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412 articles for “PKA/CREB pathway”
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Development of Self-Healing Circuit Boards Using Shape Memory Polymer Composites
Abstract: This study investigates the influence of temperature, humidity, and nanofiller type on the electrical and structural performance of advanced polymer nanocomposites for self-healing circuit applications. Particular attention was given to conductivity retention and the morphological behavior of carbon nanotubes (CNTs), graphene, and silver nanoparticles (AgNPs). Results show that conductivity decreased under elevated thermal–humidity conditions, reflecting the role of environmental stress in material degradation. Among the tested systems, AgNP-based composites achieved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 746–770 Read article
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Photonic Polymer Composites for Light-Modulating Displays and High-Throughput Optical Data Transmission
Abstract: The combination of PMMA-based composites recently received substantial attention from the photonic applications field since these materials combine excellent optical transparency, mechanical flexibility and straightforward fabrication capabilities. The material performance of pure PMMA requires functional additives because it shows limited thermal properties and optical attenuation in addition to sensitivity against UV rays. The research explores developmental pathways for PMMA composites through combined use of nanoparticles and electro-optic polymers with dopants …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 838–860 Read article
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Nanostructured Catalysts for Sustainable CO2 Reduction: Advancing Green Chemistry and Polymer Composites
Abstract: Artificial photosynthesis is the advancement of a process that utilizes sunlight to convert CO₂ and H₂O into high-energy fuels (methanol, hydrogen) analogous to photosynthetic pathways. Carbon-neutral energy is critical to tackling climate change, and this method provides a solution by offering an alternative to fossil fuels while also minimizing greenhouse gas emissions. Nanostructured catalysts such as plasmonic metals and hybrid nanocomposites greatly improve efficiency and scaling. Recent developments in the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Dynamic Mechanical Analysis of Carbon Fiber Reinforced Polymer Composites
Abstract: This study investigates the thermal decomposition and mechanical properties of Fiber-Reinforced Polymer Composites (FRPCs) using Dynamic Mechanical Analysis (DMA). The research focuses on improving the recycling and recovery process of Carbon Fiber-Reinforced Polymers (CFRPs), addressing environmental concerns regarding their disposal. By analyzing the effects of different heating rates (5°C and 10°C per minute) and atmospheric conditions (nitrogen, oxygen, and a combination of both), the study identifies optimal parameters for maximizing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 386–393 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Multifunctional Materials for Electro-Mechanical Applications: Synergistic Integration of Strength and Conductivity
Abstract: The integration of mechanical strength and electrical conductivity within a single material system has emerged as a critical requirement in the development of next-generation multifunctional materials. These materials are increasingly sought after in fields such as aerospace, flexible electronics, energy storage, and structural health monitoring, where the traditional separation of structural and functional materials leads to inefficiencies in weight, space, and overall performance. The convergence of these properties enables compact …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Accelerating Unsupervised Feature Learning: Parallelized Training of Denoising Autoencoders
Abstract: Unsupervised representation learning has become a cornerstone of contemporary machine learning, enabling algorithms to extract informative features from un-labelled, high-dimensional data. This work investigates the efficacy of stacked denoising autoencoders (SDAEs) trained via parallelized stochastic gradient descent (SGD) as a scalable approach to feature extraction. By strategically leveraging multi-threaded computation, our study systematically examines the trade-offs between increased parallelism, training efficiency, and the preservation of model accuracy. Experiments on the …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 3, 2025 · pp. 56–64 Read article
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Ecological, Economic, and Medical Roles of Fungi: Insights from Mycology in Addressing Global Challenges"
Abstract: The large and diverse kingdom of fungi is vital to ecosystems, industry, agriculture, and medicine. Due to its ecological and biotechnological value, mycology has grown in importance. Fungi are crucial to natural systems and human life, decomposing organic materials, developing mutualistic interactions with plants, and producing antibiotics and fermented products. Recent advancements in molecular biology and genomics have significantly enhanced our understanding of fungal diversity, physiology, and evolutionary processes. These …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
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Exploring the Therapeutic Potential of Ilāj-Bil-Ghizā (Dietotherapy) in Depression: A Systematic Review
Abstract: Background: Depression is a common mental health condition characterized by feelings of sadness, diminished interest in activities, and physical symptoms that disrupt daily activities functioning. Emerging research indicates that nutrition and dietary habits can significantly influence the management of depression. This review aims to explore the connection between diet and mental health, highlighting how nutritional approaches may complement traditional treatments for depression. Objective: This review aims to evaluate the relationship …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 10–18 Read article
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Dual-Stream Deep Learning Framework for Brain CT Image Classification and Implications for Polymer Composite Neuro Implant Evaluation
Abstract: Early and accurate classification of brain CT images is critical for diagnosing conditions such as aneurysms, tumors, and related lesions. We present a dual-stream image-classification framework that fuses convolutional neural network (CNN) features with handcrafted Histogram of Oriented Gradients (HOG) descriptors to jointly capture global semantics and local textural cues. The pipeline begins with modality unification via pixel-wise averaging to form a fused input, which is then processed in parallel …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 172–179 Read article
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Automated Blood Cell Counting and Disease Identification Using Image Processing: Implications for Polymer Composite- Based Biomedical Diagnostic Devices
Abstract: Accurate quantification of blood cells is central to clinical decision-making and to the performance of emerging polymer composite–based diagnostic platforms. This work presents a cost-effective, image-processing pipeline for automated counting of red blood cells (including overlapping cells), white blood cells, and platelets from Leishman-stained peripheral blood smears, and articulates its relevance to polymer composite microfluidic and biosensor devices. Implemented in Python with OpenCV, the workflow performs grayscale conversion, median/Gaussian denoising, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 262–270 Read article
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Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name ‘Hematologic cancer’ have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from lymphatic system resulted in uncontrolled growth and instead of normal apoptosis development of tumor. Myeloma, uncontrolled formation of malignant plasma cells leads disrupting production of healthy blood cells. This situation creates variety of diseases like anaemia, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Lesser-Known Metabolites Influencing Ovarian Function, Follicular Development, and Embryo Viability in Dairy Cows
Abstract: The intricate processes of ovarian function, follicular development, and embryo viability in dairy cows are tightly regulated by a complex network of metabolites. While conventional biomarkers, such as steroid hormones, amino acids, and glucose metabolites, have been extensively studied, a growing body of evidence suggests that lesser-known metabolites play pivotal roles in bovine reproductive physiology. Dairy cattle fertility is critical for maintaining optimal milk production and herd sustainability, necessitating deeper …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 18–29 Read article
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Artificial Intelligence and Personalized Learning
Abstract: Artificial Intelligence is transforming education by delivering customized learning pathways that align with each learner’s unique abilities and areas for improvement. Traditional teaching often struggles to meet individual needs; however, AI-powered systems analyse learning patterns in real time, ensuring customized lessons. Virtual tutors and AI chatbots provide instant feedback and 24/7 support, improving comprehension. Gamified learning, combined with augmented and virtual reality, transforms education into a more engaging and enjoyable …
Published in Current Trends in Information Technology · Vol. 15, Issue 3, 2025 · pp. 11–18 Read article
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Disease Prediction Using Ensemble Learning Models: A Comprehensive Approach
Abstract: In recent years, ensemble learning techniques have become pivotal in advancing predictive analytics within healthcare, particularly for early disease detection. The inherent variability and complexity of medical data, often characterized by high dimensionality, class imbalance, and noise, make it challenging for standalone classifiers to maintain high predictive accuracy. Ensemble learning, by integrating multiple models through bagging, boosting, or stacking, offers a more robust and generalizable approach. This study explores the …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 3, 2025 · pp. 26–33 Read article
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Generative AI for VR: Creating Physically Realistic Models
Abstract: Virtual Reality has revolutionized the traditional learning system by creating and interactive and engaging environment. However, its ability to show precise real-world experiences is limited due to lack of physical realism. This study investigates the potential of Generative Adversarial Network (GAN) in creating physically realistic 3D models. Proposed system incorporates deep learning techniques along with physics-based constraints to enhance model’s accuracy and usability. To achieve this, experiments were conducted on …
Published in Journal of Advancements in Robotics · Vol. 12, Issue 3, 2025 · pp. 14–22 Read article
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Gene Editing in Dairy Cows: Advancing Milk Yield, Health, and Resilience for Sustainable Dairy Development
Abstract: Gene editing has emerged as a transformative tool in dairy science, offering unprecedented opportunities to enhance productivity, improve animal health, and bolster resilience against environmental challenges. This study explores the potential of gene editing technologies, including CRISPR-Cas9, in advancing milk yield, optimizing milk composition, and addressing genetic disorders in dairy cows. Specific applications include targeting genes associated with mastitis resistance, improving feed efficiency, and introducing heat tolerance traits to adapt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Role of Food Supplements in Premalignant Lesions: A Literature Review
Abstract: Premalignant lesions of the oral cavity are histopathological alterations in the oral epithelium linked to a higher likelihood of malignant transformation. These lesions frequently present as leukoplakia (white patches), erythroplakia (red patches), oral lichen planus, and oral submucous fibrosis. Oral cancer, categorized among head and neck malignancies, is considered the sixth most common cancer globally. While tobacco and alcohol consumption remain the primary etiological factors, increasing evidence underscores the significant …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 17–26 Read article