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1908 articles for “HIV-1 Integrase” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Lamivudine And Dolutegravir Simultaneous Dosage Forms Determined and Validated Using The RP-UPLC Method
Abstract: RP-UPLC has been used to produce a straightforward, precise, and accurate approach for the simultaneous estimation of dolutegravir and lamivudine in a pharmaceutical dose form. A HSS C18 column of 2.8 x 50 mm and featuring particles with a size of 1.6 μm was used to process the chromatogram. A mixture of 70:30 Buffer Na2HPO4 and methanol made up the mobile phase, which was pushed across the column at a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 5–13 Read article
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Experimental Investigation of Mechanical Properties of the Composite Materials Reinforced by Agro-based Waste Materials
Abstract: In this work, experiments were carried out to develop the glass fiber reinforced composites using the hand layup method and analyze the mechanical properties of the GFRP hybrid composites. The ultimate Tensile strength (UTS) using rice as a filler (GFRPC/R) was 3.04% and 12.89% higher than coir and wheat as filler, respectively. The hybrid composite using coir as a filler (GFRPC/C) revealed 12.54% greater flexural strength, and the hybrid composite …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 186–196 Read article
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Assessing the Permeability of Bentonite with Sand, Marble Dust, and Fly Ash mixture with and without Effect of Permeate Solution for the Development of Efficient and Cost-Effective Landfill Liner for Sustainable Waste Management and Environmental Preservation
Abstract: This exploration paper researches the capability of further developing landfill liner materials by integrating varying percentages of bentonite into sand, marble dust, and fly ash mixtures. The study focuses on determining whether these mixtures are suitable for development of landfill liner by examining their permeability properties. Bentonite, a clay known for its high swelling and sealing properties, is added to sand, marble dust, and fly ash at different range from …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 1–11 Read article
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Hidradenocarcinoma: A Rare Skin Disease
Abstract: Hidradenocarcinoma (HAC) also known as ‘‘sweat gland tumor” is an aggressive, uncommon, highly malignant, adnexal tumor derived from the intradermal duct of eccrine sweat glands. It is said to be aggressive as it has a high risk of local recurrence (50%–75%) and a high potential to metastasize to nearby lymph nodes or to other distant sites. Hidradenocarcinoma has other recognized variants which are known by different names such as Malignant …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 1–12 Read article
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Effect of Compressive Strength of Core and Precast Concrete on the Behavior of Column Retrofitted by Precast Segment and FRP Wrapping - A Finite Element Study
Abstract: In the present investigation the effect of compressive strength of core and precast concrete on the behavior of columns retrofitted by attaching precast segments and followed by FRP wrapping through Finite Element Analysis. A rectangular column converted into an elliptical column by attaching precast segment is modeled using ANSYS workbench, A Finite Element Analysis software. A Finite Element Model is developed, considering various structural parameters such as grades of core …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 302–310 Read article
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Unveiling the Engine of Efficiency: Exploring the Vital Dimensions of Warehousing for Optimal Operational Performance
Abstract: This research endeavours to comprehensively explore the multifaceted dimensions of warehousing that significantly influence operational efficiency within the bustling industrial nexus of the National Capital Region (NCR), encompassing a diverse array of warehouse types in the vicinity of Delhi-NCR. Employing a meticulously crafted structured questionnaire, respondents provided insights through a Likert scale, ranging from 1 = Strongly Disagree to 5 = Strongly Agree. The data collection process, utilizing stratified sampling …
Published in Journal of Production Research & Management · Vol. 14, Issue 1, 2024 · pp. 29–38 Read article
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A Study on Determination of Seismic Susceptibility in Existing Buildings in Ward No-18 of Dhaka North Using Rapid Visual Screening (RVS) Method
Abstract: The research work presents a comprehensive analysis of the Rapid Visual Screening (RVS) method applied to 200 buildings in Ward No. 18 of Dhaka North City. The study focused on assessing the seismic vulnerability of these structures, categorizing them into damage grades based on the RVS evaluation. Strikingly, the findings revealed that 191 out of the 200 buildings were classified as damage grade 5, signifying severe structural deficiencies. In contrast, …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 28–37 Read article
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Remediation of Condemn Oil Polluted Loamy Soil Using Azadirachta Indica (Neem)
Abstract: The remediation of condemn oil polluted loamy soil using neem (azadirachta indica) was investigated. The neem leaves came from Akpugo in the southeast Nigerian state of Enugu State's Nkanu West local government area. The leaves were dried at room temperature and subjected to grinding machine to obtain the powdered form of the dried leaves that serve as treatment to remediate condemn oil polluted loamy soil. Three masses 5g, 10g and …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 21–27 Read article
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A study to access the knowledge of adolscents’s girls prevention of iron deficiency anemia in modern government girls inter college pantnagar U.S.,nagar, uttarakhand with a view to develop an information booklet on prevention and management of iron deficiency anemia
Abstract: A study was conducted at Modern Government Girls Inter College in Pant Nagar, U.S. Nagar, Uttarakhand, aiming to assess adolescent girls' knowledge of preventing iron deficiency anemia and to develop effective educational materials. The research employed a non-experimental design, selecting a sample of 100 adolescent girls through convenient sampling. Data collection involved two parts: Part A covered demographic variables, while Part B consisted of a 32-item knowledge questionnaire on anemia …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 44–53 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Current Perspectives of Prader -Willi Syndrome: A Multisystem Approach
Abstract: Prader-Willi syndrome (PWS) is a genetic disorder with multisystem involvement, caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region from paternal 15q11-q13 deletions (about 60%) or maternal uniparental disomy 15 or both. It is a complex and contiguous gene disorder which affects the multiple systems with many clinical presentations especially hypothalamic insufficiency. The clinical features are characterized by short stature position, developmental delay, cognitive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 42–48 Read article
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Effects of the Embryonic Bisphenol an Exposure on The Postnatal Development, Learning and Memory of Rat Offspring: Fundamental Study
Abstract: We studied the morphologic changes in some organs and changes of learning and memory of the rat offspring after the embryonic bisphenol A exposure. Background: Bisphenol A, widely used as polycarbonate plastics material to manufacture food packaging, toys, glasses, computers, kitchen utensils and medical instruments, is one of the most common endocrine-disrupting chemicals. It is demonstrated that bisphenol A may be mingled with foodstuff and beverage from package and receptacle. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 58–63 Read article
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A Study On Improving The Performance Of Concrete Using Coconut Fibers
Abstract: The aim of this study is to explore the incorporation of coconut fiber into M30 grade concrete and assess its impact on the strength characteristics. A literature review of different fibers is conducted and highlighting the working parameters. This research focuses to explore the efficacy of employing coconut fibers as micro reinforcement in concrete. The investigated properties encompass the compressive strength of the coconut fibers reinforced concrete (CFRC) at different …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 26–36 Read article
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IUCN Conservation Status and Global Population Trends of Avifauna in Pong Dam Lake Wildlife Sanctuary, Himachal Pradesh
Abstract: The expansive wetland at Pong Dam Lake, which is located within the picturesque Kangra district of Himachal Pradesh, stands out prominently as one of the largest artificially created wetlands in the entire region. This wetland is renowned for its biodiversity, particularly its avian population. In a comprehensive survey an impressive total of 225 bird species residing within the Pong Dam Lake Wildlife Sanctuary were documented. These species are spread across …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 3, 2024 · pp. 13–23 Read article
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A Comparative Analysis of Factors Contributing to Relapse in Alcohol and Opioid Dependence Among Patients Admitted to Selected Hospitals in Ludhiana, Punjab.
Abstract: Introduction: Substance abuse involves the dangerous or detrimental use of psychoactive substances, such as alcohol and illegal drugs. The use of these substances can result in dependence syndrome, which encompasses a range of behavioral, cognitive, and physiological effects that arise from ongoing substance use. Objectives: This study was carried out to examine the factors linked to relapse in alcohol and opioid dependence among patients admitted to selected hospitals in Ludhiana, …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Investigating the Occurrence and Damage of Wild Pig (Sus scrofa) in Cassava Ecosystems of Kerala
Abstract: The study investigates the occurrence and impact of wild pigs on cassava crops in selected locations of Thrissur and Palakkad districts of Kerala, spanning from July 2022 to May 2023. Data were collected from 10 sites, where each 1-acre field was divided into 5 quadrants for monitoring. The presence of wild pigs was tracked weekly through pug marks, infrared cameras, and farmer reports, while the extent of cassava plant damage …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 16–20 Read article
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Foundation in Weak Soil
Abstract: In geotechnical engineering, it is crucial to evaluate the interaction between structural loads and soil properties to ensure the stability and safety of foundations. In this scenario, the column is subjected to a load of 120 tons, with an additional 10% safety factor added, resulting in a total load of 132 tons at the foundation base. The foundation base is designed with dimensions of 2.5 meters by 2.5 meters, and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 47–52 Read article
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Assessing Supportive Care Needs Among Breast Cancer Survivors: A Cross-Sectional Study
Abstract: Breast cancer poses a significant global health challenge and ranks among the primary causes of cancer-related morbidity and mortality worldwide. The objective of this study was to evaluate the supportive care needs of survivors of breast cancer and examine how these needs are related to various background factors. To accomplish this, a cross-sectional study was carried out with 116 breast cancer survivors, selected using a convenient sampling method. Data were …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 39–42 Read article
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Exploring Muscle Energy Technique as A Physiotherapeutic Intervention for Peripheral Facial Palsy: A Pilot Report
Abstract: Background: Peripheral facial palsy results from damage to the peripheral branches of the facial nerve, often presenting as a sudden weakness in the muscles on one side of the face. Research on the application of muscle energy technique (MET) for treating this condition is scarce. Therefore, the aim of this study was to assess the effectiveness of MET in the treatment of peripheral facial palsy. Methods: 15 patients suffering from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 21–29 Read article