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669 articles for “modulation”
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Farmer’s Eye: A Sustainable Crop-Field Monitoring System
Abstract: This paper outlines the creation and implementation of an Internet of Things (IoT)-driven smart agriculture monitoring system. It aims to tackle major issues in agriculture, such as inefficient irrigation, excessive resource use, and a lack of real-time data. The system focuses on the Arduino Uno, which connects to a variety of sensors: soil moisture for measuring substrate conditions, DHT11 for monitoring ambient temperature and humidity, MQ135 for checking air quality, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 15, Issue 1, 2026 · pp. 19–27 Read article
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Applications of Koha in Maulana Azad Library, Aligarh Muslim University, and the Central Library and Knowledge Resource Centre, Teerthanker Mahaveer University, Moradabad: A Comparative Study
Abstract: The present study analyzes the use and application of the Koha open-source integrated library management system in two academic libraries: Maulana Azad Library, Aligarh Muslim University, Aligarh, and the Central Library and Knowledge Resource Centre, Teerthanker Mahaveer University, Moradabad. The study examines the level of implementation and effectiveness of major Koha modules from the perspectives of both library staff and users. A descriptive survey method was adopted, and data were …
Published in Journal of Advancements in Library Sciences · Vol. 13, Issue 1, 2026 · pp. 33–47 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Brain And Gesture Controlled Assistive System For Physically Challenged Individuals
Abstract: Assistive communication technologies are essential for improving the independence of individuals with physical and sensory disabilities. This paper presents the design and implementation of a multimodal assistive system that integrates brain signal acquisition and gesture recognition for real- time communication. The system utilizes an Electroencephalography (EEG) sensor to capture neural activity and a PAJ7620 gesture sensor along with an ADXL335 accelerometer to detect hand movements. The acquired signals are processed …
Published in Recent Trends in Sensor Research & Technology · Vol. 13, Issue 1, 2026 Read article
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Analysis of a Communication Link Performance Across Various Rayleigh Channels in Tropical Climates
Abstract: Tropical regions are characterized by intense and persistent rainfall throughout most of the year, and this environmental condition significantly influences wireless communication performance. The continuous presence of heavy precipitation weakens, scatters, and disrupts radio frequency signals, causing noticeable attenuation during transmission from the source to the destination. As a result, reliable communication becomes challenging, particularly for modern high-speed systems such as 5G networks. To address this limitation and enhance communication …
Published in Journal of Communication Engineering & Systems · Vol. 16, Issue 1, 2026 · pp. 06–12 Read article
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Molecular Dynamics and Therapeutic Architectures of Cannabinoid Receptors: A Comprehensive Review
Abstract: Expanding on these foundations, recent structural biology studies using cryo-electron microscopy have provided high-resolution insights into the conformational dynamics of CB₁ and CB₂ receptors. These findings have enabled a more precise understanding of ligand–receptor interactions, particularly how agonists, antagonists, and reverse agonists stabilize distinct receptor states. Such knowledge is critical for rational drug design, allowing researchers to selectively modulate downstream signaling pathways. For instance, CB₁ receptors primarily couple to Gi/o …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 36–40 Read article
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Polymer-Based Nanocomposite Coatings for Enhancing Solar Photovoltaic Panel Efficiency
Abstract: Environmental factors such as dust deposition, ultraviolet (UV) radiation, and surface reflection significantly reduce the performance of solar photovoltaic (PV) modules. This study investigates the development and performance evaluation of polymer-based nanocomposite coatings designed to improve the optical and surface properties of PV panel glass. A hybrid nanocomposite coating containing TiO₂ and SiO₂ nanoparticles dispersed in a polymethyl methacrylate (PMMA) matrix was synthesized using the sol–gel technique and deposited through …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 490–497 Read article
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Bonding Strength Characteristics of FRP Cylindrical Composites Under Hygrothermal Loading
Abstract: This study investigates the bonding strength characteristics and stress distribution patterns in fiber-reinforced polymer (FRP) cylindrical composites subjected to hygrothermal loading conditions. A four-phase cylindrical model incorporating AS-Graphite and S-Glass fibers with low modulus epoxy coating was analyzed under four distinct pressure loading conditions (25.984, 38.976, 77.953, and 155.906 MPa). Comprehensive stress analysis revealed significant variations in von-Mises stress, maximum principal stress, and minimum principal stress across fiber, coating, matrix, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 950–967 Read article
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Automatic Bluetooth Controlled Shutter System Using Microcontroller and Mobile Application
Abstract: Automation has become an essential part of modern engineering system. Manual shutter systems used in shops, garages, and industries require physical effort and time. To overcome these limitations, wireless control systems using Bluetooth technology have been developed. Bluetooth-based automation systems allow communication between smartphones and embedded systems. These systems are widely used due to their low cost, low power consumption, and ease of integration. This paper focuses on designing a …
Published in International Journal of Electronics Automation · Vol. 4, Issue 2, 2026 Read article
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Characterization of Mechanical and Viscoelastic Properties of Ceramic Nanoparticle-Reinforced Polymer Composites
Abstract: This study examines the mechanical and viscoelastic properties of polymer composites reinforced with ceramic nanoparticles, specifically focusing on enhancing the performance of the material through the incorporation of alumina nanoparticles. The composites were produced by embedding alumina nanoparticles into an epoxy matrix, and their properties were assessed using tensile, flexural, and dynamic mechanical analyses (DMA). The tensile tests showed a remarkable 40% increase in tensile strength and a 35% enhancement …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 71–82 Read article
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Analysis of Thermoelectric Generator for Automotive Exhaust Energy Recovery
Abstract: Utilizing waste heat from thermodynamic systems has shown to be a successful tactic for reducing environmental emissions and improving overall energy efficiency. About 40% of the chemical energy generated during fuel combustion is rejected by exhaust gases in internal combustion engines. It is possible to increase vehicle fuel efficiency and lower greenhouse gas emissions by harvesting this otherwise lost heat energy and turning it into useable electrical power. A viable …
Published in Trends in Mechanical Engineering & Technology · Vol. 16, Issue 2, 2026 Read article
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Substantial Enrichment of Mechanical, Thermal and Electrical Properties of Thermoplastic Polyester Elastomer by Melt Blending with Nano-ZnO
Abstract: Polymers are more reinforced with nano metal oxides, a completely flexible composite of engineering that simplifies the way of exhibiting good mechanical and chemical features. Polymer mixtures represent a very vital field in the handling of innovative ingredients, which have better features than net polymers. Polymer mixtures are able to deliver ingredients with prolonged useful features beyond the range that can be achieved from a single polymer equivalent. A methodical …
Published in Emerging Trends in Chemical Engineering Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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Evaluation of Modified Nanoparticles' Effects on Polypropylene Composites
Abstract: Numerous sectors use nanoparticles and nanocomposites in a range of applications, including medicine, textiles, cosmetics, agriculture, optics, food packaging, optoelectronics, semiconductors, aerospace, building materials, and catalysis. Polymeric nanocomposites, which combine organic polymers with inorganic nanoparticles, are a novel family of materials that perform better than their microparticle counterparts. They should therefore enhance the field of engineering applications. A polymer matrix's characteristics can be drastically changed by the addition of inorganic …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 2, 2023 · pp. 23–34 Read article
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Neural Network Based Fractional Order PID Controller for Harmonic Mitigation of Induction Motor Drive System
Abstract: Torque produced in IM (induction Motor) is collected fundamental torque, however, due to core saturation, air gap irregularity, and winding distribution; stator and rotor slotting harmonics torque are produced. This reduces the quality of the power system, life span, and performance of the motor and the controller device. In this paper, a neural network, based fractional order proportional integral derivative (NNFOPID) controller is designed to compensate the harmonics of the …
Published in International Journal of Electrical Power and Machine Systems · Vol. 1, Issue 1, 2023 · pp. 23–41 Read article
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Optimal Design and Fabrication of drone for agricultural Purpose
Abstract: Due to their reliable technology and simple operation, drones have found widespread use in many fields. This study aims to plan, investigate, and build a quadcopter for use in farming. This drone is implanted for pesticide spray in the farms. An innovative quadcopter design that is easily removable and transportable is used in this study. The entire structure is developed in Iron CAD, and the viability of the new design …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 81–92 Read article
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Hydrothermal modification of carbon fiber fabrics by ZnO nanorods for mechanical strengthening of CFRP laminates
Abstract: Hexagonal ZnO nanorods were produced on plain woven carbon fiber using a two-step seed-assisted hydrothermal procedure. By varying the process parameters such as molar concentrations, number of seeding cycles, and growth duration at a controlled growth temperature of 90 °C, it is feasible to produce ZnO nanostructures with a range of morphologies, including nanowires, hexagonal nanorods, and nanoflowers. The developed morphologies were examined using field emission scanning electron microscopy and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 127–139 Read article
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Implementation and Impact of RFID in Library Management Systems
Abstract: This system relies on UHF RFID scanners at the gate and transaction section, which are supported by antennas and RFID transceivers embedded in library cards. These devices allow information to be electronically stored and read/written using radio waves without the need for physical interaction. It does not require manual input and instantly sends information about books and library users to the library's management system. It has a record-keeping and search …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 20–25 Read article