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66 articles for “Three-dimensional structure”
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Study of Effect of Shape, Size and Symmetry on Electronic States of Some Three-dimensional Structures in Mesoscopic Size Regime
Abstract: This study presents theoretical study of effect of size and symmetry of different shaped three-dimensional GaAs structures in mesoscopic size regime. The effective mass Schrӧdinger equation is used in various shapes and its solution are modified as a function of volume and aspect ratio of structures. The calculated energy eigenvalues for square prism, equilateral prism, regular tetrahedral, cylindrical and spherical are comparatively analyzed to observe the effect of shape, size …
Published in Research & Reviews : Journal of Physics · Vol. 8, Issue 1, 2019 · pp. 26–36 Read article
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Bioinformatics-based Characterization of Stress Tolerance Spermidine Synthase from Zea mays
Abstract: The response to sensing environmental stress by plants is very important and can be short term by the synthesis of some protecting molecules against stress or long term by expressing phenotypic plasticity with alteration of developmental programme. The ability to respond to abiotic stress represents the main constraint on maize production. The spermidine synthase genes (Zmspds1 and Zmspds2) in Zea mays genome were identified by the PCR amplification and expression …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 2, 2013 · pp. 26–33 Read article
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On the Optimisation of fundamental frequency to determine the Optimal Design of Bracing System for A Three Storey One Bay Two Dimensional Planar Structure
Abstract: Bracing systems are useful to improve the resistance of multi-storey buildings subjected to wind forces acting in lateral direction on the structure. The main focus of this paper is to find the optimal design of the bracing for a three storey one bay two dimensional planar structure. The eigen frequency of the structure is maximized to determine the relative density using a stress based criteria of each element for every …
Published in Journal of Experimental & Applied Mechanics · Vol. 9, Issue 3, 2018 · pp. 55–59 Read article
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In Silico Identification of Therapeutic Agents for Dengue Virus by Molecular Docking
Abstract: The dengue virus causes serious health issues and a loss of quality of life. Dengue poses a yearly threat to half of the world’s population. The drugs that are based on allopathy are expensive and also exhibit toxic effects on tissues and biological activities. It is also generally accepted that most pharmacologically active drugs, including those derived from medicinal plants, are isolated from natural sources. The present study is directed …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 01–14 Read article
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Electrical Performance of the Silicon Nanowire Double Gate FET
Abstract: Silicon nanowire (SiNW) metal-oxide-semiconductor field-effect transistor (MOSFET) is a promising candidate of future CMOS device for further scaling. As the cross-sectional dimensions of SiNW channel is very small, cross-sectional shapes should affect electrical characteristics of SiNW FETs. In this work, effects of cross-sectional shapes of gate stack formation on (i) properties of double gate of SiNW FET; (ii) carrier transport properties including on-current, effective carrier mobility and inversion charge density; …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 22, Issue 3, 2020 · pp. 5–11 Read article
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A Review on Protein Structure Prediction
Abstract: Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence. The prediction of folding and secondary and tertiary structure from its primary structure. Structure prediction is fundamentally different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by bioinformatics and theoretical chemistry. It is highly important in medicine and biotechnology. Every two years, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 2, 2016 · pp. 1–7 Read article
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Hydrogel as a Drug Delivery System
Abstract: Hydrogels are hydrophilic three-dimensional, polymeric networks system. Hydrogel are hydrophilic system and capable of absorbing large amounts of aqueous solvent. It behaves like a semisolid system and generally follow non-Newtonian property. Hydrogel provide easy application, good spreadibility, non-grease, non-staining properly etc. Moreover, hydrogels can be converted to variety of forms apart depending upon the requirement including Newtonian and non-Newtonian slabs, microparticles, nanoparticles, topical gel, films etc. Hydrogels are commonly used …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 33–39 Read article
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Recent Developments in Structural Genomics: Uncovering Cellular Functions
Abstract: Structural genomics has become a groundbreaking field for understanding cellular functions by revealing the three-dimensional structures of proteins and other biomolecules. This field combines advanced methods like X-ray crystallography, nuclear magnetic resonance spectroscopy, cryo-electron microscopy, and computational modeling to explore the molecular structure and behavior of cellular components. Recent advances have significantly accelerated the pace of structure determination, bolstered by high-throughput methods and artificial intelligence tools like AlphaFold. These developments …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 30–35 Read article
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Behaviour of an End Flatted Space Frame Connector: A Parametric Study
Abstract: Space structures contributed many structural applications within the last decades insteel industry with a remarkable acceptance. The popularity of three-dimensional structures has been growing steadily, but their present acceptance all over the world is truly phenomenal. Nowadays, space structures are willing used by architects and engineers for industrial buildings, sport halls, gymnasia, hangars etc. The large number of space frames built shows clearly that, through prefabrication and industrialization, these systems …
Published in Journal of Structural Engineering and Management · Vol. 3, Issue 2, 2016 · pp. 29–36 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Proteins: Structure, Functions, Sources, Types, Advantages and Biological Importance
Abstract: Proteins are essential biological macromolecules composed of amino acids linked by peptide bonds and folded into specific three-dimensional structures. Their structural organization is closely associated with their biological functions, including structural support, catalysis, transport, regulation, defense, movement and storage. This review summarizes the basic features of proteins, including amino-acid composition, levels of structural organization, classification, major biological functions and important dietary sources. It also discusses the relationship between amino-acid sequence, …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 2, 2026 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Electrospun Structures for Dairy and Food Packaging Applications
Abstract: Electrospinning is an electrostatic fiber fabrication technique, in which a nonwoven mat of long fibers can be assembled into a three-dimensional structure due to bending instability of the spinning jet. Owing to its versatile nature and potential for applications in diverse fields including food packaging has been gaining more interest. It is a flexible and easy tool for producing ultrathin sized by applying electrical force. In this process, altering the …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 6, Issue 1, 2017 · pp. 17–23 Read article
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Structural Analyses of SoxY and SoxZ Proteins from Epsilonproteobacterium Sulfurimonas denitrificans: A Structural Bioinformatics Approach
Abstract: Abstract:Molecular level participation of epsilonproteobacteria for the global sulfur oxidation phenomena is an essential zone to be indulged with. Epsilonproteobacteria aids in the microbial sulfur metabolism both at and beneath the seafloor. For the recycling of the inorganic sulfur compounds, microbial redox reactions are one of the responsible and most important reactions to maintain the environmental sulfur balance. These reactions are carried out by phylogenetically diverse sets of microorganisms. The …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 1, 2015 · pp. 35–44 Read article
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Biodegradable Polymers Properties and Applications
Abstract: Polymers that can degrade into biologically compatible components under physiologic conditions present a far more attractive alternative for the preparation of drug delivery systems. The use of biodegradable polymers precludes the need for retrieval at the conclusion of the dosing regimen, thereby avoiding the potential complications associated with the use of non-degradable systems. A wide variety of approaches are continuously being pursued in the quest for improved biodegradable drug delivery …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 57–72 Read article
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A Combined Molecular Docking Analysis of The Phytochemicals of Ginkgo biloba against The Parkin Protein Target (Autoinhibited Parkin Catalytic Domain)
Abstract: This study's goal is to evaluate the specific therapeutic targets for Parkinson's disease (PDB ID: 4BM9) using molecular docking simulation and ADME analysis against bilobalide, quercetin, ginkgolide B, and protocatechuic acid (3,4-Dihydroxybenzoic acid). The Protein Data Base was used to extract theprotein's three-dimensional structure, and the PubChem database was used to retrieve the ligands. Using Auto-Dock Tools-1.5.7, a molecular docking simulation of the compounds was carried out. Since none of …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 1, 2023 · pp. 1–9 Read article
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Concrete Compressive Stress-Induced Crack Analysis and the Main Causes of Concrete Cracks in Construction
Abstract: The findings of experimental investigations into the micromechanical behaviour of concrete under various loading scenarios are presented in this work. Concrete specimens with normal and high strengths were examined under uniaxial compression in constrained spaces. Injection of a low melting point alloy was done into the concrete specimens' pores and fissures. To preserve the load-induced stress microcracks and the pictures from the cross sections of the concrete specimens photographed by …
Published in Journal of Experimental & Applied Mechanics · Vol. 13, Issue 2, 2022 · pp. 11–15 Read article
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Ground Improvement Technique Using Recycled Geo-Cell
Abstract: Geo-Cells are three dimensional Structures Orthogonally Designed. These are made using Polymers, we have Experimented and Designed Geo-Cells using Recycled High Density Polypropylene (HDPE), to get a Cost Effective Result. These Geo-Cells are then installed under Weak and Soft Soil to create a Low Density Unpaved Road. These Roads help us continue the work of shifting the Blocks from the Manufacturing Site to the Storage Place with Minimum Losses. This …
Published in Journal of Remote Sensing & GIS · Vol. 13, Issue 1, 2022 · pp. 31–40 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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3D-QSAR Studies on Protein Phosphatase 2A Inhibitors as Anti-cancer Agents
Abstract: The tremendous efforts by researcher indicates that cantharidin, nor cantharidin and their analogues shows anti-cancer activity due to their inhibition of cancer cell lines such as HT29, SW480, MCF-7, A2780, H460, A431, DU145 and L1210. The anti-cancer activities of cantharidin, nor cantharidin and their analogues involve the inhibition of serine/threonine protein phosphatises (PPs) activity. In this study, three-dimensional quantitative structure activity relationship (3D-QSAR) like comparative molecular field analysis (CoMFA), and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 1–19 Read article