Search
314 articles for “toxic”
-
Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
-
Study the Impact of Corrosive Pollutants on Building Materials Corrosion
Abstract: Reinforced concrete structures (RCS) may be made more resistant to corrosion by using fiber reinforced polymers (FRP). One of the primary concerns with reinforced concrete constructions is corrosion. It causes disintegration in building material components by interactions with salts, acids, and alkalis. Both within and outside of reinforced properties, pollutants and effluents accelerate disbanding. When bio-waste and building materials come into contact, microorganisms and macro organisms, grow and emit acid …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 2, Issue 2, 2024 · pp. 20–29 Read article
-
A Futuristics Pyrolysis Technique: Conversion of Waste Plastic Polybags Into Fuel
Abstract: Plastics are high molecular weight materials composed of repeating polymer units and can be classified based on factors like chemical composition, structure, stiffness, application types, and processing methods. A key environmental issue with plastics is their non-biodegradability, causing them to persist in the environment. Pre-consumer plastic waste includes manufacturing defects, rejected items, and excess materials produced during virgin plastic manufacturing. In India, around 15,342 tons of plastic waste are collected …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
-
Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
-
Pharma Tech: Leveraging Software for Drug Development & Clinical Research
Abstract: The pharmaceutical sector is progressively adopting software solutions to enhance the drug development process and optimize clinical research results. Drug development is a time-consuming, expensive, and intricate process that traditionally requires extensive laboratory research, preclinical testing, and several stages of clinical trials. Software tools are revolutionizing these stages by improving efficiency, minimizing errors, and speeding up timelines. During preclinical testing, predictive software tools are used to model toxicological effects and …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 11–19 Read article
-
Exploring the Traditional and Modern Uses of Calotropis gigantea: A Review
Abstract: Calotropis gigantea, often known as C. gigantea or Sweta Arka, is indigenous to Bangladesh, India, and Thailand in South and Southeast Asia. It has therapeutic purposes. This plant features clusters of white or lavender waxy blossoms, an oval-shaped, light green leaf, and a milky stem. The beneficial properties of C. gigantea, which is commonly used in traditional medicine, especially in India, have been validated by recent scientific findings. Among their …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 · pp. 33–41 Read article
-
Green Chemistry Techniques used in The synthesis of Organic and Biochemical Compounds
Abstract: Green chemistry is closely related to “the design of chemical products and processes that specifically eliminate the use or generation of substances that are hazardous to humans, animals, plants, and the environment.” Green chemistry contains 12 principles that guide how a chemical is produced and used in a green and sustainable way, reducing pollution. Sustainable chemistry is a scientific concept that seeks to improve the efficiency with which natural resources …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 2, 2025 · pp. 01–9 Read article
-
Assay of the Antitrypanosomal Activity of Ziingiber Officinale Extract in Wister Rats
Abstract: This research investigated the antitrypanosomal effects of Zingiber officinale in rats infected with Trypanosoma brucei brucei. Twelve adult rats, 7 weeks old and of both sexes, were randomly divided into six groups (1 through 6), with each group consisting of two rats. All six groups (1–6) were intraperitoneally injected with 0.1 ml of blood containing 10⁶ Trypanosomes/ml. Groups 1–4 received daily intraperitoneal doses of the plant extract at concentrations of …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 32–37 Read article
-
Sustainable Innovations in Green Nanotechnology for Nanoparticle Synthesis
Abstract: Green nanotechnology is an emerging field that focuses on the environmentally friendly production of nanoparticles through biological and sustainable processes. This approach has diverse applications across industries such as pharmaceuticals, energy, electronics, and bioengineering. Compared to conventional methods, biologically driven nanoparticle synthesis, particularly utilizing green chemistry principles, offers a safer, eco- friendly, non-toxic, and cost-effective alternative. Metal nanoparticles are commonly synthesized through top-down and bottom-up strategies using physical, chemical, and …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
-
Assessment of Smoke Emission by Diesel Light Passenger Vehicles in Gwalior City, India
Abstract: The number of vehicles on the highways in Gwalior, a growing city in central India, has been increasing. Most of these vehicles run on diesel, which has led to higher pollution levels. The smoke from diesel vehicles has become a major problem, affecting both the air we breathe and people’s health. Emission’s control has become the major driving force in the development of diesel engines, because the use of conventional …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 1, 2025 · pp. 35–40 Read article
-
Eco-Friendly Synthesis of MgO Nanoparticles and Their Antibacterial Performance
Abstract: Nanoparticles (<100 nm in size) due to their enhanced surface area and high chemical reactivity have been a boon, ranging from micro to macro level. This has increased its applicability in various fields such as Food, textile, environment, biomedicine etc. Various metal oxides have been employed in Biomedical applications for their antibacterial, antioxidant and anticancerous activities. But MgO NPs have received much attention due to their high stability, non-toxicity and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 33–41 Read article
-
Comprehensive Review on Sterilization Methods and Material Considerations
Abstract: The problem of environmental contamination, which is important for both public health and the economy, has been addressed through a great deal of research on the sterilization and disinfection of pollutants and microorganisms. Many types of pollutants and hazardous materials, such as microorganisms and toxic gases, are discharged into the environment and can enter the human body through ingestion, adsorption, or inhalation. Numerous respiratory conditions, strokes, lung cancer, and heart …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 2, 2025 · pp. 25–32 Read article
-
Extraction Properties of Mangifera indica Seed Kernels: A Comprehensive Analysis of Their Industrial Potential
Abstract: Mango (Mangifera indica) is widely regarded as one of the world's finest fruits, with a rich nutritional profile, including fiber, riboflavin, carotene, and ascorbic acid. Among its lesser-known components, the mango seed kernel offers significant nutritional and industrial value. Mango kernels are composed of protein, fat, carbohydrates, crude fiber, and ash, and contain bioactive compounds such as polyphenols, phytosterols, and tocopherols. The fat extracted from mango seed kernels has shown …
Published in Journal of Petroleum Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 22–28 Read article
-
Harnessing Honeybee Venom For Cancer Treatment: A Natural Remedy In Oncology
Abstract: Honeybee venom (HBV) has harvested significant attention as a promising natural compound with therapeutic potential in cancer treatment. This review investigates deeply into the current scientific understanding of honeybee venom, focusing on its anticancer mechanisms, molecular interactions, and potential clinical applications. Honeybee venom comprises various bioactive components, including melittin, apamin, phospholipase A2, and other peptides, which exhibit a wide range of biological activities. Recent research has demonstrated its ability to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 10–14 Read article
-
Potential Risk and Benefits in Developing New Nanobot Technologies and Future Posibilities
Abstract: The development of new nanobot technologies has the potential to revolutionize various fields, including medicine, manufacturing, and environmental science. However, as with any emerging technology, there are potential risks and benefits associated with nanobots. This abstract explores the potential risks, including toxicity, unintended consequences, and environmental impact, as well as the potential benefits, such as targeted drug delivery, diagnostic imaging, and tissue engineering. We also discuss the future possibilities of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 87–93 Read article
-
Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
-
In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
-
Calotropis: A Comprehensive Review of Its Phytochemistry, Pharmacology, and Therapeutic Potential
Abstract: Calotropis gigantea is a genus in the family Apocynaceae that grows in tropical and semitropical climates. India is home to this plant’s distribution. In Hindi, it is referred to as sweta arka. It is well known for its medicinal and ethnobotanical values. Calotropis gigantea, in particular, has a history of use in the treatment of many health-related issues, including disorders of the respiratory system, inflammation, and skin infections. Calotropis gigantea …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 2, 2025 · pp. 6–20 Read article
-
A Brief Review on Perovskite Materials: Synthesis, Properties, and Applications
Abstract: Perovskite materials have emerged as a transformative class of compounds, capturing widespread interest due to their remarkable properties and diverse applications across various fields, including optoelectronics, catalysis, energy storage, and environmental technologies. The synthesis techniques, classification, and unique properties of perovskite materials are thoroughly examined in this paper, which highlights the materials' potential to completely transform a number of sectors. One of the standout features of perovskites is their highly …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 42–49 Read article
-
Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article