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72 articles for “anti-bacterial activity”
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Chompound contaning oxadiazole derivatives and their potential therapeutic uses.
Abstract: Derivatives of oxadiazole or furadi azole rings constitute a significant class of heterocyclic substances. Oxadiazole is a heterocyclic, five-membered ring with two carbons, one oxygen atom, two nitrogen atoms, and two double bonds. They are produced by substituting two nitrogen (-N =) atoms for two methylene groups (= CH) in furan. The furan ring's aromaticity was significantly decreased by substituting these groups, resulting in a conjugated diene character. There were …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 68–74 Read article
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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Synthesis, Characterization, Biological evaluation, and in silico study of aniline derivatives
Abstract: In many hospitals worldwide, bacterial infections brought on by resistant strains are wreaking havoc, particularly in patients who are already impaired by age, disease, and other conditions. Due to the bacterial resistance, it is required to search for newer antibacterial drugs or molecules. In the current study, we aimed to develop aniline derivatives, followed by their anti-bacterial and in silico studies. Out of all the synthesized derivatives, compound 4d was …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 25–32 Read article
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Fabrics and medical devices (catheters) coated with Zn doped CuO nanoparticles kills micro-oganisms and provide healthy environment
Abstract: These days, drug resistance by microorganisms is a major challenge in the field of medicinal chemistry. Most of the familiar antibiotics turnout to be of no impact in curbing the proliferation of microorganism (bacteria, virus and fungus). To address the issue of multi-drug resistance (MDR) and extremely drug resistance (EDR) in microorganisms that cause various health complications, like the dental decay, biofilm formation, foul smell, delayed wound healing, aggravation of …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 1, 2025 · pp. 1–9 Read article
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Properties and antimicrobial activity of bacterial nanocellulose composite incorporated with silver nanoparticles based on green synthesis
Abstract: Green silver nanoparticles (AgNPs) synthesized using medical plant extracts as capping and reducing agents demonstrate broad applicability in addressing the threat posed by infections. In this study, we present a sustainable, low-toxicity, and cost-effective bacterial nanocellulose composite with silver nanoparticles based on green synthesis that uses Origanum vulgare as a reducing agent due to numerous biological components. The formation of AgNPs in composite and morphological properties was analyzed using scanning …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 323–328 Read article
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Synthesis and Characterization of Pyrazole Heterocyclic Derivatives via Vilsmeier-Haack-Reaction and its Schiff`s Bases.
Abstract: The synthesis of New Schiff bases (2; and 3a-c) is reported in this study. These bases were created by reacting -chloro-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde (1) with various amines that contained various pharmacophore atoms or groups, such as derivatives of benzothiazole and aniline, in the hopes of having antimicrobial and antifungal properties. Using mild reaction conditions and a good yield percentage, mono-pyrazole Schiff bases (2 and 3a–c) were designed and synthesized by reacting 5-chloro--3-methyl-1-phenyl-pyrazole-4-carbaldehyde …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 3, 2024 · pp. 34–48 Read article
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A review on antibacterial properties of eucalyptus oil and different eucalyptus species used in pharmaceuticals
Abstract: Medicinal plants with antimicrobial compounds play a crucial role in combating various pathogens. Eucalyptus, belonging to the myrtle family, is notable for its diverse antimicrobial compounds. This fast-growing plant thrives in many countries and its various parts offer significant medicinal value, including timber, pulpwood, and essential oils. The leaves, often considered forest harvesting waste, contain essential oils with potential medicinal benefits. Members of the genus Eucalyptus are highly valued for …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 10–19 Read article
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Flavonoid Contents and Antioxidant Activity of an Endophytic Bacteria Associated with Medicinal Plant Humulus lupulus
Abstract: Endophytes are symbiotic microorganisms, most often bacteria or fungi, that reside and multiply within plant tissues without inducing visible signs of disease or negatively affecting the host plant. Endophytic bacteria contribute to plant development by stimulating growth, strengthening defence mechanisms, enhancing tolerance to both abiotic and biotic stresses, and facilitating improved nutrient uptake. Endophytic bacteria serve as an important reservoir of bioactive compounds, notably antioxidant molecules, that play a crucial …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 1–6 Read article
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Study of the Antibacterial Activity of Artemisia Absinthium against E. coli bacteria Isolated from Urinary Tract Infections
Abstract: Twenty clinically diagnosed samples were collected using transport medium swabs from the operating room at Al-Amal Specialized Laboratory in Iraq between November 2025 and February 10, 2026. Antibiotic susceptibility testing was performed on the 20 Escherichia coli samples. The results showed a clear difference in the bacterial isolates' response to the tested antibiotics. Imipenem demonstrated the highest inhibition rate, reaching 24.55% (100%), compared to the other antibiotics used in the …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 2, 2026 · pp. 17–25 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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Green Synthesis of Cobalt Oxide Nanoparticles Using Delonix regia Leaf
Abstract: Green synthesis of nanoparticles offers a sustainable and eco-friendly alternative to conventional methods. This study explores the biosynthesis of cobalt oxide nanoparticles (Co3O4 NPs) using Delonix regia leaf extract as a reducing and stabilizing agent. The synthesized Co3O4 NPs were characterized by UV-visible spectroscopy, Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM), confirming their uniform spherical morphology with an average size of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 1, 2025 · pp. 30–38 Read article
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Antibacterial Activities of Medicinal Plant Leaves Extract Against Isolated Escherichia coli Bacteria from Different Water Sources
Abstract: Objective: Escherichia coli are the most common pathogenic bacteria to accountable for food and waterborne illness. Therefore, in this way the study was conducted to resolve the occurrence of E. coli bacteria from different water sources in around Tamil Nadu along with to determine their antibiotic resistance profiles. Methods: Water samples were analysed for the presence of E. coli bacteria using specific agar media Eosin Methylene Blue and McConkeys. Colony …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Rauwolfia Serpentina: A Comprehensive Phytochemical Study of Its Bioactive Metabolites
Abstract: Rauwolfia Serpentina is an important medicinal plant used in Ayurveda, Unani, and folk medicine system of medicine. This plant grew as a bush in company of other plants as an evergreen structure. It is commonly known as ‘Sarpaghanda’. in Ayurvedic and Unani medicine system. It is safe and effective for the treatment of snakebites and various types of disease like malaria, breast cancer, prostate cancer, high blood pressure, insomnia, epilepsy, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 25–50 Read article
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Synthesis, characterization, and antibacterial activity of silver nanoparticles with expired minocycline as reducing agent: proposed as a recycling technique
Abstract: In this research, expired minocycline, a broad-spectrum tetracycline antibiotic, was employed as both a reducing and stabilizing agent for the eco-friendly synthesis of silver nanoparticles. This sustainable method avoids the use of toxic chemical reducing agents, providing a greener alternative for nanoparticle production. The synthesized silver nanoparticles were analyzed using several characterization techniques, such as UV-Vis’s spectroscopy, scanning electron microscopy, transmission electron microscopy, and Edex analysis, to assess their structural, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 16, Issue 1, 2026 · pp. 30–43 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates
Abstract: Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Grampositive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 25–31 Read article
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Characterization and Antimicrobial Investigations of Isomeric Pr(III) Juglonates
Abstract: Hydroxy napthoquinone derivatives constitute an interesting group of ligands which is recognized as ‘Juglones’. Isomeric Lawsone-Juglone and Phthiocol-Plumbagin are the most important members of the Juglone series and are biologically active, having natural origin. They form isomeric pairs of ligands resulting into isomeric pairs of metal chelates. The isomerism is occurring due to formation of either five or six membered rings in the metal chelates. In the present work Prasodymium …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 545–552 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 41–55 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of AgroChemistry · Vol. 3, Issue 1, 2025 · pp. 35–49 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article