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43 articles for “adverse events”
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Enhancing Patient Safety in the Operating Room: Mitigating Adverse Events and Preventing Errors
Abstract: The safety of patients in the operating room is a matter of utmost importance for healthcare practitioners. Adverse events and errors during surgical procedures can have severe consequences for patients, leading to complications, prolonged hospital stays, and even mortality. This review article aims to provide a comprehensive analysis of strategies to enhance patient safety in the operating room, focusing on mitigating adverse events and preventing errors. Through a thorough examination …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 1, 2023 · pp. 1–5 Read article
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Adverse Events Associated with Oral First-in-Man Administration of New Chemical Entities Compared with Placebo – An Analysis of 14 Single- and Multi-Dosing, Double-Blind, Placebo-Controlled Studies
Abstract: This investigation is a retrospective analysis of the adverse events (AEs) associated with oral administration of new chemical entities (NCEs)for the first time in humans. We gathered data from 14 single- and multiple-dosings of FIM NCE studies conducted in our centre over a period of 5 years. In total, 452 subjects were dosed. A total of 2280 doses were administered. Active medication was given on 1763 dosing occasions and placebo …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 3, 2012 · pp. 1–6 Read article
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Study on Healthcare Workers in a Tertiary Institute of Uttarakhand on Possible Adverse Effects after COVID-19 Vaccination
Abstract: The occurrence of a devastating pandemic of severe acute respiratory syndrome coronavirus-2 (SARS- CoV-2) infection, which emerged in the year 2019 in Wuhan, China, has come out as a primary concern all over the world. Many measures were adopted to prevent its spread, but the role of vaccines is inevitable. Understanding the importance of vaccines in the current situation, Government of India launched the COVID-19 vaccine drive on Jan 16, …
Published in Research and Reviews : A Journal of Immunology · Vol. 13, Issue 1, 2023 · pp. 20–31 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Artificial Intelligence in Pharmacovigilance: Improving Drug Safety
Abstract: Artificial intelligence (AI) is revolutionizing pharmacovigilance (PV) by enhancing the detection, assessment, and prevention of adverse drug reactions (ADRs). This review examines how AI technologies – such as machine learning (ML), natural language processing (NLP), and big data analytics – tackle existing challenges in pharmacovigilance (PV), including issues like underreporting, large data volumes, and inefficiencies in data processing. AI improves drug safety by automating data collection, enabling real-time adverse event …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 1–16 Read article
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Adverse Drug Reactions and Pharmacovigilance of Herbal Medicines in India
Abstract: The use of ayurvedic medicines is popular in India and in recent times has become accepted in other countries. Associated with this increasing use, are growing concerns about the safety of ayurvedic medicines. This paper discusses in brief the ayurvedic concepts of adverse reactions to medicines, the need for pharmacovigilance of ayurvedic medicines, challenges in introducing pharmacovigilance in ayurveda and some recommendations to successfully implement these activities. Pharmacovigilance is the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 5, Issue 1, 2016 · pp. 10–13 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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A Research Study and Report on Impact of Clinical Pharmacy on Vaccine Safety, Vaccine Vigilance, ADR Assesment and Reporting Among Pediatrics During Active Immunization Schedules at ESI Hospital
Abstract: Vaccine is a biological preparation that improves immunity to a given vaccine-preventable disease (VPD). A vaccine typically contains a disease-causing microorganism, or portion of it, and is often made from either live-attenuated or inactivated (killed) forms of the microbe, its toxin or one of its surface proteins. Vaccines may be monovalent or polyvalent (multivalent).. The main Aim of the study is to explore the knowledge, attitudes and concerns with respect …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 2, 2021 · pp. 35–45 Read article
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Impact of Vaccine Awareness Campaigns on Pharmacovigilance Reporting and Public Safety Monitoring
Abstract: Vaccination programs have significantly contributed to the reduction of infectious diseases worldwide; however, their success is closely tied to public confidence and robust safety monitoring systems. Pharmacovigilance plays a critical role in identifying, assessing, and preventing adverse events following immunization (AEFI). In recent years, vaccine awareness campaigns have emerged as a pivotal strategy to improve public knowledge, reduce vaccine hesitancy, and enhance reporting of adverse drug reactions (ADRs). This review …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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Adrenaline Use for Anaphylaxis Management during COVID-19 Mass Vaccination Program in India
Abstract: On 16th January 2021, GOI launched the COVID-19 vaccination campaign. With the introduction of the COVID-19 vaccine for the first time, there are expectations and apprehensions among the vaccine beneficiaries especially regarding the Adverse Events Following Immunization (AEFI). Although, vaccines-related serious AEFI are rare, but if they happen, there is a need to manage it quickly and efficiently not only to prevent mortality and morbidity in the individual recipient but …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 1–4 Read article
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Clinical Efficacy of Laxadi Taila Janubasti in the Management of Janusandhigata Vata (Knee Osteoarthritis): A Case Report
Abstract: Background: Janusandhigata Vata, described under Sandhigata Vata in Ayurvedic classics, characterized by pain, swelling, crepitus, stiffness, and restricted movement of the knee joint. Clinically, it resembles Knee Osteoarthritis (OA), a common degenerative Musculoskeletal disorder affecting the quality of life of elderly individuals. Janubasti is a localized oleation therapy widely employed for managing degenerative knee disorders. Laxadi Taila possesses Vatahara, Balya, and Asthi-Sandhana properties that may help restore joint function and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Concept of Qillat-I-Darqiyat (Hypothyroidism) in Unani System of Medicine: A Systemic Review
Abstract: All types of sue-i-mizaj have their specific consequences and effects on every tissue of the human body. The clinical features of Sue-i-Mizaj Baridratab are nearly similar to that Hypothyroidism, which translated as Qillat-i-Darqiyyat in Unani system of medicine. Amongst all the endocrine disorders, Hypothyroidism is the most common and usually affects females. The lifetime risk of thyroid disorder in women is one in eight. In India 42 million people suffer …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2020 · pp. 21–28 Read article
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Viruddhahara Causality in Lifestyle Disorders
Abstract: One is able to be free from disease only by following congenial diet. One is not able to sustain life without diet even of if endowed with medicine and that is why the diet is told as the great medicament by physicians. In Virudhaahara concept of food –-food interactions, Ayurveda cautions about unhealthy food and to be vigilant to prevent diseases by following appropriate food regimens and combinations. These guidelines …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 2, 2021 · pp. 38–46 Read article
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Clinical Efficacy of Sharbat Toot Siyah in Waram-i-Halaq (Pharyngitis) NUM CODE-98
Abstract: Sharbat Toot Siyah is an Unani pharmacopeialformulation frequently used for the treatment of Waram-i Halaq (pharyngitis). The objective of this clinical study was to evaluate its safety and efficacy in treatment of pharyngitis. Waram-i Halaq is an inflammatory conditionof pharyngeal mucous membrane caused by viral, bacterial and fungal infections; pollutants and chemical irritants. It may be infectious or non-infectious in origin.Although these may at times overlap; Waram-i Halaq is mainly …
Published in Research and Reviews: A Journal of Health Professions · Vol. 12, Issue 1, 2022 · pp. 7–22 Read article
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Development of Covid-19 Vaccine: A Review
Abstract: The emergence in December 2019 of a novel coronavirus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had devastating consequences globally. This is the worst catastrophe suffered by mankind in recent history. In the face of this severe disaster, people all over the world are frightened of the prospect of facing an outbreak or an annual recurrence. Control measures such as the use of masks, physical distancing, testing of …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 2, 2021 · pp. 12–22 Read article
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Effect of Unani Pharmacopeial Formulation Damavi on Iron Profile in Cases of Anaemia
Abstract: Anaemia is decrease in red blood cells or haemoglobin in blood; its frequency is around 2.36 billion i.e. 33% in 2015. Important symptoms associated include paleness of skin, weakness, shortness of breath, poor ability to exercise, etc. Many Unani formulations are used for treating anaemia but in this study, Tab. Damavi was used to see its effect on iron profile. This study was carried out at Regional Research Institute of …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 9–15 Read article
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Assessment of Hematological Disorders in Patients Using Phenytoin With or Without Nutritional Supplements
Abstract: Phenytoin is the most prescribed drug in controlling the epileptic seizures for prolonged period and this can lead to life-threatening adverse events. This prospective study is aimed to find out the incidence of hematological disorders (HDs) in patients receiving Phenytoin. The authors have screened 100 patients receiving phenytoin for ≥ 6 months, of whom 35 were recruited as per the eligibility criteria and their hematological parameters were noted, 90% of …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 3, 2015 · pp. 1–5 Read article
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Negative Pressure Wound Therapy and Intermittent Irrigation with Systemic Antibiotic Suppression followed by One-stage Revision in Delayed Periprosthetic Hip Infection Cases: Reinfection Rate
Abstract: Background: Success rate of one-stage revision remains controversial in patients with delayed periprosthetic joint infection after primary cementless hip arthroplasty. We evaluated the reinfection-free efficacy of negative-pressure wound therapy (NPWT) and intermittent pulsatile irrigation (IPR) using chlorhexidine/povidone iodide combined with systemic antibiotic suppression (SAS) followed by one-stage exchange procedure with NPWT in those patients. Materials and Method: Reinfection rate was assessed in randomly selected forty-two cases (group A) with NPWT-IPR-SAS …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 2, 2022 · pp. 7–15 Read article