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130 articles for “Fab stability”
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Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates functional genomics from OAS (4B+ sequences)(5) and structural databases (SAbDab: 10K+ structures)(6) with machine learning models achieving R=0.97 for SAP prediction.(11) We dissect biophysical mechanisms, benchmark predictive tools (DeepSP, ESM2), and engineering strategies (YTE, FW mutations) that enhance Tm by 5-10°C …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Extraction, Stability, and Application of Natural Dye from Spathodea campanulata Flower: A Study on Shelf Life, Yield, and Fabric Dyeing Potential
Abstract: The growing demand for sustainable and eco-friendly alternatives to synthetic dyes has led to increased interest in natural dye sources. Spathodea campanulata, commonly known as the African Tulip Tree, is a potential source of natural dye due to its vibrant floral pigments. This study focuses on the extraction, yield, stability, and application of the dye obtained from Spathodea campanulata flowers. The dye was extracted using an aqueous method, and its …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 3, 2025 · pp. 8–15 Read article
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Innovative Polymer Nanocomposites: Bridging Sustainability and Advanced Material Performance
Abstract: This study examines the evolution of bio-based polymer nanocomposites using eco-friendly synthesis methods to improve mechanical, thermal, and barrier properties. It involves the combination of sustainable synthetic polymers with natural polymers in the presence of nanofillers in a green and compatible fashion to generate durable nanocomposites. Optimal alignment of nanofillers with the polymer matrices can be achieved using solvent casting, melt blending, and in-situ polymerization as fabrication methods. Consequently, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1671–1679 Read article
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Polymer Chemistry of Ion-Selective Membranes and Hydrogels for Clinical Sodium Sensing: Advances and Perspectives
Abstract: Accurate and timely monitoring of serum sodium levels is critical in diagnosing and managing hyponatremia, a common and potentially life-threatening electrolyte disorder. Recent advances in polymer chemistry have driven the development of ion-selective membranes and hydrogels tailored for clinical sodium sensing, bridging the gap between material science and biomedical diagnostics. This review critically examines the design and synthesis of polymeric materials—focusing on block copolymers, conductive polymers, and stimuli-responsive hydrogels—used to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 895–901 Read article
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Impact of Red Stone Dust and Polymer Fabric in Enhancing the Properties of Black Cotton Soil
Abstract: To enhance the mechanical properties of problematic black cotton soil, engineers are focusing on reinforcing the soil with geosynthetic materials. This attention is particularly directed towards improving the strength characteristics of black cotton soil, given its inherent challenges associated with volume changes and plasticity. In this comprehensive study, red stone dust waste is introduced in varying percentages ranging from 5% to 35% to stabilize the black cotton soil. The goal …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 35–43 Read article
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Innovative Thin Film Technologies for Energy and Environmental Applications
Abstract: This article explores recent advancements in thin film technologies, focusing on their applications in photocatalysis, energy storage, and gas sensing. It highlights the growth of zinc oxide (ZnO) films via thermal evaporation for photocatalytic dye degradation, achieving up to 99.6% efficiency at pH 2. The study also examines vanadium pentoxide (V2O5) as a promising cathode material for lithium-ion batteries, discussing its structural characteristics and challenges related to conductivity and stability. …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 3, 2024 · pp. 33–38 Read article
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Flame-Retardant Polymeric Materials: Recent Advances and Future Directions
Abstract: This review explores essential flame-retardant polymers that play a vital role in various industries such as electrical & electronics, automobile, manufacturing, and firefighting. This review also highlights the latest progress in the design and synthesis of flame-retardant polymers, highlighting novel approaches such as the incorporation of nanomaterials, bio-based flame retardants, and the use of intumescent systems. Recent advancements include high-throughput screening, computational design, bio-based and sustainable flame retardants, self-healing materials, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 125–132 Read article
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Graphene Based Electronic Skin for Wearable Health Monitoring and Human– review on Machine Interaction, Materials, Structures and AI Integration
Abstract: Graphene-based electronic skin (e-skin) has emerged as a transformative technology for next-generation wearable health monitoring and advanced human–machine interaction (HMI). Owing to its outstanding electrical conductivity, mechanical flexibility, atomic-scale thickness, and biocompatibility, graphene enables the fabrication of ultrathin, conformal, and multifunctional sensors capable of mimicking the sensory functions of natural human skin. Over the past decade, research in this domain has progressed rapidly across four interconnected fronts: material synthesis and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Comparative Analysis of 3D-Printed and Molded Shape-Stabilized Phase Change Composites
Abstract: Thermal energy storage (TES) has become essential for efficiently storing and utilizing thermal energy across applications like industrial heating, power plants, batteries, medical devices, food preservation, and aerospace technology. Because of their high energy density, affordability, and environmental friendliness, phase change materials, or PCMs, are employed extensively. However, challenges like poor thermal conductivity and leakage limit their performance. To address these issues, 3D printing has emerged as a powerful tool …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 184–192 Read article
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Electromagnetic and Dielectric Performance of Polymer–Ceramic Composite Substrates for Fractal-Based IoT-Antenna Fabrication
Abstract: Polymer–ceramic composite substrates play a crucial role in determining the electromagnetic performance, mechanical stability, and thermal reliability of radio-frequency devices. In this work, a polymer-based composite substrate is systematically investigated for its suitability in compact IoT and RFID antenna applications. A fractal-structured antenna is employed as a functional test platform to evaluate the dielectric behavior, impedance characteristics, and radiation efficiency of the composite substrate. Novelty of the proposed reader antenna …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1518–1534 Read article
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IoT-Connected Transparent Conductive Polymer–Silver Nano-wire Electrodes for Real-Time Performance Monitoring of Flexible Solar Panels
Abstract: Flexible photovoltaic technologies have emerged as promising energy harvesting solutions for wearable electronics, portable power systems, and Internet of Things (IoT)-enabled smart devices. However, the limited mechanical durability of conventional transparent conductive electrodes and the lack of integrated real-time monitoring restrict their long-term reliability. This study presents an IoT-connected transparent conductive polymer–silver nanowire (PEDOT:PSS–AgNW) hybrid electrode for flexible solar panels, combining high optoelectronic performance with continuous wireless performance monitoring. The …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Structure-Property-Process Relationships in BNNS-Modified PEEK Nanocomposites for High-Performance Applications
Abstract: This study reports the design and performance evaluation of boron nitride nanosheet (BNNS)-reinforced polyetheretherketone (PEEK) nanocomposites fabricated using melt compounding and high-temperature Fused Filament Fabrication (FFF). PEEK, a high-performance thermoplastic, was reinforced with BNNS at 0.5–5wt.% to enhance mechanical, thermal, and tribological functionalities for advanced engineering use. Composite filaments were extruded and printed using a modified Bambu Lab FFF printer. Mechanical testing revealed a peak tensile strength of 108 MPa …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 867–888 Read article
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Polymer Matrix Characterization and Interfacial Engineering in Bamboo/Sisal/Chopped Mat Hybrid Fiber Composites
Abstract: The present investigation focuses on the characterization of polymer matrices and the interfacial behavior of bamboo, sisal, and chopped strand mat (CSM) fiber-reinforced epoxy composites. The work aims to understand how natural fibers influence the curing, thermal, and adhesion properties of hybrid composite systems. Experimental analyses were carried out using differential scanning calorimetry (DSC), dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), and Fourier transform infrared spectroscopy (FTIR) to evaluate curing …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 123–135 Read article
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High-Performance Polymer Composite Membranes for Selective Ion Transport in Advanced Energy Conversion Systems
Abstract: The development of high-performance Polymer Composite Membranes (PCM) with enhanced ion transport is essential for Polymer Electrolyte Membrane Fuel Cells (PEMFC). However, low-humidity conditions and filter agglomeration still limit long-term membrane stability. This research designs a functionalized PCM integrating cross-linked Poly (Vinyl Alcohol)/Poly (Ethylene Glycol) (PVA/PEG) matrix with sulfonic acid functional groups and Titanium Dioxide (TiO₂) nanofillers to improve selective ion transport under low-humidity conditions. Two types of PCM were …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 724–736 Read article
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Machine Learning Framework for Optimizing Polymer–Metal Oxide Composites as Charge Selective Layers in Perovskite Solar Cells
Abstract: To achieve high-performance and stability of perovskite solar cells (PSCs), it was important to incorporate innovative interfacial materials to tune the balanced charge extraction, low recombination, and enhanced operational lifespan. On this note, polymer composites with metal oxides have been proposed as promising candidates as charge selective layers (CSLs), whereby they present a rare combination of tunable energy levels, improved film forming abilities, and better interface engineering capabilities. In this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1073–1098 Read article
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Fabrication and Assessment of Tribological Performance of Nickel-Graphene-MXene Hybrid Nano-composites
Abstract: As industries such as aerospace, automotive, defence, and electronics demand materials with superior wear resistance, high strength, and thermal stability, traditional metals are reaching their performance limits. Hybrid nanocomposites offer a pathway to meet these stringent requirements. In this study, novel Nickel-Graphene-MXene hybrid nanocomposites were fabricated using a powder metallurgy route, incorporating varying weight percentages (up to 2 wt.%) of MXene and 1 wt.% graphene nanosheets into a nickel matrix …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 780–798 Read article
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Optimization of Direct Ink Writing Process Parameters for Liquid Silicone Rubber/TiO2 Composite Ink
Abstract: The purpose of this research is to develop and optimize the Liquid Silicone Rubber (LSR)/Titanium Dioxide (TiO₂) composite inks in Direct Ink Writing (DIW)-based 3D printing systems. The primary research objective was to use enhancement of mechanical, rheological, and dielectric characteristics of LSR using TiO₂ reinforcement but still retain extrusion stability and dimensional consistency. TiO₂ content (0, 5, 10, and 15 wt%) and catalyst and glycerol ratios were regulated and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 240–259 Read article
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Comparative Assessment of Polymers and Composites for Solar Panels: Fundamentals, Performance Metrics, Manufacturing, and Sustainability
Abstract: This paper presents a comprehensive review of the main types of Photo Voltaic polymers and composites such as crystalline silicon (both mono- and poly-Si), thin-film tech (CdTe, CIGS, a-Si), perovskites, and organic/dye-sensitized cells and analyses the parameters such as efficiency, fill factor, open-circuit voltage, temperature response, and degradation. The analysis focusses on polymers and composites and manufacturing techniques like vapor deposition, roll-to-roll printing, and both solution and vapor techniques for …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 120–130 Read article
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Thin Film Solar Cells: Progress in Materials, Fabrication, and Efficiency Enhancements
Abstract: Thin film solar cells (TFSCs) have drawn a lot of interest because of their potential for efficient and reasonably priced photovoltaic energy conversion. Their flexibility, low weight, and lower material consumption make them a desirable substitute for conventional solar cells made of crystalline silicon. This review explores recent advancements in TFSC technology, with a focus on materials, fabrication techniques, and efficiency improvements.Various thin-film materials, such as amorphous silicon (a-Si), perovskite, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 37–42 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article