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304 articles for “chronic”
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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The Role of Optimism in Reducing Psychological Distress Amongst Women in Urban Areas
Abstract: This paper aims to explore the role of optimism in reducing psychological distress among women living in urban areas. Psychological distress, encompassing anxiety, depression, and chronic stress, has become increasingly prevalent due to the fast-paced and demanding nature of urban life. Women, in particular, face unique stressors including work-life imbalances, financial pressures, safety concerns, and societal expectations, which contribute significantly to elevated levels of mental strain. Finding healthy coping strategies …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 2, 2025 Read article
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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Pharmacology in Clinical and Therapeutic Settings
Abstract: Polypharmacy, which refers to the practice of taking many medications at the same time, is becoming more common among elderly populations as a result of the steadily increasing prevalence of chronic conditions. The clinical and therapeutic consequences of polypharmacy are investigated in this paper, with a particular emphasis placed on drug-drug interactions, altered pharmacokinetics, and patient safety. The physiological changes that occur with advancing age have a substantial impact on …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 51–58 Read article
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Next Generation Sequencing (NGS) in Personalized Medicine: Emphasizing Public Health Beyond Reality
Abstract: NGS is a modern technology that allows researchers to quickly sequence large amounts of DNA or RNA, it is also known as massively parallel sequencing or deep sequencing. NGS has revolutionized genomic research and biological sciences by its speed, scale, accuracy, ultra-high throughput, and cost. NGS replaced the conventional sequencing method. A novel idea in healthcare is precision medicine, which involves adjusting medical care to each patient’s unique traits and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Sensor and AI based Pre-Detection Systems Transfiguring Intoxication & Smoking
Abstract: The ubiquitous problems of drunkenness and uncontrolled smoking continue to pose substantial hazards to public health, safety, and productivity in a world that is becoming more linked and protective of its personal safety. The costs to society and the economy are substantial, and they range from automobile accidents caused by impaired driving to accidents that occur in the workplace, and from chronic health disorders that are connected to smoking to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 3, 2025 · pp. 37–50 Read article
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A Systematic Review on Peptic Ulcer Disease and its Pharmacological Treatment
Abstract: A chronic gastrointestinal condition known as Peptic Ulcer Disease (PUD) is typified by the formation of ulcers or mucosal erosions in the proximal duodenum and stomach. In the pathophysiology of PUD, the equilibrium between defensive processes like mucus and bicarbonate secretion, mucosal blood flow, and prostaglandin production, and aggressive factors such stomach acid secretion, pepsin activity, and Helicobacter pylori infection, is upset. Although stress and food have historically been blamed, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 76–84 Read article
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Microneedles: An Innovative Drug Delivery System
Abstract: Microneedles represent a groundbreaking innovation in drug delivery systems, offering a transformative alternative to conventional hypodermic needles and transdermal patches. This advanced technology combines the precision and efficacy of needle-based delivery with the convenience and pain-free nature of patches, creating a minimally invasive platform that addresses many limitations of traditional drug administration. Microneedles are designed to penetrate the stratum corneum – the skin’s outermost layer – without reaching pain-sensitive nerves …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 60–67 Read article
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Understanding the Cervical Spine Disorder: A Cross-sectional Survey Study
Abstract: Cervical spine disorders encompass a spectrum of conditions including degenerative spondylosis, disc herniation, traumatic injuries, and myelopathy that impair quality of life through chronic pain, neurological deficits, and functional limitations. Globally, neck pain affects over 200 million individuals, with an age-standardized prevalence of 2666 per 100000 population and an incidence of 816 per 100000 person-years, contributing to significant years lived with disability (YLDs). Economic analyses estimate annual direct healthcare costs …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 80–97 Read article
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Exploring the Therapeutic Potential of Phytochemicals in Aloe Barbadensis Miller Through Molecular Docking for Ulcerative Colitis Management
Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation of the colon, often associated with immune dysregulation and oxidative stress. Natural compounds have gained significant attention as alternative therapeutic agents due to their efficacy and minimal side effects. Quercetin, a flavonoid abundantly found in Allium cepa (onion), has demonstrated potent anti-inflammatory and antioxidant properties. This study employs an in silico approach to evaluate the therapeutic potential …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 06–12 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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Improving The Accuracy of Medical Diagonosis Detection Using Machine Learning
Abstract: While accurate and timely medical diagnosis is a fundamental aspect of effective health care delivery, traditional methods have not been able to overcome major hurdles such as inefficiencies in data analysis with Gi Human Error as well as limitations in scalability. The “Improved Accuracy of Medical Diagnosis Detection Using Machine Learning” project seamlessly integrates advanced machine learning (M L) technologies with efficient preprocessing and feature selection techniques to outperform all …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 1–8 Read article
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Revolutionizing Vaccine Development:The Transformative Role of Bioinformatics in Designing Next-Generation Immunotherapies
Abstract: Vaccines have long been central to the prevention and control of infectious diseases, dramatically reducing morbidity and mortality worldwide. In the modern era, the integration of bioinformatics has revolutionized vaccine development by enabling rapid, precise, and cost-effective identification of potential vaccine targets. This seminar explores the multifaceted applications of bioinformatics in vaccinology, including antigen discovery, epitope prediction, structural modeling, molecular docking, and immunoinformatics-driven vaccine design. Special emphasis is placed on …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 19–33 Read article
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Efficacy of Selected Yoga Practices on WHO – Quality of Life (BREF) With and Without Modified Diet and Lifestyle in Healthy Adults
Abstract: Quality of life (QoL) is crucial as it balances physical health, mental well-being, and emotional satisfaction, which are often compromised by people. Prioritizing QoL enhances overall happiness and productivity, reduces chronic health issues, and fosters stronger social connections. It is a multidimensional concept that has a direct impact on physical, psychological, and social well-being. The prevalence of QoL is influenced by factors, such as economic conditions, healthcare access, education, and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 1–9 Read article
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Ayurveda as a Medium of Healing: A Critical Review of Classical Concepts and Modern Evidence
Abstract: Ayurveda, recognized as one of the world’s oldest holistic healing systems, has its origins in India over 5,000 years ago. Rooted in a philosophy that views health as a harmonious balance of body, mind, and spirit, Ayurveda offers a comprehensive and individualized approach to wellness. This traditional system of medicine is grounded in the concept of the Tridosha Vata, Pitta, and Kapha representing the fundamental bio-energetic forces governing physiological and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 40–44 Read article
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A Study on AI-Enhanced Environmental Toxicology: Sensor-Driven Predictive Framework
Abstract: Traditional environmental toxicology relies heavily on labor-intensive, often retrospective, sampling and analysis, limiting our understanding of dynamic pollutant behaviors and their real-time impact on ecosystems and human health. This study presents a novel, integrated framework leveraging advanced sensor networks and artificial intelligence (AI) to revolutionize the monitoring, assessment, and predictive modeling of environmental contaminants. We deployed a sophisticated array of multi-parameter sensors (e.g., electrochemical, optical, biosensors for heavy metals, organic …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 Read article
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AI and Sensor Systems Revolutionizing Intoxication and Smoking Pre- Detection
Abstract: In an increasingly interconnected and safety-conscious world, the pervasive issues of intoxication and uncontrolled smoking continue to pose significant threats to public health, safety, and productivity. From impaired driving incidents to workplace accidents, and from chronic health conditions linked to smoking to the risk of fires, the societal and economic costs are staggering. However, a new frontier in preventative technology is emerging: sophisticated AI and sensor-based systems designed for the …
Published in Journal of Control & Instrumentation · Vol. 16, Issue 3, 2025 · pp. 14–25 Read article