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213 articles for “AI in Pharma”
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Understanding : Vitiligo A Skin Conditions Beyond Color
Abstract: Patches of skin that have lost their pigmentation are the hallmark of vitiligo, a chronic skin disorder. The afflicted skin patches turn white and typically have strong edges. Additionally, the skin's hair may turn white. There may also be issues with the inside of the mouth and nose. The rate at which skin conditions cause color loss is uncertain. When the cells that make melanin cease to function or die, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 27–33 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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Infectious Diseases: Current Epidemiology, Pharmacotherapeutic Strategies, and Global Health Perspectives
Abstract: Infectious diseases are still a major health challenge in the world, and there is increased strain on the health systems of nations. This review examines the most important issues in the management of infectious diseases, such as the distribution and effect of infectious diseases across the world, pharmacotherapeutic approaches, and the functions of public health interventions. New threats such as antimicrobial resistance (AMR), the contribution of climate change, and the …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 10–18 Read article
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Molecular Docking Study: Targeting mycobacterium leprae ML2640 Protein Using Active Compounds from Coscinium fenestratum
Abstract: Objectives: Leprosy is an infectious disease in skin, peripheral nerve and mucosa of upper airway. Around 70% of this infection is caused by Mycobacterium leprae, which was discovered during1873. Multi drug therapy is used for the treatment, still multiple drug resistance and reactions has been reported among patients. Hence, this work focused on identifying bioactive compounds from Coscinium fenestratum that can target mycobacterium leprae ML2640 protein by in-silico approach. Method: …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 2, 2023 · pp. 21–33 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Rethinking Type-1 Diabetes Treatment: Emerging Medicines Based on AAT Therapy and C-peptide Preservation Therapy
Abstract: The increasing number of cases, especially in the younger age group, along with the lack of accessible clinical solutions, make Type-1 Diabetes (T1D) a growing global health concern. While gene therapy and transplantation approaches are promising avenues, their excessively high costs and logistical difficulties make them inaccessible to the majority and can impose a financial burden on those suffering from it, adding to the challenges already faced by these advanced …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 19–29 Read article
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Exploring Potential Phytochemicals for Myasthenia Gravis Treatment: A Molecular Docking and ADME Analysis Approach
Abstract: Objective: Muscle feebleness and exhaustion derived from a disruption in neuromuscular transference are hallmarks of the crippling autoimmune disease myasthenia gravis (MG). The drawbacks of the current MG therapy options are frequently partial efficacy and adverse effects. To investigate the potential of phytochemicals in MG control, in this work we integrated molecular docking with ADME (absorption, distribution, metabolism, and excretion) analysis using a computer method. We identified molecules exhibiting favorable …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 1–13 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Standard Manufacturing Procedure (SMP) of Jaharamohara Bhasma Prepared by two Methods
Abstract: Introduction: Jaharamohara (Serpentine) is an important drug of Ayurveda and Unani medicine. In the literature of Rasashastra it is classified under Sikta Varga (group of silica containing drugs). In classical texts, different Bhavana Dravya (levigating material) are advised for the preparation of Jaharamohara Bhasma which enhances its potency. However, no work has been done till date to standardize Jaharamohara Bhasma by two different methods. Aim: An attempt has been made …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 1–13 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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Organic Compounds as Anti-inflammatory Agents, Natural and Synthetic
Abstract: Inflammation diseases still threaten humanity everywhere. For which there is always a continuous demand for immediate medication, the so-called anti-inflammatory drug. Anti-inflammatory organic compounds are either of natural origin or synthetic. Many drugs represent the main constituent of plants. Turmeric, ginger, garlic, spinach, broccoli, ginseng, blueberries, clove, Aloe Vera and pineapple all are plants almost rich in anti-oxidant and flavonoids that reduce inflammation. Researchers still have spent decades of years …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 05–18 Read article
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Polymeric Ion-Exchange Complexes of Carbomer for Taste Masking and Enhanced Drug Bioavailability: A Physicochemical and In Vivo Study
Abstract: Famotidine (FAM) was recognized as a crystalline powder that varies in color from white to pale yellow and possesses an extremely bitter flavor. This study aimed to conceal the unpleasant flavor of FAM through employing unconventional ion-exchange resins sourced from Carbomer polymer Evaluation (Carbopol 974P). We used FTIR, DSC, and XRD to look at the drug-resin combination in its hard form to learn more about its physical and chemical properties. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 727–740 Read article
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From Humours to Metabolism: An Integrative Review of Obesity Management in Unani Medicine
Abstract: Unani Medicine, a traditional complementary and alternative medicine (CAM) system, adopts a holistic, temperament-based approach to disease prevention and management. In classical Unani literature, obesity is described as Simān-e-Mufriṭ, a pathological condition arising from humoral imbalance, particularly the predominance of phlegm (Balgham) and derangement of temperament (Su’-e-Mizāj), most commonly of a cold and moist nature. This condition is attributed to a sedentary lifestyle, weakened digestive and metabolic faculties, and excessive …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Acupuncture in Pain Management: A Neurophysiological and Clinical Perspective
Abstract: Acupuncture, a key component of traditional Chinese medicine, has gained widespread recognition as an alternative therapy for pain management. This practice involves the insertion of fine needles into specific points on the body to influence the flow of energy or "Qi" (pronounced "chee") and restore balance. Mechanistically, acupuncture is believed to modulate pain through neurophysiological pathways, including the release of endorphins, the activation of the body's natural analgesic systems, and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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REPEATED MOPs VS DUAL APPROACH IN ACCELERATED ORTHODONTICS
Abstract: In contemporary orthodontics, there is a pressing need to minimize treatment duration, which is often a concern for both orthodontic specialists and patients. Prolonged treatment periods not only pose logistical challenges but also increase the risks of various dental issues such as cavities, periodontal problems, chronic discomfort, and root resorption. Accelerated orthodontics has emerged as a promising solution to address these challenges. Numerous efforts have been undertaken to expedite orthodontic …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 16–21 Read article
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A Review on Ethnomedicinal Claims of Gloriosa Superba Linn. (Langali).
Abstract: Aim: Gloriosa superba Linn., is a procumbent herbaceous climber and different parts of G. superba, have wide diversity of uses especially in traditional system of medicine among local healers. The goal of the current review is to gather information on research updates and claims pertaining to ethno medicine and folklore that is currently accessible. Material and Methods: Information and data regarding reported ethno medicinal uses and folklore claims of the …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 14–23 Read article
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Necessity of “Cigarette Smoking De-Addiction Kiosks” at Ayush Health and Wellness Centers – An Overview
Abstract: Introduction and Socio-Demography: Cigarette is the most common form of smoked tobacco that is used globally. About 1.3 million deaths have been reported in India associated with tobacco use. India has implemented several tobacco controls measures, and as a part of that, de-addiction centers play an important role in treating addictions using various therapies. However, the discontinuation from taking de-addiction care from those allopathic centers is high due to higher …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 9–19 Read article