PEEK are used in a wide range of applications, including surgical guides and anatomical models, as well as assistive technology and diagnostic housings. Such innovations …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 108–119 Read article
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Digital Frontiers in Life Sciences: The Transformative Role of Computing in Modern Biology
Abstract: The integration of computers in the biological sciences has revolutionized research and experimentation, facilitating advancements in areas such as genomics, bioinformatics, systems biology, and ecological modeling. The ability to process vast amounts of biological data efficiently has transformed how scientists study complex biological systems and phenomena. Computational tools enable the analysis of DNA sequences, protein structures, metabolic pathways, and ecological dynamics, which were previously beyond the reach of traditional laboratory …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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Engineered Hybrid Nanoclay-Infused Nano-Polymers for Multifunctional Anti-Corrosive Coatings
Abstract: Polymer nanocomposites reinforced with layered nanofillers have emerged as an effective route to enhance structural stability in protective coating applications. Polymer–clay nanocomposites also provide a promising route to enhance mechanical robustness and environmental durability in coating systems. In this study, a hybrid epoxy–polyurethane (EPU) coating was reinforced using organo-modified montmorillonite (o-MMT) and layered double hydroxide intercalated with 2-mercaptobenzothiazole (LDH–MBT). Uniform dispersion and interfacial anchoring between the nanoclays and polymer chains …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 40–53 Read article
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Magnetic Metal–Polymer Composites with Ferromagnetic Particle Networks for EMI Shielding in Flexible Electronics
Abstract: The rapid expansion of flexible and wearable electronic systems has intensified the demand for lightweight, mechanically compliant materials capable of effective electromagnetic interference (EMI) shielding. In this study, magnetic metal–polymer composites with magnetically aligned ferromagnetic particle networks were developed and systematically investigated for EMI shielding in flexible electronics. Thermoplastic polyurethane (TPU) was employed as an elastomeric polymer matrix due to its excellent flexibility, dielectric characteristics, and compatibility with particulate fillers. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 25–39 Read article
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Cancer Chemotherapy-Induced Cachexia: Bridging Mechanisms, Management, and Future Therapies
Abstract: Involuntary weight loss, skeletal muscle atrophy, adipose tissue depletion, anorexia, and systemic inflammation are all symptoms of chemotherapy-induced cachexia, a complex illness. Although it is common, it remains poorly understood and is often referred to as an "orphan disease." This study covers the epidemiology, pathophysiology, clinical symptoms, diagnosis, treatment, and emerging treatment options for chemotherapy-induced cachexia. To comprehend the causes, clinical results, and therapeutic approaches, a literature-based synthesis of recent …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 17–26 Read article
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Interaction of Mosquito’s hppd Enzyme with Lansoprazole Sulfide A New Hope to Tackle the Mosquito Menace – an in-Silico Study
Abstract: Tyrosine detoxification is an important physiological process that helps blood-feeding insects, such as mosquitoes that transmit Plasmodium parasites causing malaria, digest their blood meals. An enzyme known as 4-hydroxyphenylpyruvate dioxygenase (HPPD), which is part of the tyrosine detoxification pathway, helps in removing excess tyrosine in a high-protein blood meal. Excess tyrosine can be lethal to the insects, and hence, the role of HPPD enzyme is very critical. Inhibitors of HPPD …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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OBD-II Big Data–Driven ML and AI-Based Virtual Sensing for Fuel Economy, Component Health, and Carbon Intelligence
Abstract: The rapid growth of connected vehicles has led to the large-scale availability of high-frequency On-Board Diagnostics II (OBD-II) data; however, much of this data remains underutilised, as existing studies and commercial systems typically address fuel economy, maintenance, or emissions in isolation or rely on additional physical sensors. Such fragmented and sensor-dependent approaches limit scalability and increase system cost, particularly in high-volume and resource-constrained vehicle markets. To address this gap, this …
Published in Journal of Automobile Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 39–50 Read article
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Polymer Electrolyte Films Doped with Nanofillers ZnO: Electrochemical and Optical Investigations
Abstract: The electrochemical and optical characteristics of polymer composite electrolyte films doped with zinc oxide (ZnO) nanofillers are thoroughly examined in this work. Because of its superior film-forming capacity, flexibility, and ionic transport properties, poly(vinyl alcohol) (PVA) mixed with potassium iodide (KI) is used as the host polymer electrolyte. To investigate their effects on ionic conductivity, dielectric behavior, and optical transmission, ZnO nanoparticles are synthesized and added to the PVA–KI matrix …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 320–332 Read article
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Evaluation of CI Engine Performance and Emissions Using WB10CNT90: A CNT-Reinforced Biodiesel Blend Approach and its Marketing Prospects for sustainable fuel Commercialization
Abstract: The experimental and analytical evaluation of the WB10CNT90 blend—a combination of 10% waste biodiesel derived from Madhuca longifolia, 90% conventional diesel, and 100 ppm Multi-Walled Carbon Nanotubes (MWCNTs)—demonstrates its potential as an efficient and eco-friendly alternative to conventional diesel. The Brake Thermal Efficiency (BTE) of the engine increased by approximately 15%, indicating enhanced energy conversion efficiency during combustion. Simultaneously, the Brake Specific Fuel Consumption (BSFC) showed a reduction of nearly …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 741–759 Read article
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Nano Shield-EV: Graphene and CNT-Infused Polymer Composites for Advanced EMI Shielding in Electric Vehicles
Abstract: The rapid growth of electric vehicles (EVs) has intensified the need for lightweight, thermally stable, and mechanically robust electromagnetic interference (EMI) shielding materials to ensure the reliable performance of advanced electronic systems. Traditional metallic shields, though highly effective, increase vehicle weight and restrict design flexibility, thereby motivating the search for multifunctional polymer-based alternatives. In this study, NanoShield-EV introduces novel polymer nanocomposites fabricated via melt blending and compression molding, combining engineering-grade …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1036–1047 Read article
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Paternal Pre-Pubertal Smoking: Small RNAs, Lasting Marks, and the Hidden Legacy of Early Exposure
Abstract: While the negative effects of maternal smoking during pregnancy are well-established, the lasting and transgenerational impact of paternal pre-pubertal smoking remains a critical, underexplored area. Emerging evidence in sperm epigenetics suggests that cigarette exposure during early male development may create persistent molecular imprints that can affect the health of future offspring. This phenomenon is rooted in the fact that heredity extends beyond the DNA sequence. Sperm carry a complex epigenetic …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 1–5 Read article
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A Comparison of Different Generative AI Models
Abstract: Generative models have significantly advanced the field of artificial intelligence by allowing machines to produce complex and realistic outputs such as images, text, and other forms of data. Among the leading frameworks in this domain are generative adversarial networks (GANs), variational autoencoders (VAEs), and architectures based on Transformers. Each model offers specific benefits and drawbacks concerning design structure, training demands, and range of applications. This paper provides a detailed comparison …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 1, 2025 · pp. 16–22 Read article
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Mechanical and Thermal Performance of PETG Composites Reinforced with Short Carbon Fibers via Fused Filament Fabrication
Abstract: The study investigates the fabrication and characterization of polyethylene terephthalate glycol (PETG) composites reinforced with short carbon fibers (CF) using the fused filament fabrication (FFF) technique. Composite filaments with varying CF weight fractions (0, 5, 10, 15, and 20 wt%) were produced and evaluated for their mechanical, thermal, and morphological performance. The influence of CF reinforcement on tensile, flexural, and impact behavior was systematically examined, alongside thermal stability metrics including …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1219–1238 Read article
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Nanotechnology In Herbal Medicine
Abstract: Herbal medicine has been widely used for centuries as a natural and holistic approach to health care. However, many herbal compounds face challenges such as low solubility, low bioavailability, instability, and the lack of targeted delivery, which affect their efficacy. The integration of nanotechnology into herbal medicine has emerged as a promising strategy to overcome these challenges and enhance the pharmacological potential of plant-derived compounds. Nanocarriers such as liposomes, solid …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 50–69 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Tailoring The Electrochemical Interface of Graphene–Gd₂O₃ Nanocomposites for Advanced Energy Storage
Abstract: Graphene–Gd₂O₃ nanocomposites were synthesized by incorporating varying concentrations of reduced graphene oxide (rGO) into Gd₂O₃ using a straightforward room-temperature solution method. The composites were analyzed using various distinct characterization techniques, including X-ray diffraction (XRD), Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). Electrochemical measurements, particularly cyclic voltammetry (CV), demonstrated that the incorporation of graphene significantly enhanced the electrochemical performance …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 369–388 Read article
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Recent Trends in Heavy Metal Pollution of Groundwater: A Review
Abstract: Heavy metal pollution in groundwater has emerged as a major environmental and public health concern worldwide due to its persistence, toxicity, and potential for bioaccumulation. Rapid industrialisation, urban expansion, intensive agriculture, mining activities, and improper waste disposal have significantly increased the release of heavy metals into subsurface environments. Groundwater, being a primary source of drinking water in many regions, is particularly vulnerable to contamination, posing serious risks to human health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 4, Issue 1, 2026 · pp. 14–24 Read article
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Material-Level Degradation of Magnetorheological Fluids Under Long-Term Cyclic Shear
Abstract: The long-term functional stability of magnetorheological fluids (MRF) remains a key limitation for their reliable use in adaptive systems and continuously operated magnetorheological devices. In this study, the intrinsic evolution of rheological properties in a commercial MRF (MRC-C1L) is systematically examined under prolonged cyclic loading, with the aim of isolating material-level degradation mechanisms independent of device-related effects. The fluid was subjected to 120,000 low-strain oscillatory shear cycles under a constant …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 101–112 Read article
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Unfolding the Awareness for Women and Children in Vidarbha Region
Abstract: The concept of “Roots and Wings” as a pathway to empower women and children in Vidarbha region, focusing on the need for both a strong foundation and the freedom to thrive. “Roots” symbolize support systems like education, cultural identity, and community care, while “wings” represent opportunities for growth, self-expression, and independence. Women in Vidarbha often face deep-rooted challenges, including gender inequality, domestic violence, menstrual health, abuse and a lack of …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 · pp. 39–45 Read article