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541 articles for “evaluation” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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Exploring The Multitarget Pharmacological Mechanism of Diabex for T2dm by Combining Network Pharmacology and Molecular Docking Techniques
Abstract: Objective: Hyperglycemia brought on by an absolute or relative absence of insulin synthesis or action characterises a set of illnesses known as diabetes mellitus. Chronic hyperglycemia in diabetes mellitus has been linked to organ damage, heart, and blood vessels. The persistent metabolic condition Diabetes is a severe global issue with negative social, health, and economic effects. It is a type of metabolism disorder that interferes with food digestion in the …
Published in International Journal of Bioinformatics and Computational Biology Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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A Study to Determine the Impact of a Structure Teaching Program on the Knowledge of Needle Stick Injury Among Hospital Staff Nurses
Abstract: Needle stick injuries occur when needles accidentally puncture the skin, posing a risk to individuals working with hypodermic syringes and other needle equipment, particularly in healthcare settings. These injuries are recognized as occupational hazards in the medical field and raise concerns about the potential transmission of blood-borne illnesses, including hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). Although the immediate physical effects of needle stick …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Youthful Students’ Perception of The Nursing Profession: A Preliminary Single-group Research
Abstract: Aim: This study had four objectives: (1) examine how adolescents perceive nursing before and after organized teaching programs; (2) examine how adolescents perceive nursing after structured teaching programs; (3) compare pre-test and post-test results to assess the efficacy of a structured teaching program; (4) relate the mean improvement in nursing image to particular demographic factors. Background: This study assists in identifying potential areas for improvement or any potential interventions to …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Energy performance analysis: An exploratory study of HVAC systems in efficient management of data centres
Abstract: Data center growth is being driven by the rapid proliferation of cloud services. Data centers are using an increasing amount of energy. The network is severely impacted by server workloads, cooling, and supporting equipment. The study aims to identify the energy consumption involved in building services and their operations and analyze the ways in efficient management of performance in data center. The objective of the study is to identify the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 51–71 Read article
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Exploration of 5-Hydroxybowdichione Flavonoids As Inhibitors of Dengue Virus Ns5 RNA-Dependent RNA Polymerase Using Molecular Docking Approach
Abstract: Objectives: Human lives are now seriously threatened by dengue fever, which is brought on by the dengue virus (DENV). Aedes aegypti mosquitoes, which reproduce in still water, are the primary vectors of the arboviral virus known as dengue. It is well-recognized that phytochemicals have a high potential to eliminate bacterial, viral, and fungal infections in people. Thus, it demonstrates its inhibitory effects on the dengue virus. This study identifies some …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 1–16 Read article
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ECZEMA {Atopic Dermatitis}
Abstract: Many of the persons around the world suffer from eczema which is also called atopic dermatitis. It is a kind of skin disorder that makes the skin dry, itchy, and sometimes even painful. There is no specific age group who got affected by this particular disease, no matter what age you are. But particularly it is seen that the children were mostly affected by eczema, as there is no cure …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 53–66 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article
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Searching Substring in O(n) Time Complexity
Abstract: This research paper presents a highly efficient algorithm for substring search within a given string, achieving a remarkable time complexity of O(n). The proposed algorithm utilizes a two-pointer approach to compare the given string with the targeted substring. By employing string concatenation, the algorithm dynamically constructs a resultant substring during the matching process. Upon completion of character matching, the algorithm compares the resultant substring with the targeted substring and returns …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 9–15 Read article
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Production of Disinfectant Using Aloe Vera (Aloe barbadensis miller) Plant Extracts
Abstract: This research work demonstrates the production of a disinfectant using aloe vera (Aloe barbadensis Miller) as main source of the raw material. The liquid content of the aloe vera was extracted using mechanical and unit operation mechanisms and the obtained raw material was subjected to heating to evaluate the effect of temperature on the characteristics of the physiochemical properties of pH, total ash, crude fat, fibre and protein, total carbohydrate, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 17–30 Read article
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Impact of Counseling on Cancer Patient’s Depression Level
Abstract: Introduction: When given the dreaded and possibly fatal cancer diagnosis, patients go through a great deal of pain. Depression is one of the psychiatric problems that can arise after a cancer diagnosis. The purpose of the current research is to evaluate how well counseling therapy can lower depression levels in cancer patients. Methodology: Geetanjali Hospital in Udaipur provided the data for this study, which utilized a single-group, quasi-experimental analysis employing …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 1–5 Read article
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A Study on Cancer Related Fatigue and Quality of Life (QOL) among Women Undergoing Treatment for Various Cancers in Selected Tertiary Care Hospitals of Ludhiana, Punjab
Abstract: Cancer is a collection of illnesses marked by irregular cell proliferation that has the potential to infiltrate or metastasize to different areas of the body. Gynecological cancer specifically refers to the abnormal cell growth in the female reproductive tract, including various organs such as the endometrium, fallopian tubes, ovaries, uterus, cervix, vagina, and breast. These cancer cells have a tendency to multiply uncontrollably. The majority of individuals diagnosed with cancer …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 6–11 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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A Study to Assess the Impact of Infertility on Marital and Sexual Satisfaction among Infertile Women Visiting Selected Infertility Clinics of City Ludhiana, Punjab
Abstract: Infertility has been described as a stressor and a life crisis for infertile women, which results in a lower marital and sexual satisfaction. More dissatisfaction is felt by infertile women, and both direct and indirect negative effects on the marriage are brought on by stress connected to infertility and its treatment. Having social support from family, a partner, and friends can help infertile women cope with a variety of stressors …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 7–12 Read article
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Usefulness of Video Assisted Education Programme Concerning Awareness on Management of Selected Nutritional Deficiency Disorders Among Mother of Adolescent Girls at Selected Rural Area of Kolar Taluk
Abstract: Background: With an estimated 190 million adolescents, 22% of whom are girls, India has one of the fastest increasing youth populations in the world. Adolescence, as defined by the WHO, is the period between the ages of 10 and 19, which provides a window of opportunity for improving nutritional status and reversing unhealthy eating habits. A growth spurt, or a time when growth is incredibly rapid, is what defines adolescence. …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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Wireless Sensor Network Localization Based on Static Anchor Node
Abstract: Anchor-based localization is a crucial challenge in wireless sensor networks (WSNs), aiming to determine the positions of all sensors by leveraging a limited number of anchor nodes whose locations are known. In this paper, we propose a novel algorithm for anchor-based localization in a static network, which improves the localization accuracy while reducing the computational complexity compared to existing methods. Our algorithm uses a range-based approach to estimate the distances …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 1, 2023 · pp. 12–20 Read article
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Card Fraud Detection Using Artificial Neural Network and Multilayer Perception Algorithm
Abstract: Fraud has posed a significant challenge for merchants, especially in the online business sector, over the course of many years. This is primarily due to the advancements in technology that have made credit card transactions a common method of payment. Credit card fraud refers to the unauthorized use of a credit card by an individual for personal purposes, without the owner's consent and with no intention of paying for the …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 1, Issue 1, 2023 · pp. 21–30 Read article
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Comparison of Different Models forthe Remediation of Crude Oil Contaminated Clay and Swampy Soil Environment
Abstract: This research was carried out to compare different mathematical models for the determination of best practice or method for remediation of crude oil contaminated clay and swampy soil environment. The results obtained were utilized to calculate the highest specific rates, the disassociation constant, and the kinetic values in terms of first- and second-order kinetics. The use of the Lineweaver Buck plot was taken into consideration for the different reactors, and …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 1–8 Read article