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392 articles for “cancer”
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Butrin Tackles Retinoblastoma – A Clinical Hypothesis †
Abstract: Breach of association of legumain protein activities to the corresponding cellular components results in over-expression of legumain, and constitutes a key biomarker for a variety of life-taxing sicknesses like cancer, Alzheimer’s/Parkinson’s and acute kidney injury. To suppress the functions of legumain, it is hypothesized that a water soluble and edible biomolecule, namely, butrin (7, 3’, 4’-trihydroxy flavanone-7, 3’-diglucoside) may have the therapeutic potential owing to its special ability to bind …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 26–30 Read article
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DentiDetect: Dental Diagnosis Powered by Deep Learning
Abstract: Dental X-rays play a crucial role in modern dentistry, enabling dentists to detect cavities, bone loss, and other hidden dental issues that are not easily visible during a routine examination. X-rays offer a clear picture of teeth, bones, and nearby tissues, enabling early identification of issues. This helps create more efficient treatment strategies and improves patient outcomes. Three commonly used types of X-rays include bitewing, periapical, and panoramic. Bitewing X-rays …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 3, 2024 · pp. 21–26 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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Performance Analysis of Machine Learning Algorithms For Disease Prediction
Abstract: In this 21st century, where Digitization makes humans measure, record, analyze and to manipulate the huge amount of data as per the requirement, prediction of the decease based on Machine Learning models will be representing one of the good applications of the efficient data handling. An Automatic Decease Prediction system based on the symptoms would be the great boon for the medical practitioners. The Supervised Machine Learning models, such as …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 9–18 Read article
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Comparison of a Human Papillomavirus Test with the Hybrid Capture 2 and a Real-Time PCR Method for 18 High-Risk and Low-Risk Human Papillomavirus Infections in Women
Abstract: Squamous intraepithelial lesions (SILs), which are a kind of cancer, and HUMAN papillomavirus (HPV) viral load have frequently been investigated as a risk factor in findings that were in dispute. These studies made use of several HPV viral quantitation assays [including the commercially available hybrid capture 2 (HC2) assays], which vary in their capacity to consider variations in cervical cell collection, linear dynamic range of viral load quantitation, and identified …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 10–16 Read article
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Biomedical Applications of Green-Synthesized Cobalt Oxide Nanoparticles
Abstract: The biomedical potential of cobalt oxide nanoparticles (Co3O4 NPs) synthesized via green methods is gaining recognition due to their biocompatibility and multifunctionality. This article reviews the antibacterial and anticancer properties of Co3O4 NPs synthesized using Delonix regia leaf extract. Characterization techniques confirmed their nanoscale size and uniform morphology. The antibacterial assay against Escherichia coli revealed significant activity, attributed to enhanced permeability and interaction with bacterial membranes. These findings highlight the …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 1, 2025 · pp. 20–29 Read article
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Sustainable Advances in Oral Pathology: The Impact of Artificial Intelligence
Abstract: Oral cavity cancers constitute about 4% of all malignant neoplasms. More than 9,900 new cases are reported from the developed countries yearly, and the 5-year mortality rate is higher than 39%. In Europe, the highest rates occur in Hungary, Croatia, and other Central and Eastern European countries; high levels are also seen in India, Pakistan, and Bangladesh. The management of endosseous pathologies presents considerable challenges because they often exhibit no …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 1, 2025 · pp. 24–27 Read article
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Single-Cell Genomics and its Impact on Understanding Cellular Heterogeneity
Abstract: Single-cell genomics has transformed how we study the differences between individual cells, helping scientists uncover the detailed variety within tissues that traditional methods could not reveal. Traditional methods, such as RNA sequencing, average gene expression across many cells, thereby missing subtle yet important cellular variations. Single-cell technologies, such as single-cell RNA sequencing (scRNA-seq), DNA sequencing, and epigenomics, allow researchers to study individual cells in extraordinary detail like never before. This …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 1–5 Read article
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Cross-Domain Comparative Analysis of Microwave Imaging Systems for Medical Diagnostics and Industrial Testing
Abstract: Microwave imaging is gaining significant traction as a non-ionizing, low-cost, and portable alternative to conventional diagnostic and inspection modalities in both medical and industrial domains. Leveraging the dielectric contrast between healthy and anomalous tissues or materials, microwave imaging systems enable early-stage detection and characterization of pathological or structural anomalies. This review provides a detailed comparative analysis of microwave imaging systems tailored for three critical applications: breast cancer detection, brain stroke …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 2, 2025 · pp. 39–48 Read article
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Advances in Nanoformulations for Targeted Drug Delivery Systems
Abstract: The work examines modern nanoformulations used for enhancing targeted drug delivery systems that simultaneously produce better therapeutic effects with reduced adverse effects. The pharmaceutical industry achieved deliverable drug development progress through diverse nanocarrier innovation which encompasses liposomes and nanoparticles and dendrimers and micelles. Tissue and cell-based directed delivery becomes possible via this technology to enhance the management of neurological disorders and cancer diseases. The investigation analyzes different nanoformulations by reviewing …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Reinventing Drug Delivery Through Cutting-Edge Nanotechnology
Abstract: Nanotechnology has emerged as a revolutionary platform in the field of drug delivery, offering novel strategies for the precise, efficient, and controlled delivery of therapeutic agents. The integration of nanocarriers, such as liposomes, polymeric nanoparticles, dendrimers, micelles, and inorganic nanoparticles, has significantly enhanced drug solubility, stability, bioavailability, and targeted delivery to specific tissues or cells. Targeted drug delivery systems based on nanotechnology minimize off-target effects, reduce systemic toxicity, and improve …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 44–61 Read article
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
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Intelligent Brain Tumor Diagnosis with AI-Based Classification* * Harnessing Deep and Machine Learning for Tumor Identification
Abstract: Brain tumors have become a leading cause of cancer- related deaths, posing significant health risks to many patients. This urgent medical challenge calls for rapid, automated, and reliable techniques to detect brain tumors accurately. Timely and precise tumor identification is crucial for devising effective medical plans that have the potential to save lives and improve patient outcomes. By leveraging advanced image processing methods, healthcare professionals can enhance their diagnostic capabilities …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Synthesis and Characterization of pH-Sensitive Poly (N-isopropylacrylamide-co-acrylic Acid) Hydrogels for Controlled Release of Doxorubicin
Abstract: pH-responsive polymeric hydrogels have attracted significant attention as intelligent biomaterials for site-specific and controlled drug delivery in cancer therapy due to their ability to respond to the acidic tumor microenvironment. In the present study, poly (N-isopropylacrylamide-co-acrylic acid) [P(NIPAM-co-AAc)] hydrogels were synthesized via free radical copolymerization and systematically characterized to evaluate their suitability for controlled delivery of doxorubicin, a widely used chemotherapeutic agent. The copolymer hydrogels were prepared using N-isopropylacrylamide and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 449–458 Read article
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Biological Membranes: Structure, Function, and Their Roles in Disease Pathophysiology
Abstract: Biological membranes are important structures that control cellular work, signal transmission, transport, and communication. Dysfunction of membranes has been considered in the development of many diseases, such as cancer, neurodegenerative diseases, and infections, with the distortion of lipid composition, protein activity, and cellular connections involved in the pathogenesis of the disease. The damage on membrane can be caused by oxidative stress, genetic mutation, and environmental influence to disrupt cellular homeostasis. …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 38–46 Read article
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Innovations in Gene Therapy: Revolutionizing Treatment for Genetic Disorders and Diseases
Abstract: Gene therapy is a revolutionary intervention in the treatment of genetic diseases since it is an intervention that aims at the very source of diseases, through editing and modification of genes. More recent innovations in gene editing systems, such as CRISPR-Cas9, CRISPR-Cas12, and prime editing, have greatly increased the accuracy and effectiveness of gene therapies, enabling more specific therapies. The opportunities of personalized medicine are also extended by the creation …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Stem Cell Therapy: Advancements, Applications, and Future Prospects in Regenerative Medicine
Abstract: Stem cell therapy has come up as a revolutionary technique in regenerative medicine living up to the promise in treating numerous diseases and injuries. The latest discoveries made in the field of stem cell research such as the introduction of gene editing technology like CRISPR and the creation of the 3D bioprinting process have increased the accuracy and efficacy of stem cell-based therapies. Examples include cardiac regeneration and repair of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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A Review Article on Oroxylum indicum: A Versatile Medicinal Tree
Abstract: Oroxylum indicum, commonly known as the Indian trumpet tree or Shyonaka, is a medicinal plant belonging to the Bignoniaceae family. It is widely used in traditional medicine systems such as Ayurveda for treating various ailments including neurodegenerative diseases, cardiovascular conditions, arthritis, hepatitis, malignancies, diarrhea, fever, and jaundice. The plant's therapeutic properties are primarily attributed to its rich content of bioactive flavonoids, which exhibit notable anti-cancer, anti-inflammatory, and analgesic effects. Found …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 2, 2026 Read article
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Artificial intelligence-integrated nanobiotechnology for precision medicine, smart diagnostics, and sustainable environmental applications
Abstract: Background: Nanobiotechnology integrates nanoscale materials with biological systems, enabling breakthroughs in drug delivery, biosensing, and environmental monitoring. However, the complexity of biological interactions and the vast parameter space of nano‑bio interfaces limit conventional design. Artificial intelligence (AI) offers powerful tools for modelling, predicting, and optimising these systems. Objective: This review provides a systematic, STM‑compliant overview of AI‑integrated nanobiotechnology across three domains: precision medicine (AI‑optimised nanocarriers, personalised therapeutics), smart diagnostics (AI‑powered …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article