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169 articles for “formulation approaches”
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Design and Assessment of Fixed Dose Combination Containing Fenofibrate and Pravastatin Sodium in Tablet Formulation: A Bioinformatics Approach
Abstract: The aim of this is study is to formulate and evaluate fixed dose combination of Fenofibrate and Pravastatin sodium in tablet dosage for the treatment of Dyslipidemia. For the formulation and optimization of fenofibrate layer, two factor three level factorial design was used as experimental design for optimization with a minimum of nine run. All the nine trial (F1–F9) has been formulated according to the experimental design by wet granulation …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 1–20 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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Recent Advances in Delivering Strategies of Domperidone Challenges and Opportunities
Abstract: Domperidone (DMP), a potent gastroprokinetic and antiemetic drug, exhibits poor aqueous solubility and limited oral bioavailability. Therefore, to develop oral preparations with optimized oral bioavailability, the pharmacokinetic parameters of DMP need to be controlled. The present review aimed to discuss the physicochemical characteristics of DMP causing its unfavorable oral delivery, to explore the viable oral formulation approaches, and to propose some recent formulation approaches that can mitigate the above mentioned …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 13–24 Read article
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Formulation and Evaluation of Polyherbal Soap with Antibacterial and Dermatological Benefits: A Polymer Chemistry Approach
Abstract: This study investigates the formulation and evaluation of polyherbal soap composed of extracts from Vitex negundo, Azadirachta indica, and Curcuma longa. These plants possess significant antibacterial, dermatological, and skin-nourishing properties. The soap formulation follows a saponification process using coconut oil and sodium hydroxide as primary reactants, incorporating polymer chemistry principles in soap structuring and stability. Polymers such as polysaccharides and fatty acid chains contribute to the stability, viscosity, and foaming …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 158–164 Read article
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Power Estimation Approach for Artix 7 FPGA using Machine Learning Technique
Abstract: This paper presents the power estimation approach using a suitable machine learning technique. Artix7 FPGA has been chosen as the target FPGA (Field Programmable Gate Arrays) platform for understanding the methodology of power estimation. There are various approaches of power estimation for FPGAs that have been given in the literature viz. probabilistic, statistical, and LUT- based, etc. In the past few years, the demand for hand-handled devices like smartphones, tabs, …
Published in Research & Reviews: A Journal of Embedded System & Applications Read article
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Child Friendly Innovation: A New Era in Pediatrics Drug Delivery Systems
Abstract: Pediatric formulations are becoming more and more popular as a result of advancements in pharmaceutical delivery technology. For young patients, there isn't a safe and effective drug delivery system in place. Since children's pharmacokinetics and pathophysiologic profiles differ from those of adults, it is imperative to design and develop an innovative and appropriate delivery system to provide accurate and dependable medicine administration to pediatric patients. Discussions will be held under …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Tropical Medicine and Leishmaniasis: Unraveling the Complexities of a Neglected Tropical Disease
Abstract: Protozoan parasites of the genus Leishmania are the cause of the vector-borne disease leishmaniasis, which poses a serious threat to global public health in tropical and subtropical areas. Despite being common and having a significant effect on human health, leishmaniasis is still a neglected tropical disease, with little funding available for investigation and prevention. This article examines the relationship between leishmaniasis and tropical medicine, emphasizing the particular difficulties this intricate …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 2, 2024 · pp. 29–39 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Innovative strategies in capsule formulation from concept to market
Abstract: Innovative strategies in capsule formulation have revolutionized drug delivery and nutraceutical development, offering advanced solutions from initial concept to market release. This report explores the transformative techniques at each stage of capsule formulation, detailing novel approaches in ingredient selection, encapsulation technology, and manufacturing processes. By leveraging advancements in artificial intelligence, encapsulation methods, such as liposomal and nanoparticle technologies, and materials science, formulators can optimize the bioavailability, stability, and targeted delivery …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Advancements in Solubility Enhancement Through Liquisolid Compact Technology: A Comprehensive Review
Abstract: The study examines Liquisolid Compact Technology as an innovative approach for improving the bioavailability and solubility of drugs that are poorly soluble in water. Liquisolid systems, comprising solid carriers and liquid drugs, offer advantages such as improved drug release and bioavailability, reduced manufacturing costs, and controlled drug delivery. The technique involves dissolving or suspending the drug in non-volatile solvents, adding carrier materials, super disintegrants, and coating materials, and then compressing …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 25–34 Read article
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Solving Optimization Problems Using the Graphical Method of Linear Programming
Abstract: Linear programming is a mathematical optimization technique used for maximizing or minimizing a linear objective function while satisfying a set of linear constraints. This method plays a crucial role in various industries, including manufacturing, finance, transportation, and supply chain management. Among the different approaches to solving linear programming problems, the graphical method provides a simple and intuitive way to visualize and solve problems involving two decision variables. By plotting constraints …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 2, 2025 · pp. 01–08 Read article
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Review On: Liquid Crystal Cream for Topical Drug Delivery
Abstract: A Liquid crystal creams represent a novel approach in skincare formulations, leveraging the unique properties of liquid crystal technology to improve skin hydration and barrier function. An overview of current developments in liquid crystal cream formulations is given in this article, with an emphasis on the benefits they offer for skincare and their composition and structure. Liquid crystal creams mimic the lipid bilayers of the skin, offering enhanced compatibility and …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 1–8 Read article
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The Role of Gut Microbiota in the Health Effects of Fermented Dairy Products
Abstract: The human gut microbiota plays a crucial role in maintaining physiological health, influencing digestion, metabolism, immune function, and even mental well-being. Among dietary interventions aimed at modulating gut microbiota, fermented dairy products have emerged as particularly promising due to their rich content of live microorganisms, bioactive compounds, and nutrients. This review explores the intricate interactions between fermented dairy products and the gut microbiota, highlighting their potential health benefits and underlying …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 5–10 Read article
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AI-Driven Multi-Objective Optimization of Conductive Polymer Composites for High-Performance Flexible Electronics
Abstract: The development of conductive polymer composites (CPCs) is critical for advancing flexible and wearable electronic technologies. However, the conventional trial-and-error approach to material formulation is time-consuming and often inefficient due to the high-dimensional nature of the design space. This study introduces a novel AI-driven framework that integrates machine learning (ML) with multi-objective optimization to accelerate the discovery of high-performance CPCs. A dataset of 1,000 experimentally reported formulations was compiled, capturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 734–745 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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Utilization of Whey in Functional Dairy Beverages: Nutritional, Technological, and Industrial Perspectives
Abstract: The dairy industry plays a vital role in global nutrition and the economy, producing a wide range of products that contribute significantly to human health. Among its by-products, whey is generated in large quantities during cheese and paneer production and has traditionally been considered a waste material, posing environmental challenges due to its high biochemical oxygen demand. However, in recent years, whey has gained considerable attention as a valuable resource …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 15, Issue 1, 2026 · pp. 18–23 Read article
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Deep Reinforcement Learning-Based Intelligent Energy Management Strategy for Battery–Supercapacitor Hybrid Energy Storage Systems in Electric Vehicles
Abstract: As the number of EVs increases, smart solutions for energy management are needed that will optimize energy use, prolong battery life and boost vehicle performance. The application of conventional rule based and optimization-based Energy Management Strategies (EMS) for Battery–Supercapacitor Hybrid Energy Storage Systems (HESS) often leads to sub-optimal power management, supercapacitor mismatch and battery degradation when subjected to varying driving conditions. This study aims to design an intelligent energy management …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 2, 2026 Read article