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1363 articles for “Pre-clinical”
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A Critical Analysis and Evidence-Based Study on The Impact of Sensory Health Screenings and Its Risk Factors In the Prediction and Prevention of Organ Damages
Abstract: ABSTRACTSensory organs operate the senses of vision, hearing, touch, smell and taste. In order to assess the type, severity, and locations of aberrant feeling, sensory examination is utilised. If the patient complains of diminished sensation, a sensory system exam is required. The main aim is to find out the sensory changes/impairments and its risk factors predictions in prevention of organ damages and to study the role of clinical pharmacist/Doctor of …
Published in Research and Reviews: A Journal of Health Professions · Vol. 12, Issue 3, 2022 · pp. 46–62 Read article
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Evaluation of Intravenous Admixtures in Tertiary Care Teaching Hospital
Abstract: Intravenous medication continues to expand and there is an increase in number of medications administered to each patient. There are no specific studies to identify the incompatibilities that commonly occur in hospitalized patients while administering these intravenous admixtures. The main aim of the study was to assess the potential incompatibilities associated with intravenous admixtures in tertiary care teaching hospital. The data for the present study were collected by patient interview …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 6, Issue 2, 2015 · pp. 9–16 Read article
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Dystocia in Nellore Brown Ewe Due to Breech Presentation of Twin Lamb
Abstract: A Nellore Brown ewe in its first parity was presented to the clinic with a complaint of abdominal straining. Previous day it delivered a live male lamb. Abdominal palpation revealed presence of another lamb. Per vaginal examination revealed breech presentation of lamb. Both rear legs brought into birth canal and a dead female lamb removed with gentle traction. Prolonged dystocia may lead to death of lamb and economical losses, if …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 4, Issue 1, 2015 · pp. 14–16 Read article
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Seroprevalence with Clinical Manifestations and Laboratory Profiles of Scrub Typhus Infection in Patients Attending to a Tertiary Care Hospital in Kota, South-East Rajasthan, India
Abstract: Background: Scrub typhus, a zoonotic rickettsial illness, is caused by Orientia tsutsugamushi, an obligate intracellular Gram-negative bacterium. It is transmitted by the bite of larval (chiggers) trombiculid mites.Owing to frequent outbreaks witnessed in different parts of the country in the recent past, scrub typhus is being described as a re-emerging infectious disease in India. Overall mortality varies from 7 to 30%. Objectives: The objective of the present study was to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 1, 2020 · pp. 1–9 Read article
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Comparative Study of Dosimetry Methodology and Software Tools for Personalized Radionuclide Therapy
Abstract: Purpose: The aim of this review article is to collate the detailed insight of different dosimetry methodology and non-commercial /commercial dosimetry software tools, along with clinical study explored by specific authors, published in recent peer-review journals. The present work is segmented in three sections: i) Literature review of various dosimetry methodologies to evaluate absorbed dose in personalized radionuclide/ radiopharmaceutical therapy. ii) Technical as well as comparative information related to commercial …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–27 Read article
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Toxic Epidermal Necrolysis Induced by Diclofenac Sodium in a Dental Patient: A Case Report
Abstract: Diclofenac sodium is a widely prescribed non-steroidal anti-inflammatory drug in dental practice. Propionic acid derivatives and oxicams have been reported to be associated with erythema multiforme and Steven-Johnson syndrome. Here the authors present a rare case report of toxic epidermal necrolysis (TEN) induced by diclofenac sodium. The patient presented in dental clinic with toothache for which planned tooth extraction was done under antibiotic cover. Post extraction, patient was prescribed diclofenac …
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 1, 2013 · pp. 27–29 Read article
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Leukemia Presenting as Guillain-Barré Syndrome: A case Report
Abstract: This case report shows an extremely rare initial manifestation of Leukemia in which patient presents with GBS like clinical pattern. A young lady presents with few days’ history of ascending areflexic quadriparesis with cranial nerve and respiratory involvement. On investigation, she was detected to have Acute Leukemia as the underlying cause. Thus, this case highlights the importance of ruling out haematological malignancies in case of Atypical GBS. Keywords: Leukemia, Guillain-Barré …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 8, Issue 2, 2018 · pp. 27–29 Read article
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Machine Learning-Based Approach for Heart Disease Prediction
Abstract: Heart disease is a significant global health challenge, with early diagnosis and prediction being essential for reducing mortality rates. Machine Learning (ML), an efficiently developing field within Artificial Intelligence, provides innovative methods for analyzing complex clinical data to predict heart disease. This review examines the basic machine learning techniques, data, and metrics used in cardiovascular disease prediction. It explores the role of supervised learning, such as decision trees and logistic …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 2, 2025 · pp. 64–73 Read article
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Assessing the Efficacy of Carica Papaya Leaf Extract in Preventing Thrombocytopenia: A Review
Abstract: A clinical condition known as thrombocytopenia is characterized by a low platelet count (less than 150 × 103/μL) in the blood, which leads to an imbalance in hemostasis and can result in multiple deadly consequences. Although the exact causes are not always known, they always lead to death by interfering with the formation of platelets and encouraging their destruction. Research demonstrates that Carica papaya leaf has special medicinal and therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 25–33 Read article
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Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital
Abstract: Background: Endocrine disorders affecting the thyroid gland represent some of the most frequently encountered conditions globally, necessitating prolonged therapeutic intervention and vigilant clinical surveillance. The evaluation of Drug utilization patterns (DUE) serves an essential function in examining prescriptive behaviours and promoting appropriate pharmaceutical management. Objective: To evaluate drug utilization patterns, prescribing trends, and rationality of therapy in patients with hypothyroidism and hyperthyroidism. Methods: A prospective, cross-sectional observational investigation was performed …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 1–5 Read article
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Management of Peroneal Nerve Paralysis in a Rottweiler Pup
Abstract: AbstractA six-month-old male Rottweiler pup presented to the clinics was diagnosed to have peroneal nerve paralysis. Physical examination, radiography revealed the presence of hock and hip abnormality and decided to manage the condition medically with supportive bandaging techniques. The pup was able to walk normally after a treatment period of one month and no complications were recorded further. The symptomology and treatment methods were discussed. Keywords: Peroneal nerve paralysis, hip …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 6, Issue 1, 2017 · pp. 17–19 Read article
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A Preceptor Based Research Study and Report on Analysis of Doctor of Pharmacy/Clinical Pharmacy Services Duringclerkship and Internshipward Round Postings in Hospital
Abstract: Clinical pharmacy is the branch of Pharmacy which is concerned with the science and practice of Rational Medication Use. Clerkship and Internship ward rounds refers to the Practice of Clinical Pharmacy Practice principles by Pharm.D (Doctor of Pharmacy) students. Aim: The Aim of the present study is the preceptor based analysis and report of Doctor of Pharmacy /Clinical Pharmacy Services during the Clerkship and Internship Postings at ESI Hospital, Indiranagar, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 19–31 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Clinical Profile of Dengue Fever with Its Acute Complications in Rural Population of Jaipur District
Abstract: Dengue is the most important mosquito-borne viral infection in terms of morbidity and mortality. In recent years, it has become a major public health concern. The present study was conducted on hospitalized adult patients of NIMS Medical College & Hospital with the aim to study the clinical profile and usual presentations of dengue fever. During the study of 75 patients of dengue infection, 18 had dengue fever (DF), 19 had …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 12–23 Read article
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Virtual and Augmented Reality in Medical Training Program: A Review
Abstract: PC created reality (VR) and created reality (AR) are two contemporary reenactment models that are right presently overhauling social insurance getting ready. VR gives a 3D and dynamic perspective on structures and the restriction of the client to converse with them. The consistent mechanical advances in haptics, show structures, and improvement exposure license the client to have a rational and insightful experience, drawing in VR to be perfect for arranging …
Published in Recent Trends in Parallel Computing · Vol. 8, Issue 2, 2021 · pp. 27–30 Read article
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Machine Learning Approach to Detect and Analyze Attention-Deficit/Hyperactivity Disorder
Abstract: Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by difficulties with attention, impulse control, behavioral regulation, and daily functioning that persist across childhood and adulthood. Clinical diagnosis is predominantly based on behavioral assessments and expert interpretation, which may result in subjectivity and delayed clinical decisions. To reduce reliance on subjective evaluation, this study introduces an automated ADHD identification framework that integrates resting-state functional Magnetic Resonance Imaging (rs-fMRI) with advanced machine …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 2, 2026 · pp. 22–26 Read article
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Prevalence and Factors Associated with Aggressive Behavior among Patients with Schizophrenia at Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia: a Cross-Sectional Study Design
Abstract: Introduction: Mental illness and aggression are often seen as inextricably linked. There is a growing body of evidence on aggressive behavior towards others by people with schizophrenia. Therefore, this study was designed to determine the prevalence of aggressive behavior and associated factors among people with schizophrenia. Method: Institutional based cross-sectional study was conducted during 6–31 May 2019 at the Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia. A total of 423 participants …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 9, Issue 3, 2019 · pp. 1–10 Read article
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Machine Learning Based Automated Detection of Sepsis: A Study
Abstract: Sepsis is a serious condition that occurs when the body's response to infection leads to tissue damage, organ failure, or death. Human body generally releases chemicals into the blood vessels to fight any kind of infection. Approximately 30 million people suffer from sepsis and 6 million people die from sepsis every year according to WHO. Around 4 million 200 thousand new-born and children are affected by sepsis all over the …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 10, Issue 1, 2023 · pp. 1–10 Read article
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Overview of Recent Advancement of Nano Stent in Pharmaceutical Application
Abstract: Interventional cardiology has witnessed remarkable progress with the evolution of nanotechnology, leading to the development of nanostents. Nanostents, characterized by their nanoscale features and innovative materials, have emerged as a cutting-edge solution for addressing the limitations associated with traditional stent technologies. This thorough analysis examines the most recent developments in the design, manufacture, and use of nanostents, emphasizing how they may completely transform vascular interventions. The first section of the …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article
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Prevalence of Malaria and the Associated Risk Factors among Pregnant Women Attending Antenatal Care in Health Institutions of Damot Woyide District, Wolaita Zone, South Nation Nationalities People Region, Ethiopia, (A Cross-sectional Study)
Abstract: Malaria during pregnancy is a major public health problem in Sub-Saharan African countries such as Ethiopia. The infection is a cause of morbidly and mortality in pregnant women and their fetuses eventually the newborns and infants. Hence, this study was conducted to determine the prevalence and risk factors of malaria among pregnant women that attend ANC clinic in health institutions found in Damote Woyide district, Southern Ethiopia. A health institution …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 3, 2018 · pp. 7–15 Read article