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296 articles for “Targets”
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Activated Carbon Materials as Ideal Adsorbents for the Desulfurization of Fossil Fuels
Abstract: Removal of organosulfur compounds from diesel is of interest from scientific, social, economic, and environmental viewpoints. Production of clean fuel remains a primary goal of the petroleum refining industry. The reduction of sulfur content below stringent ppm levels in diesel fuels becomesincreasingly challenging due to the presence of sterically hindered sulfur compounds, such as 4,6- dialkyldibenzothiophenes, which are resistant to removal over conventional supported mixed sulfide hydrodesulfurization catalysts. Consequently, alternative …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 28–34 Read article
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Cosmetic Topical Formulations: Design Strategies, Skin Interaction Mechanisms, Clinical–Cosmetic Applications, and Emerging Trends
Abstract: Cosmetic topical products are central to modern skin care, as they deliver active ingredients directly to the skin surface and upper layers to improve appearance, texture, and function. By acting locally on the epidermis and adnexal structures, these preparations help manage dryness, photoaging, pigmentation, acne, and sensitive-skin conditions while minimizing systemic exposure. A wide range of dosage forms—creams, lotions, gels, ointments, serums, sprays, and transdermal-inspired cosmetic patches—are engineered to modulate …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 39–47 Read article
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Molecular Docking of Abroma augusta Phytocompounds Against Estrogen Receptor Alpha (Er-Α) for the Treatment of Menstrual Disorders
Abstract: Menstrual disorders, including dysmenorrhea (painful menstruation), amenorrhea (absence of menstruation), and irregular menstrual cycles, significantly impact women’s reproductive health and overall well-being. These conditions often arise from hormonal imbalances, inflammation, and uterine dysfunction, necessitating effective therapeutic interventions. Current treatments, such as hormonal therapies (oral contraceptives, progestin-only pills), NSAIDs, and surgical procedures (endometrial ablation, hysterectomy), provide relief but often target symptoms rather than addressing the underlying causes. Consequently, there is a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 · pp. 1–12 Read article
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Fungi in the Global Bioeconomy: Harnessing the R Potential Across Agriculture, Medicine, Industry, and Environmental Sustainability
Abstract: One of the most diverse and functionally versatile groups of living organisms, fungi has played a significant role in maintaining ecological balance, human well-being, agricultural production, and industrial processes. Despite their vast potential, the use of fungi systems in solving some of the most serious challenges facing the world today, such as climate change, food security, and AMR, is still in its infancy. New developments in genomics, biotechnology, and systems …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 20–27 Read article
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A Study to Assess the Knowledge Regarding Pradhan Mantri Jan Arogya Yojana (PM-JAY) Among the General Public in a Tertiary Care Teaching Hospital, Kuppam
Abstract: Background: Ayushman Bharat, the flagship scheme of the Government of India, was launched to achieve Universal Health Coverage (UHC) as per the National Health Policy 2017. It aims to address healthcare needs comprehensively by transitioning from fragmented approaches toward a holistic system. Pradhan Mantri Jan Arogya Yojana (PM-JAY) is a pivotal component of this scheme, striving to achieve UHC by providing comprehensive healthcare services to underprivileged families. Assessing public awareness …
Published in International Journal of Community Health Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 1–6 Read article
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Challenges And Constraints Affecting Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: This study examined the challenges and constraints affecting female-owned rural farm businesses in Plateau State, Nigeria. No prior study had conducted a comprehensive, quantitative, state-wide investigation covering all 17 local government areas (LGAs) of the state, and this study addressed that gap. The objectives were to identify the challenges faced by female-owned rural farm businesses, assess their relationship with business performance, and determine how strongly these challenges predicted performance outcomes. …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 1–13 Read article
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Nature’s Pharmacy: Plant-Based Antifungal Agents and Their Therapeutic Potential
Abstract: Antifungal resistance has increased dramatically over the last 10 years, causing serious problems for healthcare because of higher morbidity and death. The urgent need for new treatments is highlighted by the scarcity of effective antifungal medications, their toxicity, and the rise of resistant strains. Since many plants have bioactive secondary metabolites with strong antifungal qualities, including alkaloids, flavonoids, terpenoids, phenolics, and saponins, ethnobotanical sources offer a viable path. Plants with …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 1–7 Read article
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Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, shifting replication domains and reshaping mutational patterns critical for cancer evolution (1,5). DNA replication timing (RT) domains serve as dynamic epigenetic organizers, partitioning the genome into early- and late-replicating regions that correlate with chromatin states, gene …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Predictive Analytics and Adaptive Learning: A Machine Learning Framework for Reducing Learning Gaps
Abstract: Most contemporary digital learning environments encounter persistent challenges when it comes to accurately identifying students who are at-risk of academic underperformance. These challenges often arise due to limited visibility in learners’ engagement levels and gaps in conceptual understanding, particularly during the early stages of a course. To address this issue, the present study proposes an early prediction framework that leverages comprehensive student-related data through the application of machine learning techniques. …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 4, Issue 1, 2026 · pp. 16–21 Read article
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Women Empowerment: The Essential Role of Education for Women in India
Abstract: Education has long been acknowledged as one of the most powerful instruments of social transformation, and in the Indian context, it holds unique significance for women’s empowerment. The empowerment of women is central to reducing gender inequality, dismantling patriarchal norms, and achieving inclusive growth. Women’s education does not merely provide literacy; it develops autonomy, fosters confidence, and equips women with the skills necessary for meaningful participation in social, political, and …
Published in International Journal of Trends in Humanities · Vol. 3, Issue 1, 2026 · pp. 20–24 Read article
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Investigation of Pollution Status in River No. 2, Freetown, Sierra Leone, Using Physicochemical and Bacterial Indicators
Abstract: This study assessed the physicochemical and bacteriological quality of surface water in the River No. 2 watershed, Sierra Leone, through monthly sampling from March–August 2024 at upstream, midstream, and downstream sites. Analyses included temperature, turbidity, pH, electrical conductivity, total dissolved solids, ammonia, fluoride, sulfite, nitrate, lead, arsenic, chromium, and microbial indicators (Escherichia coli, fecal and non-fecal coliforms). Most physicochemical parameters met WHO drinking-water guidelines. pH (7.0–7.3), TDS (7–17 mg/L), turbidity …
Published in International Journal of Pollution: Prevention & Control · Vol. 4, Issue 1, 2026 · pp. 11–27 Read article
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Labeling transparency and heavy metal contamination in commercial protein powders: A case study
Abstract: With the recent surge in market demand, health supplements particularly protein powders, have become increasingly vulnerable to quality deterioration, adulteration, and unethical marketing practices. Non-compliance with labeling regulations is on a rise. Moreover, research indicates that heavy metals absorbed from contaminated soil often accumulate in the protein fractions of crops, thereby elevating the risk of heavy metal contamination in protein powders. These issues highlight the urgent need to systematically assess …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 Read article
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Predictive Learning Powered by AI and Sophisticated Student Engagement Techniques
Abstract: The contemporary landscape of education has witnessed a paradigm shift in integrating advanced technologies that have revolutionized the learning experience. Innovative methodologies have emerged to address longstanding challenges, such as enhancing student engagement, accurately predicting academic performance, and personalizing the learning journey. However, despite the numerous benefits that technology brings to education, there remains a crucial hurdle - sustaining student motivation and engagement. Traditional teaching methodologies often struggle to generate …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 127–140 Read article
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Association Between Smartphone Addiction and Functional Exercise Capacity in College Students
Abstract: Smartphone addiction has become increasingly prevalent among college students and is associated with various negative physical and psychological outcomes. Functional exercise capacity, a key indicator of physical fitness and health, may be adversely affected by excessive smartphone use due to sedentary behavior and reduced physical activity. This article examines the association between smartphone addiction and functional exercise capacity in college students by analysing behavioral, psychological, physiological, and methodological perspectives. Evidence …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 Read article
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Study of Electrically Conductive Polymer for Antistatic and Sensor Application
Abstract: Electrically conductive polymers (ECPs) are a unique category of smart materials that integrate the mechanical flexibility and ease of processing characteristic of conventional polymers with the electrical conductivity typically associated with metals or semiconductors. In recent years, they have attracted considerable interest due to their promising potential in advanced technological applications, especially in antistatic coatings and electronic sensing devices. The unique ability of these polymers to conduct electricity arises from …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 46–51 Read article