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419 articles for “Uses Pharmacological”
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Herbal Medicine in Unani Tradition: Managing Depression from A Holistic Perspective
Abstract: Depression is a prevalent mental health condition marked by persistent sadness and a loss of interest in once- enjoyed activities, often accompanied by an inability to carry out daily tasks, lasting for at least two weeks. In the field of Unani medicine, this disorder falls under the category of "Nafsiyati awamil," with its classical description referred to as "Malenkholiya" or melancholia. According to the World Health Organization (WHO), depression ranks …
Published in Research & Reviews : Journal of Herbal Science · Vol. 12, Issue 3, 2023 · pp. 1–6 Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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Factors Contributing to Pharmacological Compliance Among Hypertensive Clients
Abstract: Control of hypertension requires good deal of compliance with the prescribed therapeutic regimen of drugs. Nurses have a unique role to play in monitoring compliance and to study factors leading to non-compliance for chronic diseases like hypertension. The present community based study was conducted among 100 diagnosed cases of hypertension in an urban area of Amritsar, Punjab by using pill count method. The findings of the study depict that 45% …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 1, 2015 · pp. 32–35 Read article
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Remedial Prospective of Vitis vinifera in Unani System of Medicine: An Overview
Abstract: Vitis vinifera Linn belonging to the family Vitaceae is known as Angoor in Unani and Draakshaa in Ayurveda system of medicine. It is found in North-western India especially Bengal, Himachal and Andhra Pradesh. The plant contains malic acid, tannic acid, flavonoids, tartrates, inositol, carotenes, choline and sugars. It has been used in traditional systems of medicine since centuries for the treatment of diseases like bilious dyspepsia, dysuria, cholera, nausea, fever, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 2, 2014 · pp. 18–22 Read article
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A Review on Pharmacological Activities and Phytochemical Studies of Quisqualis Indica Linn
Abstract: This article contain brief review of pharmacological study and phytochemical study of plant Quisqualis Indica Linn, the point which have to be considered that this plant can be available easily as it is an evergreen plant and most of the people were used to decorate their houses, as this is an ornamental plant too which doesn’t depend on seasons to grow. Quisqualis indica Linn contains phytoconstituents such as trigonelline (alkaloid), …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 32–36 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions.Methods: A total of twenty-seven …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article
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Clinical Trials: A Brief Review
Abstract: Clinical trials, according to the World Health Organization, are used to test new medicinal entities on humans after they have been studied in animals. Clinical studies are usually divided into five stages. Clinical pharmacologists study phase I pharmacokinetics, safety, and gross effects on human volunteers. If the drug passes the test, it moves on to phase II testing, where pharmacokinetics, safety, and therapeutic efficiency are studied on a small number …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 1, 2022 · pp. 1–7 Read article
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Study-based Pharmacological Appraisal of Commiphora myrrha
Abstract: Myrrh is a highly aromatic resin exuded from the bark of various species of the Commiphora genus, such as Commiphora myrrha, Commiphora molmol, and Commiphora abyssinica. The name “Commiphora” is derived from the Greek words “kommi” and “phero” meaning “gum-bearing.” These trees are mainly found in arid regions of the Middle East and Africa. The resin is harvested by making incisions in the bark and allowing the sap to dry …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 3, 2023 · pp. 29–38 Read article
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A Combined Molecular Docking Analysis of The Phytochemicals of Ginkgo biloba against The Parkin Protein Target (Autoinhibited Parkin Catalytic Domain)
Abstract: This study's goal is to evaluate the specific therapeutic targets for Parkinson's disease (PDB ID: 4BM9) using molecular docking simulation and ADME analysis against bilobalide, quercetin, ginkgolide B, and protocatechuic acid (3,4-Dihydroxybenzoic acid). The Protein Data Base was used to extract theprotein's three-dimensional structure, and the PubChem database was used to retrieve the ligands. Using Auto-Dock Tools-1.5.7, a molecular docking simulation of the compounds was carried out. Since none of …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 1, 2023 · pp. 1–9 Read article
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Comparative Study of Medicinal Properties of Indigenous Drugs from Species of Strychnos L. and its Scope in the Field of Homoeopathy- a Pilot Study
Abstract: AbstractPlant kingdom is a rich source of drug. Different medical systems prepare drug from plants and employ them according to their own pharmacological principles. Genus Strychnos L. belongs to Loganiaceae family and contains many active principles like brucine, strychnine, icajine, toxiferine, loganine, etc. Modern medicine and AYUSH use genus Strychnos L. to prepare drug against several disease conditions like ulcers, neurological disorders, skin diseases, parasitic infestations etc. Work has been …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 1, 2020 · pp. 13–19 Read article
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Cancer Prevention Activity in Vitro and the Mechanism of Action Bioactive Ingredients
Abstract: Natural substances that can treat a variety of ailments, including cancer, can be found in the Solanaceae plant family. There is still uncertainty regarding the location and mode of action of these substances in cells. Several of the cellular targets can now be studied and identified thanks to increasing advances in biological science research. The relevant studies that describe how some of these substances may fight cancer are found in …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 20–25 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Literature Review of Irsal-e-Alaq (Leech Therapy) in Unani and Modern Science
Abstract: The Unani system of medicine is based on the humoral theory (Nazriya Akhlat) postulated by Buqrat. According to this theory, all illness is caused by an imbalance of one of the four body humors that is, blood, phlegm, yellow bile and black bile. Irsal-e-alaq is one of the oldest and widely practiced means of Ilaj-bit-tadbeer for local evacuation of morbid humours. It is a procedure of treatment with the use …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 21–29 Read article
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A Process for Standardization of Ayurvedic Polyherbal Formulation (Churna) for Antioxidant Activity
Abstract: Ayurvedic medicinal preparation as per Ayurveda by using herbal antioxidant ingredients; the name of prepared formulation in Ayurveda is called churna, That churna having antioxidant property known to be effective in all types of allied disorders also, related to oxidation in cellular and molecular level in a living system has been standardized by following modern scientific quality control procedures both for the raw material and finished product. The obtained values …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 2, 2014 · pp. 1–7 Read article
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A Review on Citrullus lanatus
Abstract: Citrullus lanatus is an herbaceous climbing plant and belongs to Cucurbitaceae family. It is commonly known as watermelon. It is grown in a variety of temperatures around the world. Economically it is growing very well in the word. The fruit is high in the antioxidants, lycopene and carotenoids. It helps to neutralise free radicals in our body. Watermelon seeds are high in vitamins B, protein, minerals and phytochemicals, among other …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 10, Issue 3, 2021 · pp. 12–15 Read article
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To Estimate the Antibacterial Activity of Piper Nigrum Extract
Abstract: A natural remedy called piper nigrum is used to cure a variety of illnesses. It is employed in conventional herbal medicine for a number of therapeutic applications. Alkaloids, tannins, phenolics, and other phytochemicals can be found in Piper nigrum leaf tissue. In different places, medicinal plants are employed as a source of several effective and strong medications and are a rich supply of antibacterial compounds. The main chemical component that …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 10, Issue 2, 2023 · pp. 62–74 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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Anti-nociceptive Potential of Scurrula parasitica: An Unexploited Parasitic Plant
Abstract: Scurrula parasitica (Loranthaceae) is an herbaceous growing shrub parasitic on Dendrophthoe falcata (Loranthaceae) which is itself parasitic on Mangifera indica (Anacardiaceae). Scurrula parasitica is distributed throughout the western ghat region of Maharashtra, some parts of Uttar Karnataka and Tamil Nadu. Genus Scurrula comprising of around 91 species, however, only S. ferruginea, S. atropurpurea, S. fusca have been investigated systematically. No such pharmacological and phytochemical data are available on the plant …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 · pp. 4–8 Read article