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791 articles for “CHO”
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A Case Report of Advanced Periampullary Carcinoma: Palliative Chemotherapy Following Whipple’s Surgery
Abstract: This case report delves into the complex management of a 60-year-old female patient diagnosed with Stage 4 periampullary carcinoma, encompassing the pancreatic head. Presenting with difficulty in eating, diagnostic investigations, including ERCP, confirmed the diagnosis, leading to Whipple's surgery. Postoperatively, liver metastasis was identified, prompting palliative intervention through stenting and the initiation of a GEMOX chemotherapy regimen. The patient responded favorably to the initial chemotherapy cycle, leading to a planned …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Evaluating the Use of Antibiotic Prophylaxis in Surgical Procedures: A Study Conducted at a Tertiary Care Teaching Hospital in Southern India
Abstract: Background: Prophylactic antibiotics can reduce the frequency of postoperative wound infections. Well-designed trials have demonstrated that the appropriate administration of prophylactic antibiotics in surgeries can reduce postoperative infections to about one-half of the incidence in untreated patients. Objectives: To examine surgeon's adherence to the hospital's antibiotic policy by comparing and assessing the usage of antibiotics as prophylactic before surgery. Methods: A prospective observational study was carried out among inpatients in …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 7–17 Read article
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Association of Vitamin D Binding Protein BP rs2282679 Gene Polymorphism and Serum Levels of Vitamin D in Patients with Vitiligo
Abstract: For vitamin D to have an impact, the vitamin D receptor (VDR) must be expressed and activated in the nucleus. The VDR has several known genetic variants. Biological impacts can be caused by changes in DNA sequences known as "polymorphisms" that are common in the population. Vitiligo is a disease that causes loss of skin color in patches, and it is a chronic (long-lasting) autoimmune disorder loss of color. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 45–52 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 41–55 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of AgroChemistry · Vol. 3, Issue 1, 2025 · pp. 35–49 Read article
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Engineering Anti-Tau Monoclonal Antibodies for Alzheimer’s Disease and Parkinsonian Tauopathies: A Biotechnological Perspective
Abstract: Neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease are characterized by progressive neuronal loss associated with abnormal protein aggregation. Among these, tauopathies are defined by the accumulation of hyperphosphorylated tau protein, which plays a central role in disease progression. Advances in biotechnology have enabled the development of anti-tau monoclonal antibodies (mAbs) as promising therapeutic agents aimed at neutralizing pathological tau species and inhibiting their propagation. This review provides a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Attitude of Undergraduate Agriculture Students Towards Farming: Empirical Evidence From a Premier State Agricultural University in India
Abstract: Agricultural education plays a critical role in developing skilled human resources for sustaining and revitalizing the farming sector in India. Despite agriculture being the backbone of the national economy, there is increasing concern about the declining inclination of educated youth towards farming as a profession. The present study was undertaken to assess the attitude of undergraduate agriculture students towards farming and to examine selected socio-demographic, educational, economic, and psychological factors …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 15, Issue 2, 2026 · pp. 41–56 Read article
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A Study to Assess Prevalence of Tobacco Use Among Adolescents and Assess the Effectiveness of Structured Teaching Program Regarding Ill Effects of Tobacco Use and Its Prevention Among Adolescents in Selected Community of New Delhi
Abstract: Tobacco use among adolescents has become a global challenge and it is reaching pandemic levels. The objectives of the study were (a) to assess the prevalence of tobacco use among adolescents in a selected community of New Delhi, (b) To provide an organised education programme on the negative effects of tobacco smoking and how to prevent it for teenagers in a chosen New Delhi community, (c) to determine whether the …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 23–38 Read article
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Comparative Study to Assess the Attitude of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counselling is a process that involves working with a professional to explore and understand various aspects of one's personality, skills, interests, values, and goals to make informed decisions about your career. Aim: The main aim of the study was to assess the attitude of higher secondary school students regarding career counselling in selected rural and urban schools of Kashmir. Methods: This study employed a descriptive research design using …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 11–18 Read article
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Nutritional Comparison of Plant-Based Dairy Alternatives vs. Cow's Milk
Abstract: The increasing popularity of plant-based dairy alternatives has sparked a closer look at how they compare to traditional cow’s milk, especially in terms of nutrition and health. Cow’s milk is usually regarded as a good source of high-quality protein, calcium, vitamins B12 and D, and other critical elements. Its complete protein and easily absorbed calcium make it particularly important for bone health. However, more people are turning to plant-based options …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–11 Read article
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Career Counselling and Personality Assessment App
Abstract: From the early foundations of career counselling, the role of self-awareness in making informed career choices has been well recognized. Frank Parsons, widely regarded as the pioneer of career counselling, emphasized the necessity of understanding oneself to make wise career decisions. He proposed that this self-awareness should be systematically connected to job requirements and opportunities through logical reasoning and structured analysis. This approach aims to empower individuals to make well-informed …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 2, 2025 · pp. 63–69 Read article
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The Study of Preference on Skill-Based Training Among Household Women in Gudalur Town
Abstract: This study explores the need for skill-based training among women in households in Gudalur town, identifying preferred training types, choice-influencing factors, and participation barriers. Skill development is a critical component of women's empowerment, promoting financial autonomy and social mobility. Surveys were conducted with 50 women, who were chosen using a stratified random sampling method. The survey comprised demographics, most preferred training courses, perceived benefits, and participation barriers. Descriptive statistics was …
Published in International Journal of Community Health Nursing And Practices · Vol. 3, Issue 2, 2025 Read article
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A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke
Abstract: Coronary Heart Disease (CHD) and Transient Ischemic Attack (TIA) are significant cardiovascular and cerebrovascular disorders that often share similar risk factors and underlying pathophysiological processes. CHD involves the narrowing or obstruction of the coronary arteries due to atherosclerosis, resulting in diminished blood flow to the heart. A transient ischemic attack (TIA), often called a "mini stroke," occurs when blood flow to the brain is briefly disrupted, usually due to a …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 Read article
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Using MCDM Methods in automotive industry- A Review
Abstract: In the automobile sector, choosing the best car necessitates weighing a number of factors, including cost, fuel economy, performance, safety, and environmental impact. In order to solve complicated situations that need the simultaneous evaluation of multiple conflicting aspects, Multi-Criteria Decision Making (MCDM) procedures are essential. Among the various MCDM approaches, the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and MOORA are widely recognized for their straightforward structure …
Published in Journal of Automobile Engineering and Applications · Vol. 13, Issue 1, 2026 · pp. 20–26 Read article
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Smart Iron Box with Automatic Cloth Detection and Heat Adjustment
Abstract: Ironing continues to be a lengthy and sometimes monotonous activity in domestic chores; especially among those with busy schedules who need to ensure efficiency and minimize risks of harming delicate fabrics. This document discusses the design and development of an intelligent ironing machine that performs ironing tasks using embedded computing and multi-sensor fabric identification. Unlike traditional irons that depend entirely on the manually chosen temperatures and user discretion, the developed …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 2, 2026 Read article
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Melanogenic Inhibitory Effects of Sesamum indicum Phytocompounds Towards CDK 2, c-KIT, and BRAF.
Abstract: Objective: Melanoma is thought to be the fifth most frequent cancer in the US population, despite cancer being the most common cause of death in the globe. BRAF, CDK2, and c-KIT proteins are regarded as potential therapeutic agents since mutations in these proteins are the primary cause of melanoma. For the investigation of their pharmacological properties and therapeutic activities against the target proteins, Sesamum indicum L. and its phytocompounds were …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Molecular Docking Evaluation of Cedrus deodara Secondary Metabolites as a Potent Anti-ovarian Cancer Agent
Abstract: Objective: According to the statistics for the year 2022 it was seen that cancer total cases is 14,61,427. After breast cancer, ovarian cancer is the second most frequent cancer among women. The estrogen receptor (PDB ID: 1X7E), progesterone receptor (PDB ID: 1A28), and Phosphoinositide 3-kinases (PDB ID: 4FJY) can be considered as target protein for ovarian cancer. The plant Cedrus deodara and its phytochemicals were chosen in this study to …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 77–93 Read article
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Matching Minutiae Fingerprint Q-Learning Approach for Detail Coordination: Identifiable Mark Point
Abstract: The use of fingerprints for high-precision recognition and identification of people is one of the most reliable biometric symbols because it is non-invasive. In this paper, we propose an innovative approach to detect details on low contrast resolution image quality of fingerprint images. Existing algorithms are not very susceptible to sound and image excellence due to the lack of level of intensity. We recommend a reliable route to find fingerprints …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 1–15 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Use of the Computer Statistics in Oncology
Abstract: Currently, the use of computer statistics and computer statistical modeling in oncology for obtaining an accurate diagnosis, determination of the choice of treatment method and its correction in the process of ongoing treatment, prediction of the outcome of the disease, and evaluation of the effectiveness of the chosen treatment tactics is a decisive factor. The use of computer statistics, based on an adapted scientific and statistical package of the SSP …
Published in Research & Reviews : Journal of Statistics Read article