Volume 6, Issue 3 (2019)
Published
Table of contents
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Formulation and Evaluation of Curcumin Microspheres
Abstract: Purpose: To prepare and evaluate curcumin microspheres to improve the absorption and bioavailability of the drug. Methods: Curcumin microspheres were prepared by solvent evaporation method, by using hydroxylpropyl methylcellulose (HPMC), ethyl cellulose (EC), Eudragit S 100 polymer in varying ratios of 1:1, 1:2, 1:3 by using ethanol/dichloromethane as the solvent. The prepared microspheres were evaluated for percentage yield, flow properties, entrapment efficiency, drug content, drug loading, particle size analysis, drug …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 1–11 Read article
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Classical and Contemporary Approach to Uttarbasti: A Review
Abstract: Uttarbasti has been well highlighted in the classics for most of the urogenital disorders in both males and females. Among the disorders being treated with Uttarbasti, infertility stands first. The great ancient acharyas had developed parameters for Ayurvedic procedures and medicines according to their era, so it is the need of the hour to establish the parameters suitable for the modern era without compromising with the principles. In this study, …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 12–21 Read article
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Microneedles: A New Concept for Transdermal Drug Delivery
Abstract: Transdermal delivery keeps a promising carrier in the transport of drugs which get direct access across the skin deep into the systemic circulation. Advantages of transdermal drug delivery system include improved patient compliance, less dose of biologicals, avoidance of gastric irritation as well as the elimination of the first-pass metabolism. Microneedles can be used to improve transdermal drug delivery for some drugs. In this study, we focus on methods of …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 22–29 Read article
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Green Synthesis and Characterization of Silver Nanoparticles by Using Aloe vera Plant Extract
Abstract: Silver nanoparticles (Ag NPs) are important materials that have been studied extensively. Biosynthesis of Ag NPs from plants has an important role in biomedical science and drug discovery application. Green synthesis of Ag NPs is a growing research area because of their potential applications in nanomedicines. Hence, in the present study, we investigated the green synthesis of Ag Nps from silver nitrate using leaves extracts of Aloe vera. The synthesized …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 30–35 Read article
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Targeted Delivery of Nanoparticle Based Taxanes for Breast Cancer Treatment: A Review
Abstract: The most common type of cancers in women is breast cancer. In United States, it is the second common cause of death in women. Metastatic cancer is the advanced stage of breast cancer, which is related to the distribution of cancerous cells from breast tissues to different areas of the body. Over the past numerous years, taxanes are bound to perform a huge role in the management and treatment of …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 36–51 Read article