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1941 articles for “Methods” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Optimization Of Mechanical Properties Of 500/7 Grade Ductile Cast Iron (DCI) By Using SMAW: Applications In Reinforced Composites And Thermoplastics Through Taguchi & GRA
Abstract: Welding, a critical manufacturing process, is broadly engaged to join metals and thermoplastics using heat, pressure, or both. This study inspects the Shielded Metal Arc Welding (SMAW) method to optimize welding parameters and improve the mechanical properties of Ductile Cast Iron (DCI) grade 500/7, a material widely used in high-strength and thermal conductivity applications in aerospace and automotive sectors. Using an L9 OA (orthogonal array), experiments were conducted on nine …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 204–222 Read article
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Authentication of a Rapid RP-HPLC technique for Quantification of Remogliflozin and Metformin in Medicinal Formulations
Abstract: A new, precise, and stability-assessing advanced liquid chromatography (HPLC) technique for simultaneous quantification of Remogliflozin and Metformin in fixed dose pharmaceutical formulations was designed and verified. Optimization of the technique was carried out on flowing phase composed of ethanenitrile and buffer, under isocratic conditions, the resolution of peak being sharp with retention times of 3.24 min and 4.89 min for Remogliflozin and Metformin, respectively. Technology suitability was confirmed by the …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 70–77 Read article
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CdS-Based Photocatalytic Nanostructures: A Promising Material for Various Environmental Applications
Abstract: Modern technological and industrial progress has significantly increased the use of chemicals in product development, leading to greater contamination of water sources by conventional pollutants (such as organic dyes and heavy metals) and harmful microorganisms. Wastewater treatment processes now reveal “emerging pollutants,” including pharmaceuticals, endocrine disruptors, and agricultural chemicals. Certain emerging pollutants, though harmless in some cases, can pose serious risks to various organisms. To address this, researchers are exploring …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 33–53 Read article
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Parametric Optimization of Aluminum Alloy 6061 Using Wire-EDM for Automotive Applications: A Taguchi-Based Approach
Abstract: Machining hard materials with complex geometries presents numerous challenges, often requiring the use of non-traditional methods such as wire Electric Discharge Machining (EDM). However, wire EDM machines operate at slow speeds, and increasing the speed can negatively impact surface finish, making it a difficult task. The ongoing research investigates the machinability study of Aluminum Alloy 6061 using wire EDM, emphasizing the optimization of process parameters to enhance machining performance and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 293–302 Read article
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Energy Storage Properties of hy-BST3/PVDF Nanocomposite for Dielectric Capacitor Application
Abstract: In the present research work, we have synthesized the ferroelectric ceramic Ba0.7 Sr0.3TiO3 (BST3)/PVDF (Polyvinylidene difluoride). Polymer nanocomposites for energy storage applications, designed to synergistically combine the high dielectric permittivity of hydroxylated barium strontium titanate (hy-BST3) with the mechanical flexibility and electroactive properties of poly(vinylidene fluoride) (PVDF). Hydroxylated Barium Strontium Titanate (hy-BST3) has been synthesized using the sol-gel combustion method followed by surface hydroxylation using H2O2 to achieve nanoscale particles …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 908–918 Read article
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Performance Evaluation of Concrete with Binary and Ternary Blends of Fly Ash, Silica Fume, and Fiber Reinforcement
Abstract: This study evaluates the effect of ground granulated blast furnace slag (GGBS) as a partial replacement for cement on the mechanical properties of concrete, focusing on compressive and split tensile strength. Concrete mixes were prepared with GGBS replacement levels of 0%, 25%, and 50% and subjected to different curing methods, including water curing, steam curing, and conceal curing. These curing methods were selected to investigate their impact on hydration, strength …
Published in Journal of Construction Engineering, Technology & Management · Vol. 15, Issue 3, 2025 · pp. 40–45 Read article
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Stability-Indicating Rp-Hplc Development and Validation for the Estimation of Lercanidipine Hydrochloride Content in Tablet Dosage Form
Abstract: A sensitive, stability-revealing, and easy reverse-phase high-performance liquid chromatographic (RP-HPLC) technique was developed and rationalized to be in a position to determine Lercanidipine hydrochloride in ingested dosing preparations. It was separated by chromatography on a C 18 column using a mobile phase containing 10 mM potassium dihydrogen phosphate buffer and methanol (20:80, v/v; pH 4.0) at a flow rate of 1.0 mL/min and UV detected at 258 nm. The retention …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 17–26 Read article
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Optimization of Machining Parameters of EN-27 Material Using Wire Electric Discharge Machining (WEDM)
Abstract: The optimization of Wire Electrical Discharge Machining (WEDM) parameters for EN-27 alloy steel, a high-strength material widely utilized in mechanical and structural applications, is the subject of this study's methodical analysis. Due to its hardness and poor machinability by conventional methods, WEDM is preferred for achieving precise dimensional accuracy and surface integrity. The primary objective of this work is to enhance machining performance by identifying optimal process parameters influencing Material …
Published in Journal of Production Research & Management · Vol. 16, Issue 1, 2026 · pp. 32–36 Read article
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Enhancement of Flexural Strength in FDM-Printed Components through Taguchi-Based Process Parameter Optimization
Abstract: Additive manufacturing (AM), especially Fused Deposition Modeling (FDM), has emerged as a widely adopted and versatile method for producing three-dimensional components. The process involves the deposition of a thermoplastic filament in a semi-molten state, which solidifies in successive layers to form the final structure. While this method enables the production of complex geometries at relatively low cost, the printed parts often exhibit inferior surface quality and reduced mechanical performance compared …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 272–280 Read article
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Effectiveness of a Planned Teaching Programme on Primigravid Mothers' Awareness of Specific Natural Pain Relief Techniques Used During Labor in Particular Bangalore Hospital
Abstract: Background: Pain is an exciting sensation and is caused by the stimulus during labor. Always Pain plays a major role in labor in empowering the women, whereby they triumph by giving delivery to the newborn. Objectives: Assess the knowledge level about selected natural pain relief methods. Methodology: A quantitative research approach and the design used in this study was a pre-experimental research design. Sixty primigravid mothers were selected for the …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 9–16 Read article
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Numerical Investigation of Heat Transfer Enhancement in Micro-Channel Cooling Using Finite Element Analysis
Abstract: Due to the enormous heat fluxes emitted by modern electronic chips, there is a persistent need to enhance the efficiency of cooling systems. This study's focus is on optimizing heat transfer in micro-channel heat sinks that use liquid cooling. Geometric changes and the use of nano-fluids as coolants in place of water are performed to achieve this goal with little energy consumption. Numerical analysis of pipe micro-channel fluid flow and …
Published in International Journal of Energy and Thermal Applications · Vol. 1, Issue 1, 2023 · pp. 36–44 Read article
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Analyzing the Sheet Metal Extrusion Process Using Finite Element Analysis
Abstract: A wide range of sheet metal forming techniques has been developed to make it easier to produce intricate 3D objects. However, the knowledge still isn't sufficient. The sheet metal extrusion method was examined in this research as one of the common sheet-bulk metal manufacturing technologies. Consideration of the flow-stress curve's impact across a broad range of plastic strain and ductile damage played a pivotal role in constructing a realistic finite …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 1, Issue 1, 2023 · pp. 13–25 Read article
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Development of Anti IgG Polyclonal Antibody Against Canine IgG and Their Roles in Diagnostic Purposes
Abstract: IgG plays an important part in immunological studies and also in living bodies for providing secondary immune response which triggers as passive immunization against harmful pathogens in dogs. Purpose: The aim of this investigation is to separate, identify, and refine immunoglobulin G from canine serum. Methods: Ammonium sulphate precipitation was used to separate the dog's serum, which was then concentrated over night in a dialysis bag inside of a refrigerator. …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 01–06 Read article
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Zinc Oxide Nanoparticles from Murayya koenigii: Antibacterial Potential Review
Abstract: Nanoparticles (NPs) display unique characteristics in contrast to conventional physico-chemical synthesis methods, and they are utilized in various life science fields including surface coating, catalysis, food packaging, corrosion prevention, environmental cleanup, electronics, biomedical applications, and antimicrobial purposes. Metal NPs synthesized through green methods, particularly from plant origins, have garnered significant interest because of their inherent traits such as environmental friendliness, quick production, and cost efficiency. Over the past few years, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 54–67 Read article
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Determining the Characteristics of Concrete Composed of Different types of Aggregates
Abstract: This study investigates the influence of recycled aggregates on the compressive strength of concrete designed for medium workability. Various replacement proportions of recycled aggregates (0%, 50%, 60%, and 100%) were examined using conventional mix design methods, specifically focusing on 10 mm recycled aggregates' impact. The specimens comprised 100% recycled aggregate, with a combination of 60% 20 mm and 40% 10 mm sizes. Compressive strength analyses were conducted at 7 and …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 1, 2024 · pp. 1–5 Read article
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Agro- residue Pretreatment Tools and Techniques: A Detailed review
Abstract: This review examines the significance of biomass pre-treatment in facilitating efficient biofuel production from lignocellulosic materials. Different methods of pre-treatment, such as acid, alkaline, liquid hot water, ionic liquids, organosolv, ozonolysis, wet oxidation, steam explosion, ammonia fiber explosion (AFEX), carbon dioxide explosion, and biological pretreatment, are examined in terms of their underlying principles, benefits, and drawbacks. Acid pretreatment effectively hydrolyzes hemicellulose but suffers from equipment corrosion and high operational costs, …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 1, 2024 · pp. 22–31 Read article
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Integration of Taguchi and MCDM Techniques for the Optimization of Experimental Parameters in Electrical Discharge Machining: A Research
Abstract: Electric discharge machining (EDM) represents a non-conventional approach to machining, particularly beneficial for processing hard-to-machine materials or components with high length-to-diameter ratios or intricate shapes. Widely employed across various industries such as automotive, chemical, aerospace, biomedical, and tool and die, EDM offers a unique method for achieving precise shapes and dimensions. Unlike traditional machining methods where form is attained through the interaction of the tool and workpiece, EDM operates without …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 6–14 Read article
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Parametric optimization and validation of novel 3D scanning approach for sustainable manufacturing of patient-specific orthodontic retainers
Abstract: The purpose of the proposed study is to identify the ideal procedure parameters for 3D scanning a denture in order to produce customised orthodontic retainers that can be produced sustainably. However, pilot investigations rarely explore parameters like scanning angle, light intensity, or scanning distance. In order to lower acquisition error, the suggested study examines a method for forecasting the ideal values of the previously indicated scanning parameters. Based on the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 265–278 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article