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39 articles for “Diabetic nephropathy”
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Challenges in Diabetes Management Barriers and Support Systems in North India
Abstract: Background: The prevalence of Diabetes mellitus is ever growing in India and management of the disease is hindered by socio-economic, healthcare, and psychosocial barriers. Insofar as economic and social barriers pose challenges ranging from limited access to medical care, social stigma, specialist support leading to improper glycemic control, which is a strong predictor for diabetes complications, morbidity and mortality. Moreover, developing an understanding of systemic challenges and available supports is …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Emerging Therapies for Diabetes Mellitus: Efficacy and Safety of USFDA-Approved Drugs and Late-Stage Clinical Trials
Abstract: This review provides a comprehensive analysis of drugs approved by the U.S. Food and Drug Administration (USFDA) for managing diabetes mellitus (DM) from 2013 to 2022, including emerging treatments from phase 3 clinical trials during this period. Over the past decade, the treatment landscape for diabetes has evolved significantly, with new therapies not only improving blood sugar control but also targeting broader health outcomes like heart and kidney health. In …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 11–23 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Lifestyle Factors and Perceptions of Diabetes Among Individuals in North India
Abstract: Background: Diabetes mellitus is influenced by a complex interplay of genetic, environmental, and lifestyle factors. In North India, unique socio-cultural and dietary patterns shape individual behaviors and perceptions toward diabetes. Understanding these lifestyle choices and cultural beliefs is critical for designing interventions that improve adherence to medical treatment and promote healthier outcomes. Methods: A cross-sectional survey was conducted among 1,500 individuals diagnosed with diabetes across selected urban and rural districts …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Diet Mate: A Personal Nutrition and Health Tracking App
Abstract: The rising prevalence of chronic health conditions, including obesity, diabetes, and hypertension, has become a significant global health challenge. These conditions are often linked to poor dietary habits, which makes diet management a critical component of disease prevention and management. Traditional dietary approaches, such as generic meal plans or standard consultations with nutritionists, often fail to address the unique and evolving needs of individuals, especially those with specific health concerns. …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Foxtail Millet (Setaria italica): A Detailed Review on Nutritional Value, Anti-Nutritive Value, Potential Health Benefits
Abstract: Millets are a diversified collection of small-seeded grasses that have been used as a primary source of grain for generations in various regions of Asia and Africa. Millets are a staple grain this is historically consumed in dry regions everywhere in the international. They are high in protein, fats, minerals, nutrients, and fiber.. Millets are highly nutritious grains rich in essential amino acids, minerals, and dietary fiber, offering health benefits …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 20–26 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Cell Membranes as Therapeutic Targets: Implications in Infectious and Metabolic Disorders
Abstract: This is a review of the crucial role played by cell membranes in health and disease with respect to their contribution to infectious and metabolic diseases. Dysfunction of membranes, such as membrane transporter changes and changes in lipid content, has been associated with a variety of diseases, including diabetes, cardiovascular disease, and cancer. The present therapeutic approaches are focused on attacking membrane constituents by disrupting the entry of pathogens or …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 47–53 Read article
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Breaking Barriers: How Telemedicine is Reshaping Access and Quality in Healthcare
Abstract: Thanks to advancements in telecommunications technology, telemedicine has become a disruptive force in the delivery of healthcare, bridging geographical and accessibility gaps. This article offers a thorough examination of the advantages, difficulties, and potential applications of telemedicine in healthcare. Telemedicine has a number of benefits, one of which is that it makes healthcare more accessible, especially for underprivileged groups living in rural or isolated places. Telemedicine makes it possible for …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 1–4 Read article
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Determining the Root Causes of Complications in Hemodialysis Maintenance Therapy
Abstract: As with peritoneal dialysis and kidney transplantation, hemodialysis has been considered one of the most effective therapies for the replacement of kidney function. While this helps to save patients with the disease by decreasing morbidity /mortality/ rates, this medication has some side effects. These may manifest during the dialysis process alongside the ongoing treatment. Avoiding these barriers becomes crucial for improving the patients’ prognosis in this context.We are going to …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 27–47 Read article
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Aquatic Ecosystems: A Review on Prospecting of Anticancer Molecules from Fungi & Other Microbes
Abstract: Marine biota; namely, actinomycetes, bacteria, fungi, microalgae, green algae, oceanic weeds, mangroves, and other extremophiles constitute about 90% of the oceanic biomass. The organisms are taxonomically diverse, biologically productive/active, and biochemically unique. These unique biochemiques may act as a great source for the discovery of new bioactive molecules, including anticancer drugs. The marines produce medicinally potent biochemicals; namely, sulfated saccharides, polyphenols, and, sterols. Only a few of these alkaloids have …
Published in International Journal of Fungi · Vol. 1, Issue 2, 2024 · pp. 1–22 Read article
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The Nutritional Value of Moringa Plant as a Superfood: A Comprehensive Review
Abstract: Moringa oleifera, commonly known as the "miracle tree," has garnered global attention for its rich nutritional profile and diverse medicinal properties. This review article comprehensively explores the nutritional composition and health benefits of Moringa, highlighting its potential as a superfood. The plant is rich in essential nutrients, including proteins, vitamins, minerals, and bioactive compounds, such as flavonoids and phenolic acids. These constituents contribute to its antioxidant, anti-inflammatory, antimicrobial, and anti-cancer …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Effectiveness of Spencer Technique of Mobilization on Adhesive Capsulitis: A Single Case Study
Abstract: Background: Frozen shoulder, or adhesive capsulitis, is a condition characterized by pain, restricted motion, and stiffness in the shoulder joint. This occurs due to inflammation and the thickening of the joint capsule. The Spencer technique, is a manual therapy method consisting of seven steps designed to improve shoulder function by enhancing joint mobility, circulation, and lymphatic flow. These movements target shoulder extension, flexion, circumduction, abduction, and adduction, to reduce stiffness …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 14–20 Read article