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541 articles for “Computational methods”
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A New Computational Method for Dust and Gas Dynamics in Protoplanetary Discs
Abstract: The simultaneous evolution of dust and gas in protoplanetary discs regulates essential events in planet formation, such as dust accumulation, migration, and the initiation of gravitational instabilities. Nevertheless, precisely modelling this interaction continues to provide a significant computing problem owing to the extensive variety of spatial and temporal scales involved. In this study, we introduce an innovative computational framework for simulating dust-gas dynamics in protoplanetary discs, integrating a two-fluid hydrodynamical …
Published in International Journal of Universe · Vol. 1, Issue 2, 2025 · pp. 35–46 Read article
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Anti Covid-19 Drugs Suggested by Computational Methods: A Review
Abstract: Background and aims: Long COVID refers to the persistence of illness in individuals who have survived from COVID-19 infection. This article reviews long covid and the use of in silico techniques in drug development for COVID-19. Results: Many COVID-19 survivors have long COVID, which has become a burden in daily life. Various attempts have been undertaken to relieve symptoms and manage it, but there is no cure as of yet. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 16–34 Read article
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Effect of Welding Factors on Nugget Size of Polymer-Metal Composite Sheets Using Computational Methods
Abstract: Resistance spot welding (RSW) is a vital technique for joining materials in industries like automotive and aerospace. This study extends the application of RSW to polymer-metal composite sheets by developing 2D axisymmetric, thermo-electro-mechanical coupled model in ANSYS. The focus is on analyzing the temperature distribution, nugget formation, and parameter optimization in hybrid composite sheets, emphasizing the unique challenges posed by polymers' thermal and electrical properties. These properties differ significantly from …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 612–623 Read article
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A Review of Computational Methods for Image Restoration and Noise Reduction Using Reference Images
Abstract: Digital imaging systems play a vital role in numerous application domains, including consumer photography, biomedical imaging, remote sensing, aerial surveillance, and astronomical observation. Despite continuous advancements in imaging hardware and software, the visual data acquired by these systems often suffer from degradation caused by spatially non-uniform blur. This blur may arise due to several factors, such as lens imperfections, atmospheric turbulence, sensor limitations, motion between the camera and the scene, …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 13, Issue 1, 2026 · pp. 23–30 Read article
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Computational Approaches to Understanding Cellular Signaling Pathways
Abstract: Cellular signaling pathways are fundamental in regulating vital processes, such as cell growth, differentiation, and apoptosis. The intricate and interconnected nature of these signaling networks requires sophisticated methods for their analysis. Computational approaches, including mathematical modeling, network analysis, and machine learning, have revolutionized the way researchers analyze and simulate cellular signaling. This article provides a comprehensive overview of computational strategies employed to model signaling pathways, with a focus on integrating …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 8–13 Read article
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Integrated Optimization of Solar Photovoltaic Systems Using Taguchi Method and Computational Fluid Dynamics for Enhanced Efficiency
Abstract: The transition to renewable energy demands efficient and reliable photovoltaic (PV) systems to meet rising global energy needs. This study presents an integrated optimization framework combining the Taguchi method and Computational Fluid Dynamics (CFD) to improve the thermal and electrical performance of solar PV systems. A structured experimental design using an L9 orthogonal array evaluates the influence of three key parameters—material type, panel thickness, and cooling mechanism—on system efficiency. Analysis …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 3, 2025 · pp. 10–25 Read article
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A Critical Review of Generative Design Methods in Computer-Aided Drafting
Abstract: In the realm of Computer-Aided Drafting (CAD), generative design methods have become a potential strategy for automating and enhancing the design process. These methods generate a wide range of design possibilities based on given characteristics and limitations by using algorithms and computational tools. The objective of this critical study is to assess the benefits, drawbacks, and implications of generative design techniques in CAD. A notable result of this merger is …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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An approach of Computer Vision Methods for Driver’s Drowsiness and Yawn Detection
Abstract: Numerous studies have demonstrated that 4,444 traffic crashes are primarily caused by driver drowsiness. Due to advancements in digital computer systems, tiredness behaviour may now be studied by researchers worldwide. The goal of this project is to increase road safety by preventing accidents caused by sleepy drivers. To view the driver's face, use real-time facial recognition technology. A driver's attentiveness and reaction time may be impacted by weariness, which raises …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 21–26 Read article
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Genetic Variability and Statistical Methods: Key Insights for Computational Genetics Research
Abstract: Genetic variability, defined as the differences in DNA sequences among individuals, serves as the foundation of evolutionary biology and plays a pivotal role in species’ adaptability, resilience, and overall survival. Advances in genomic technologies, particularly high-throughput sequencing, have enabled unprecedented exploration of genetic diversity, fostering the growth of computational genetics. This interdisciplinary field combines statistical methods and computational tools to analyze genetic data, identify patterns, and link phenotypes to genotypes. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 19–23 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Modern Computer-aided Drug Design Methods: A Review
Abstract: Computer-aided drug design (CADD) has emerged as a crucial tool in the drug discovery process, offering a time-efficient and cost-effective approach to identifying potential drug candidates. This review aims to provide an overview of modern CADD methods, including high-throughput screening (HTS), structure-based drug design (SBDD), ligand-based drug design (LBDD), structure-based virtual screening (SBVS), and ligand-based virtual screening (LBVS). We discuss the basic principles, applicability, and limitations of each method, highlighting …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 14–20 Read article
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A Comprehensive Survey of Polymer Detection Techniques and Computer-Based Analysis Methods for Advanced Material Characterization
Abstract: Polymers are widely used in aerospace, automotive, biomedical, packaging, electronics, and manufacturing industries because of their lightweight nature, durability, and versatility. Accurate polymer identification and characterization are essential for quality control, recycling, performance assessment, and the development of advanced materials. Characterization helps determine important properties such as chemical composition, molecular structure, thermal stability, mechanical strength, and surface morphology, which influence material performance and application suitability. Traditional polymer detection methods include …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 921–929 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Role of Quantum Chemistry in Catalysis: A Comprehensive Review
Abstract: Catalysis plays a crucial role in modern chemical manufacturing, energy conversion, and environmental protection by enabling chemical reactions to occur more rapidly, selectively, and with reduced energy consumption. A fundamental understanding of catalytic processes at the atomic and electronic levels is essential for the rational design and optimization of catalysts. Quantum chemistry has emerged as a powerful theoretical and computational framework that enables detailed investigation of electronic structure, reaction energetics, …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 1, 2026 · pp. 01–16 Read article
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Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design
Abstract: The integration of bioinformatic tools with computational methods has revolutionized the field of Computer-aided Drug Design (CADD), enabling researchers to expedite the discovery and optimization of new therapeutics. This review provides an in-depth analysis of the bioinformatic tools utilized in CADD, encompassing molecular docking, molecular dynamics simulation, virtual screening, homology modelling, and molecular visualization. We go over the tenets, approaches, and uses of these instruments, emphasizing their value in expediting …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 1–10 Read article
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Advancements in Drug Design Technology and Its Impact on COVID-19 Treatment
Abstract: The deadly coronavirus disease 19 (COVID-19) pandemic has recently spread, raising concerns about global health. The search for novel therapeutic compounds is made more necessary by the persistent problem of the absence of licensed medications or vaccinations. By saving money and time, computer-aided drug design has sped up the process of finding and developing new drugs. The structured-based and ligand-based drug discovery subcategories of computer-aided drug design (CADD) are the …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 1–15 Read article
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Brain Tumor Detection Through CNN: Techniques, Dataset Insights, and Methodology
Abstract: Computer technologies are playing huge roles in some areas of the medical domain like surgery and therapy of different diseases. Researchers are doing studies and trying to experiment to detect different diseases like cancer, virus infections, and leprosy. There are many different medical imaging datasets that are publicly available for medical research purposes of diseases like cancer, virus infections, and leprosy, etc. where we can be able to access large …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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Unveiling Patterns in Complexity: The Role of Simple Statistics and Fuzzy Mathematics in Data Analysis
Abstract: In this study, statistical methods must be integrated with fuzzy mathematics to solve complex data. Statistical methods offer clear, unbiased, and computationally feasible tools for analysing numerical data. whereas fuzzy mathematics excels in describing the vagueness and ambiguity of human feeling by way of linguistic variables, membership functions, and inference systems. Giving it an apparent advantage when modelling complex conditions. Hybrid frameworks offer fine-grained decision-making and resilient adaptability to real-world …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 1, 2025 · pp. 01–10 Read article