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394 articles for “therapeutic drug”
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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The Therapeutic and Biotechnological Potential of Pogostemon benghalensis – A Comprehensive Review
Abstract: Pogostemon benghalensis is a fragrant perennial shrub belonging to the family Lamiaceae, widely distributed across tropical and subtropical regions of Asia. It has been extensively utilized in traditional and ethnomedicinal systems for the treatment of wounds, skin infections, fever, digestive disorders, inflammation, and respiratory ailments. The plant is also valued for its antiseptic, aphrodisiac, insect-repellent, and veterinary medicinal properties. Its leaves, roots, and essential oil are incorporated into herbal formulations, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 55–63 Read article
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Effect of Virechana Karma, Ketaki-Rasonadi Brimhana-Sneha and Amritadi Ghanavati in Asthikshaya w.s.r. Osteoporosis
Abstract: It is estimated that worldwide, osteoporosis causes more than 8.9 million fractures annually. Long-term use of modern medication of osteoporosis are generally associated with adverse effects like deep vein thrombosis, pulmonary embolism, endometrial cancer, ulcers of esophagus, upper GI irritation, irregular heartbeat and thromboembolic disease. As such, no direct reference of osteoporosis is available in Ayurveda but similar condition is described under different diseases like Asthikshaya, Asthimajjagata Vata. The proper …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2016 · pp. 61–69 Read article
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Therapeutic Effect of Asthishrunkhala (Cissus quadrangularis) in Fracture Healing and Other Disease Conditions
Abstract: Skeletal health is important to maintain quality life, as it is known that qualitative bone helps preventing untoward bone fractures because of a good level of bone marrow density (BMD), but due to several factors, like the ageing process the skeletal strength decreases from natural lowering of BMD, since ancient ages plants have served human beings as a natural source of treatment and therapies, among them many medicinal herbs have …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 3, 2017 · pp. 11–15 Read article
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Medicinal Plants with Potent Antidiabetic and Wound Healing Activity: A Review
Abstract: Wound healing is impaired in diabetic patient with infection or hyperglycemia, and because of the increasing incidence of diabetes worldwide wound healing occupies an important and developing fields of research in modern biomedical sciences. As such process of wound healing is highly complicated and becomes more complex when associated with a condition like diabetes which itself is a substantial socioeconomic and quite serious life burden. As a consequence of its …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 1, 2015 · pp. 21–36 Read article
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Pharmacological Management of Behavior in Children
Abstract: This research work aims to review various drugs used for the management of behavior in children. Pharmacological management describes the use of various drugs to manage the behavior of pediatric patients undergoing dental procedures. Several types of drugs and routes of administration (e.g. oral, recta, intramuscular, intravenous etc.) have been tested to achieve this aim. The use of sedative drugs along with local anesthetics has shown to reduce anxiety and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 11, Issue 1, 2020 · pp. 8–17 Read article
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Development of Antioxidant Based Therapeutics in Unani System of Medicine
Abstract: During the last decades, several studies have examined the potential role of oxidative stress in the development of various diseases like cancer, Parkinson's disease, Alzheimer's disease, atherosclerosis, myocardial infarction, chronic fatigue syndrome etc. Oxidative stress can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Unani system of medicine has a wealth of antioxidants that can …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 5, Issue 3, 2018 · pp. 1–4 Read article
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Evaluation of Polyethylene Glycol (PEG)-Based Polymers for Improving Solubility and Bioavailability of Poorly Soluble Drugs
Abstract: A significant barrier to optimizing oral bioavailability is the inadequate water solubility of numerous pharmaceutical compounds. This study examined whether polymer systems utilizing polyethylene glycol (PEG) may enhance the solubility and bioavailability of a poorly soluble model drug. Multiple PEG polymers with molecular weights between 2,000 and 10,000 Da were utilized to produce PEGylated preparations. The formulations were subsequently evaluated for dissolution efficacy, medication loading capacity, particle size, and solubility …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 489–499 Read article
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Unani Management of Kasrate Tams (Menorrhagia): A Literary Review
Abstract: Menstrual disorders have drawn much attention of the gynaecologists and physicians at present and in the ancient times more than any other health problems of the females. Among all gynaecological problems, “Menorrhagia (Kasrate Tams/Ifrate Tams)” is one of the most common complaints in menstruating females. Approximately it affects 10 to 15% of the adult female population. It is a problem that affects physical, emotional, and social activities and quality of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 8, Issue 1, 2021 · pp. 28–34 Read article
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Phosphorescence of Carbon Nanodots – The Phenomena and the Applications
Abstract: Photoluminescence has emerged as a fundamental phenomenon in modern biomedical science, enabling advanced diagnostic, therapeutic, and theranostic applications through light–matter interactions at the nanoscale. The ability of photoluminescent materials to absorb electromagnetic radiation and emit light at distinct wavelengths has been widely exploited in bioimaging, biosensing, drug delivery tracking, and photodynamic therapy. Among various photoluminescent nanomaterials, carbon nanodots have attracted significant attention due to their strong emission intensity, tunable fluorescence, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 01–05 Read article
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Psychoactive and Physiological Homogeneity of Cannabis: A Literature Review: Actions of the Medical Plant that Takes Care of Itself
Abstract: Naturally occurring plants like Cannabis and the biologically ubiquitous alkaloids (e.g., morphine, quinine, and atropine) are composed of mostly physiological and psychoactive compounds. Extracts of the Cannabis plant are not alkaloid substances nor are they not related chemically to alkaloids, having no component nitrogen in their structures. Three species of Cannabis (marijuana) are recognized in scientific classifications: Cannabis sativa, Cannabis indicus and Cannabis ruderalis. Cannabis sativa is the species that …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 1–4 Read article
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Polysaccharide-Based Hydrogels for Sustained Drug Release in Pharmacology
Abstract: Polysaccharide-based hydrogels have showed great potential in medicine as materials for long-lasting, under control medication delivery systems. Natural polysaccharides include chitosan; alginate, agarose, and cellulose form these hydrogels. Among its many advantages are biocompatibility, biodegradability, and customising ability for various drug release rates. Reacting to pH, temperature, and ionic strength changes in the surroundings, polysaccharide-based hydrogels may swell. For usage requiring the release of therapeutic substances over an extended period …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 300–312 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Polymer Chemistry and Its Applications in Pharmaceutical Composite Formulations
Abstract: Polymer chemistry plays a critical role in pharmaceutical formulations, particularly in enhancing drug stability, bioavailability, and controlled release. Polymers are widely utilized in drug delivery systems. Polymers are widely used in pharmaceutical sciences for drug delivery, controlled release, and stability enhancement. This paper explores the role of polymers in the extraction and formulation of glycyrrhetinic acid from Glycyrrhiza glabra, a bioactive compound. Various polymer-based extraction and purification techniques are discussed, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 216–221 Read article
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Digital Therapeutics for Management of Chronic Diseases
Abstract: Digital therapeutics (DTx) mark a major advancement in modern medicine, using advanced software technologies to deliver clinically validated treatments for various physical and mental health conditions. Unlike general wellness apps that focus on fitness or lifestyle tracking, DTx are evidence-based medical interventions developed through rigorous clinical research to ensure safety, efficacy, and measurable outcomes. Delivered via digital platforms such as smartphones, tablets, or specialized medical devices, DTx aim to prevent, …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Antibacterial Activity of Pongamia pinnata Leaf and Callus Extracts against Microorganisms Causing Periodontal Diseases
Abstract: Some specific microorganisms have been identified as etiologic agents of periodontitis. The main goal of treatment is to control the spread of infection. Depending on the extent of the gum disease, treatment varies. Therapeutic antibiotic along with surgery are the most opted form of treatment. But, due to high costs of antibiotics, the disastrous side effects and emergence of multi drug resistant strains of these pathogenic bacteria, a safe alternative …
Published in Research and Reviews: A Journal of Dentistry · Vol. 3, Issue 2, 2012 · pp. 1–7 Read article
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Therapeutic Importance of Sumbul-ut-Teeb (Nardostachys jatamansi DC)
Abstract: Background: Sumbul-ut-teeb is an important medicinal plant and has been extensively used in the Indian system of medicine. Sumbul-ut-teeb is an erect, small, perennial, rhizomatous herb. There is a plethora of experimental and clinical evidence showing its medicinal activity. Varieties: There are three varieties of Sumbul-ut-teeb that are mentioned in the Unani System of Medicine as a drug that is, Sumbul Hindi, Sumbul Romi, and Sumbul Jabli (pahadi). Sumbul Hindi …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 1, 2023 · pp. 10–17 Read article
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Fungal-derived Nutraceuticals & Bioactive Compounds with Physiotherapeutic and Health- promoting Properties: A Comprehensive Review
Abstract: Fungal-derived nutraceuticals represent a rapidly expanding field in biomedical research, offering a rich source of bioactive compounds with diverse therapeutic applications. This comprehensive review examines the physiotherapeutic and health-promoting properties of fungal metabolites, including polysaccharides, terpenes, proteins, peptides, alkaloids, fatty acids, vitamins, and minerals. Fungi produce over 9,000 bioactive compounds from approximately 22,500 microbial metabolites, with less than 5% of the fungal kingdom explored [1] . The major bioactive constituents …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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The Impact of Extraction Conditions on the Trend of the Type of Red Onion and the Characteristics of Oil Harvest for the Use of Constraints
Abstract: The therapeutic potential of plant-derived medicinal products, including essential oils, has not yet been fully exploited. Many medicinal plants have been studied to provide the biologically active compounds on which most modern drugs are based. However, much more remains to be learned about their precise pharmacology. This is particularly important for essential oils which have such a concentrated but complex composition. This is the reason for the interest they generate …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 70–76 Read article