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552 articles for “HIV-1 Integrase” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article
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Exploring Moth Diversity in the Ecosystem of Mangalore University Campus, Karnataka
Abstract: The moth is one of the genera of insects of the order Lepidoptera, where butterflies share the same genus. They have nocturnal habits and a high attraction to light. Moths have various sizes, shapes, and colors, with many having duller colors. A study was conducted on the diversity of moth species in Mangalore University campus, Mangalore, Karnataka, for eight months (August 2006 to March 2007). We recorded 39 moths belonging …
Published in International Journal of Insects · Vol. 1, Issue 1, 2024 · pp. 22–29 Read article
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Synthesis, Characterization, and Reactivity of Bivalent Tin(II) with 4-Tert-butylphenol
Abstract: Bivalent tin(II)-4-tert. butylphenoxide of composition Sn(OC6H4X-4)2(I), where X = But, has been synthesized by the reaction of stannous chloride (SnCl2) with bimolar amounts of 4-tert. butyl phenol (HOC6H4But-4) in the presence of the base, diethyl amine, in tetrahydrofuran (THF) solvent. The resulting complex was characterized by elemental analysis, molecular weight determination, molar conductance measurement, IR, and 1H NMR spectral studies. The reactivity of the newly synthesized complex (I) with HgCl2 …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 14–19 Read article
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Geochemometric Assessment of Primordial Radionuclides and Trace Elements in Coastal Sediments: Environmental and Radiological Implications for South India
Abstract: This study focuses on environmental radioactivity and trace element contamination in coastal sediments along the southern region of the Indian subcontinent, from the Palar River to Pulicat Lake. Utilizing gamma-ray spectroscopy with a NaI (Tl) detector, along with atomic absorption spectroscopy, the research examines the spatial distribution and activity concentrations of primordial radionuclides—namely, 238U, 232Th, and 40K—as well as trace elements such as Ni, Pb, Mn, Zn, Cu, Co, Fe, …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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Harnessing the Potential of Insectivorous Birds in Managing the Rice Leaf Folder, Cnaphalocrocis Medinalis in Paddy Ecosystems of Kerala
Abstract: This study evaluates the effectiveness of various treatments for managing leaf folder pests in rice crops during the maximum tillering stage, focusing on the role of insectivorous birds. The treatments included bird perches (T1), nylon nets (T2), Bt spray (T3), a combination of bird perch and Bt spray (T4), flubendiamide spray (T5), and a control group (T6). Results indicated significant differences in pest densities. T2 showed the highest mean density …
Published in International Journal of Insects · Vol. 1, Issue 2, 2024 · pp. 6–9 Read article
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A Study of Metabolic Responses of R.Q, VO₂, and VCO₂ in Two Different Swimming Strokes
Abstract: This study investigates the metabolic responses, including Respiratory Quotient (R.Q), oxygen intake (VO₂), and carbon dioxide output (VCO₂), in freestyle and butterfly stroke swimmers. Understanding these responses is crucial for optimizing training and improving competitive performance. The study employed a comparative cross-sectional design involving 30 university-level swimmers (15 freestyle and 15 butterfly) who completed treadmill tests. Measurements of VO₂ and VCO₂ were taken using an S147 Rapid Response O₂/CO₂ Analyzer, …
Published in Recent Trends in Sports · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Eyes for Machines: A Computer Vision Approach to Enhance Robotic Arm Dexterity and Autonomy
Abstract: By combining sophisticated robotics and visual awareness, computer vision operated robotic arms have revolutionized technology. These devices are having a profound effect on several industries, from manufacturing processes to healthcare. Computer vision–controlled robotic arms are altering the game with their ability to see, comprehend, and interact with their surroundings. In this study we have tried to develop and implement software and hardware to improve the freedom of movement in a …
Published in International Journal of Advanced Control and System Engineering · Vol. 2, Issue 2, 2024 · pp. 28–33 Read article
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Analysis of Thermal Performance Improvement of Engine Fins by Varying the Materials and Profiles Used at High Temperatures
Abstract: In this thesis, we will design fins using various profiles and materials to identify the optimal combination for a 100cc engine. We will also test different materials for fins to evaluate the engine's heat efficiency. Our study will involve a comparison between the optimized fins and the original aluminum fins currently used. To ensure the optimal performance of the 100cc engine, we will utilize advanced analytical software to thoroughly analyze …
Published in International Journal of Energy and Thermal Applications · Vol. 2, Issue 1, 2024 Read article
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Development of Automobile Scaled Model from CAD (Blender) Using FDM 3D Printing
Abstract: Additive manufacturing (AM), also known as 3D printing, has emerged as a disruptive technology with the potential to transform automotive manufacturing. This paper reviews the applications of AM across the automotive product development lifecycle. The paper examines case studies demonstrating the use of AM for developing computer-aided design (CAD) models from concept sketches. Overall, AM brings several benefits such as design flexibility, faster time-to-market, and distributed production. However, there are …
Published in International Journal of Advanced Control and System Engineering · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Impact of Topical Pure Honey Application on Radiation-induced Oral Mucositis in Patients Receiving Radiation Therapy
Abstract: This quasi-experimental study assessed the effects of pure honey on radiation-induced oral mucositis in patients with head and neck cancer undergoing radiation therapy in Kottayam. The primary objectives were to evaluate the severity of oral mucositis in both experimental and control groups, determine the effectiveness of honey in alleviating symptoms, and examine the relationship between mucositis severity and selected demographic variables. Utilizing Bertalanffy’s General System Model as a conceptual framework, …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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IP Transcendence: Unifying IPv6 Over IPv4 Network
Abstract: Dynamic routing also called adaptive routing like traditional glass optical fiber, POF uses a polymethyl methacrylate (PMMA) core with a fluorinated polymer cladding, resulting in a larger core diameter that simplifies alignment and splicing. POF's adaptability is one of its main benefits. Because of their fragility and stiffness, ordinary glass fibers would not be practicable in certain situations where POF can be put. POF is a great option for intricate …
Published in International Journal of Electrical Power and Machine Systems · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
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Evaluate the Impact of a Structured Educational Program on Postnatal Mothers’ Understanding of Kangaroo Mother Care in a Tertiary Care Hospital
Abstract: Background and Aims:Kangaroo mother care (KMC) is an innovative method for caring for low-birth-weight infants. The main goal of this study is to evaluate the effectiveness of a structured teaching program in enhancing knowledge about KMC among postnatal mothers admitted at a tertiary care hospital. Material and Methods: Pre-experimental one-group pre-test and post-test designs were used and selected 80 postnatal mothers who met the inclusion criteria the experimental group received …
Published in International Journal of Midwifery Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article
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Comparative Efficacy of Hybrid Capture 2 and Real-Time PCR in Detecting High-Risk HPV Genotypes for Cervical Cancer Screening
Abstract: Human papillomavirus (HPV) infection is a leading cause of cervical cancer, making early detection critical for effective prevention and treatment. Among the diagnostic methods available, Hybrid Capture 2 (HC2) and Real-Time Polymerase Chain Reaction (PCR) are widely used for detecting high-risk HPV genotypes, particularly HPV 16 and 18, which account for the majority of cervical cancer cases. This review aims to compare the efficacy of HC2 and Real-Time PCR in …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 13–17 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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An Investigation to Evaluate the Awareness of Obesity and Its Long-term Consequences Among Adolescents from a Chosen Higher Secondary School in Bagalkot
Abstract: Using descriptive research methodology and a descriptive survey strategy, teenagers from a selected higher secondary school in Bagalkot were asked to rank their awareness of obesity and its long-term implications. To satisfy the objectives of the study and assess teenagers’ knowledge of obesity in light of the nature of the issue, a systematic, self-administered knowledge questionnaire was created. Interaction with guides and experts in the nursing and medical domains verified …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 33–37 Read article
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New Insight into the Composition and Structure of Sizing Agent from NMR Spectroscopy
Abstract: Sized carbon fibers (CFs) are of commercial significance as they form the main load-bearing component in advanced materials, namely, carbon fiber-reinforced plastics (CFRPs). Much of the knowledge of sizing composition and the process of sizing is a subject of intellectual property rights owing to its commercial relevance. In this original research article, deeper insights into the structure and composition of the sizing agent used for the surface modification of commercial …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 06–23 Read article
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History and Historiography of Origin and Development of Maiduguri Borno State, Nigeria
Abstract: This study discussed the history of Maiduguri as pertain to its growth, economic, educational development and its administrative structure. Materials for the work were mainly retrieved from the library where extant work attributed to some to some scholarly sources were used. The internet was also a useful source as some scholarly papers placed there helped a great deal. In essence, this library research that relied heavily on previous research on …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 5–13 Read article
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Elemental Mobility and Provenance in Sediments: A Geochemical Study of Deccan Basalts, Bay of Bengal, and Northern China
Abstract: Twenty-eight sediment samples from seventeen rivers, including the Krishna headwaters and the west-flowing Western Ghat rivers, draining the Deccan Trap basalts, were analyzed for major elements (Na, Ca, Mg, K, Al, Ti, Fe) and trace elements (Sr, Ba, Mn, P, V, Cr, Ni, Cu, and Zn). The mobility of these elements, especially Na, Ca, Mg, and Sr, was assessed by comparing their abundances in sediments and dissolved phases. Approximately 60% …
Published in International Journal of Minerals · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Effect of Carbon Nanotube on Mechanical Properties of Jute Fibre Reinforced Polyester Composite
Abstract: The current study studies how carbon nanotubes affect the mechanical characteristics of polyester composites reinforced with jute fiber, both treated and unprocessed. Alkali was used to cure jute textiles. Composites with treated and untreated jute fibre with 5%, 10% and 15% jute fibre loading with and without carbon nanotube were prepared using hand lay-up process. Carbon nanotubes varied from 0.2%, 0.4% and 0.6%. Tensile, flexural, and strength of impact all …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 1–9 Read article