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235 articles for “Clinical Safety”
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Prospective Evaluation of the Optimal Concentration and Effect of Epinephrine as an Adjuvant to Local Anesthetics for Prolonging Block Duration and Reducing Systemic Toxicity in Outpatient Surgery
Abstract: Purpose: To evaluate the optimal concentration and effect of epinephrine as an adjuvant to local anesthetics for prolonging block duration and reducing systemic toxicity in outpatient surgery. Methods: The study involved a randomized double-blind clinical trial on 80 adult patients awaiting day-care extremity surgery. The patients were randomly assigned to two groups of equal size. One group, Group E, was given the local anesthetic agent along with epinephrine as an …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 64–69 Read article
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Healthcare Management with QR Code Using Blockchain
Abstract: The existing healthcare management system is heavily reliant on paper-based records and centralized databases. This makes it difficult to securely share patient data between healthcare providers, resulting in delays in treatment and potential errors in diagnosis. Furthermore, the current system is prone to cyber-attacks and data breaches, putting patient privacy at risk. The lack of transparency also leads to distrust between patients and healthcare providers. A quick response (QR) code …
Published in Recent Trends in Programming languages · Vol. 10, Issue 2, 2023 · pp. 36–42 Read article
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Vaccine Candidates and Animal Models for Kala-Azar
Abstract: Kala-azar or Visceral Leishmaniasis (VL) is a serious human disease in tropical regions and rapidly emerging as an opportunistic infection in HIV patients. The available treatment against VL is associated with toxicity and drug resistance. Even though the development of vaccines against VL is received limited attention. The only successful immunization strategy in humans has been leishmanization, which is based on the development of durable immunity after recovery from infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 29–35 Read article
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Gene Therapy 2.0: Harnessing Cutting-Edge Technologies for Precision Medicine
Abstract: Somatic gene therapy has become the standard form of gene therapy; this creates the Gene Therapy 2.0 era. This new and distinct time consists in the new-generation genome-editing tools and markers, more efficient systems for gene delivery, and personalized medicine approaches that raise the efficacy and safety of the treatment. Base and prime editing are two types of CRISPR-based gene editing tools have provided high precision and reduced off-target effects …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Signal Transduction Pathways in Xenotransplantation: Insights and Implications
Abstract: In this article, we will discuss Xenotransplantation which is used for the transplantation of tissues or organs cells from one species to another species. It holds tremendous promise for addressing the clinical shortage of human organs for transplantation. In this review we provide a comprehensive analysis of the key signal transduction involved in xenotransplantation is paramount for overcoming these hurdles and advancing the field toward clinical application. Many studies on …
Published in Current Trends in Signal Processing · Vol. 13, Issue 3, 2023 · pp. 15–23 Read article
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Carboxymethyl Cellulose-Based Spray-Dried Microspheres: Recent Advances and Applications in Targeted Drug Delivery Systems
Abstract: Microspheres are spherical particles ranging from 1 to 1000 μm, made from natural or synthetic polymers and inorganic materials. Their structure allows precise drug delivery, improving targeted release and minimizing off-target effects. Natural polymers such as starch, chitosan, and alginate are favored for their biodegradability, adhesion, and compatibility, enhancing mucosal interaction and residence time. Microspheres are widely used in site-specific drug delivery, gene therapy, and vaccine administration, improving immunogenicity, extending …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 251–268 Read article
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A Secure System of Health Care Service
Abstract: A Secure System of Health Care Service is a platform that stores patient information in an orderly way to aid in proper patient diagnosis and treatment. The current manual system has various issues, including: Delayed patient record retrieval, The duplicated records of patients, A lack of safety and Ineffective backup procedures for medical records. Although the Internet has long served as a reliable source of medical information, only recently has …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 03, 2022 · pp. 43–49 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Factors Affecting Mammalian Embryo Culture: A Detailed Review
Abstract: Human IVF has made remarkable progress, but optimizing the in vitro environment remains essential and crucial for supporting embryo development and improving overall clinical outcomes in assisted reproductive technologies (ART). Even with advances in complex culture media, incubator design, and laboratory workflows, embryos grown outside the body are still exposed to chemical and physical stressors that can significantly affect their developmental potential. In this review, we discuss key chemical stressors, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 · pp. 1–11 Read article
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Knowledge and Implementation of Infection Control Measures Among Nurses Caring for Patients with Chemical Gas Exposure
Abstract: The purpose of this study was to evaluate the level of knowledge and the extent of implementation of infection control measures among nurses caring for patients exposed to chemical gases. A descriptive cross-sectional design was adopted, and a sample of staff nurses working in clinical settings with potential chemical exposure roles was selected using convenience sampling. Data were collected via a structured questionnaire assessing knowledge of chemical inhalation hazards and …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 56–60 Read article
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Intelligent Failure Detection in Biomedical Composite Materials Using Machine Vision
Abstract: The biomedical composite materials are intelligent failure-detecting, which is necessary to ensure the reliability, safety, and durability of the current healthcare equipment. This paper describes a machine vision design, which incorporates convolutional neural networks, transformer models, and ensemble learning to correctly detect and localize material defects. The proposed system takes advantage of the capabilities of high-resolution imaging, advanced preprocessing software, and deep feature learning in the identification of the intricate …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Pharma Guard: Smart Medication Management System
Abstract: Pharma Guard Smart Medication Management System presenting a comprehensive overview of an innovative technology designed to revolutionize medication management in healthcare settings. In an era of advancing digital solutions, the Pharma Guard system offers a sophisticated approach to ensuring medication safety and adherence. Through the integration of smart technology, including internet of things (IoT) devices and machine learning algorithms, Pharma Guard enables real-time monitoring, tracking, and management of medication consumption …
Published in International Journal of Mobile Computing Technology · Vol. 2, Issue 1, 2024 · pp. 30–37 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 · pp. 60–78 Read article
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A Research Project on Identification and Reporting of Adverse Drug Reactions in General Medicine Ward of an ESI Hospital
Abstract: Aim: The study aims at identifying and reporting the adverse drug reactions (ADRs) in general medicine ward of an ESI hospital, Bangalore, Karnataka, India. Objective: Prescription study, analysis and prevention of medication-related problems (ADRs), identifying and minimizing medication-related problems, improving patient safety initiatives, improving the patient health-related outcomes, reducing work burden of physicians, and providing better therapy to large number of patients. Methodology: Study Design: It was a prospective and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 9–14 Read article
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Evaluating Linezolid: A Comprehensive Analysis
Abstract: Treatments for infections caused by Gram-positive bacteria, such as methicillin-resistant staphylococci and VRE, including skin and soft tissue infections, community-acquired pneumonia, and other infections treated with linezolid, an oxazolidinone antimicrobial agent that functions by specifically inhibiting protein synthesis. Even while antibiotic resistance is becoming more frequent in many nations, linezolid resistance among these pathogens is still low, typically less than 1%. Thus, the emergence of resistance in clinical isolates should …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 11–16 Read article