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338 articles for “Cancer Cell”
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Detrimental Effect of Mobile Phone Radiation on Living Organisms: An Update Review
Abstract: Mobile phone has raised the risk of the tissue-level damage for all living organisms not only for human and animals but plants as well. Numerous studies have documented various biological effects of EMR including changes in cell proliferation, enzyme activity, gene expression, cell-membrane permeability and ion homeostasis as well as oxidative stress and heat-shock response. A modulated field at 900 MHz strongly inhibited the growth of and, to some extent, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 2, 2013 · pp. 34–42 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 42–49 Read article
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Everlasting Life Achieved Through Technology in AI
Abstract: The concept of immortality Life is a philosophical idea that states life is limitless and does not stop with death, it exists infinitely. In our Sanskrit scriptures and Santana dharma teach us that there is a life of beginning and an end, which are referred to as birth and death but our souls do not perish, instead, they switch bodies. In this scenario, our memories have evaporated to protect our …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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A Comprehensive Study on Protein-Protein Interaction in Drug Development: Future Prospective and Challenges
Abstract: Protein-protein interactions (PPIs) play important roles in various cellular processes and have become a major area in drug development. Most of the studies which are related to Protein-protein interactions (PPIs) are correlated with different types of diseases including infectious diseases, Cancer and Neurodegenerative disorders. Therefore, targeting PPIs constitutes a therapeutic avenue for disease and an essential strategy for new drug development. In the last 10 years, PPI has been an …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 2, 2023 · pp. 25–31 Read article
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Polymer Based Optoelectronics in Clinical Application Treated with Sodium Fluoride and Aqueous Dimethyl Sulfoxide Solutions
Abstract: In polymer science, dimethyl sulfoxide (DMSO) and sodium fluoride (NaF) are frequently combined to dissolve, modify, or treat particular polymers, most notably in the processing of cellulose and the creation of polyvinylidene fluoride (PVDF) membranes. The viscosities, ultrasonic velocities, and sodium fluoride densities of aqueous solutions of dimethyl sulfoxide (DMSO) have been measured at T=303.15, 308.15, 313.15, and 318.15 K. Fluorides (such as NaF or TBAF) help break inter-chain hydrogen …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 20–29 Read article
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Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
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Role and impact of Dietary Antioxidants on Aging and Lifespan: A Review
Abstract: The effect of an antioxidant-rich diet on aging and lifespan has attracted significant scientific attention, primarily through the lens of the free radical theory of aging (FRTA). This theory suggests that oxidative stress caused by an accumulation of reactive oxygen species (ROS), accelerates aging and contributes to cellular damage. The accumulation of free radicals and the oxidative damage that is induced significantly contribute to the aging process. This imbalance plays …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 72–82 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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The Multifaceted Vitamin B6: Metabolism, Cardiovascular Health, Cognition, and Cancer
Abstract: Vitamin B6 is hydrophilic and plays a crucial role in various metabolic processes. It acts as a cofactor in different enzymatic reactions. Vitamin B6 exists in various forms, including pyridoxal 5'-phosphate (PLP), the most active form. Vitamin B6 is essential for amino acid metabolism, such as PLP is essential for transamination, the process of transferring amino groups between amino acids. This is vital for synthesizing non-essential amino acids and breaking …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 2, 2025 · pp. 33–39 Read article
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Role of Nitric Oxide Synthase in Platelets of Breast Carcinoma
Abstract: Breast cancer is the leading problem of the world. Free radicals have unpaired electron which can be neutralised by human body for maintaining health, these free radicals are toxic, highly unstable and very reactive. Antioxidants and free radical scavengers protect cells from toxic effects in order to maintain redox state of the cell. Nitric oxide is one of the important free radicals synthesized from nitric oxide synthase. It has been …
Published in Research and Reviews: A Journal of Health Professions · Vol. 9, Issue 1, 2019 · pp. 36–39 Read article
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Intelligent Brain Tumor Diagnosis with AI-Based Classification* * Harnessing Deep and Machine Learning for Tumor Identification
Abstract: Brain tumors have become a leading cause of cancer- related deaths, posing significant health risks to many patients. This urgent medical challenge calls for rapid, automated, and reliable techniques to detect brain tumors accurately. Timely and precise tumor identification is crucial for devising effective medical plans that have the potential to save lives and improve patient outcomes. By leveraging advanced image processing methods, healthcare professionals can enhance their diagnostic capabilities …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 · pp. 51–58 Read article
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Immunohistochemical Detection of c-Myc in Lungs of Sheep with Ovine Pulmonary Adenocarcinoma
Abstract: vine pulmonary adenocarcinoma, a naturally occurring lung cancer of sheep was diagnosed in seventeen cases at slaughter houses. Lung tumor tissues and associated lymph nodes were collected for histopathological and immunohistochemical studies. Histologically, the lung sections from OPA cases revealed areas of non encapsulated proliferation of alveolar epithelial cells in papillary or acinar pattern. Polyploid ingrowths were also noticed into the bronchioles. On immunostaining of lung sections, JSRV-MA protein was …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 2, 2015 · pp. 13–17 Read article
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Arsenic as a Cause of Cancer
Abstract: Inorganic Arsenic (iAs) is a pervasive and ubiquitous environmental toxin that has created world-wide human health problems. Populations exposed to high concentrations of arsenic-contaminated drinking water suffer serious health consequences ranging from acute toxicities to development of malignancies, including alarming cancer incidence and death rates. Epidemiologic studies have shown a relationship between chronic arsenic exposure and disease of the skin, lung, urinary bladder, and conceivably liver, kidney, and prostate in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 3, 2016 · pp. 8–21 Read article
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Effect of Sodium Fluoride and Cellulose Gum Toothpaste over Regular SLA Toothpaste in Reducing Xerostomia-A Retrospective Cohort Study
Abstract: Our aim is to study the effect of mildly flavoured sodium fluoride 0.2% and cellulose gum on patient suffering from chronic xerostomia in comparison to effect of general sodium Laurel sulphate containing toothpaste on same condition patient. A controlled study population was used for the investigation. The baseline for this study is to estimate the risk of developing xerostomia or worsening of the condition in patient already suffering from xerostomia …
Published in Research and Reviews: A Journal of Dentistry · Vol. 13, Issue 2, 2022 · pp. 22–24 Read article
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Review on Histological Effect of Lead on Liver and Kidney
Abstract: Our environment can be polluted by environmental toxins which are chemicals and other materials produced largely from industry and its products. There are large numbers of environmental toxicants which are potentially harmful to health. These large numbers of environmental toxicants can be divided into three major categories (heavy metals, air pollutants, and pesticides) and they are commonly studied environmental toxicants. Environmental toxins can be entered into the body by various …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 8–29 Read article
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Integrated Approach of Unani Medicine in Geriatric Care
Abstract: Aging is a process of physical, psychological and social changes in multidimensional aspects. The percentage of elderly, in the world population is expected to increase rapidly from 9.5% in 1995 to 20.7% in 2050 and 30.5% in 2150. In India, the population of older people has risen from 4.9% in 1901 to 5.5% in 1951, 6.5% in 1991, 7.7% in 2001, and 8.3% in 2011 and will be 12% in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2015 · pp. 4–9 Read article
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Advances in Lung Cancer Detection and Diagnosis: An Integrative Approach Using Computational Chemistry, Statistics, Bioinformatics, Artificial Intelligence, and Machine Learning
Abstract: Lung cancer is still one of the most common and lethal cancers globally, accounting for more than a million deaths each year. Prompt detection is important, and imaging techniques like chest X-rays, MRIs, PETs, CTs, and molecular imaging have become important tools. But still, even though all these techniques do not provide an accurate classification of the lesion, they have led to the development of computer-based high-resolution image analysis. Computer …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 2, 2026 Read article
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An Overview of Gene Therapy
Abstract: Gene therapy is a revolutionary technique in medical science that seeks to cure or stop illnesses by means of introducing, altering, or quieting genes inside a patient's cells. Advancements in molecular biology, genetics, and biotechnology have propelled this field forward markedly changed over the last few decades. The underlying idea of gene therapy is to introduce genetic material into target cells via viral or non-viral vectors to rectify faulty genes, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 89–105 Read article