Volume 6, Issue 2 (2019)
Published
Table of contents
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A Brief Review on Inflammatory Mediators and Drug Therapy for Rheumatoid Arthritis
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease which is characterized by inflammation of the joints and destruction of cartilage and bone. The disease pathology is complex which involves the infiltration and activation of various populations of immune cells along with the release of destructive inflammatory mediators into the synovium of affected joints. Several inflammatory mediators are involved in just like IL-1, IL-6, IL-8, IL-17, IL-18 and tumour necrosis factor-alfa. Treatment …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 1–4 Read article
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Green Synthesis and Characterization of Silver Nanoparticles by Using Albizia Lebbeck (L.) Benth.
Abstract: Development of biologically inspired experimental processes for the synthesis of nanoparticles is evolving into an important branch of nanotechnology. To meet the increasing demands for commercial nanoparticles new eco-friendly “green” methods of synthesis are being discovered. In this study, synthesis of stable silver nanoparticles (Ag NPs) was done using Albizia lebbeck (L.) Benth. leaf extract. UV-Visible spectrometer uses to monitor the reduction of Ag ions and formation of silver nanoparticles …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 11–16 Read article
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Self-Medication Practices in India: a Review Article
Abstract: Self-medication is common in many developing countries. Several factors influence the use of self-medication practices such as educational level, gender, cultural practice, socioeconomic status, and other factors. It is observed form the studies in India that there is a varying prevalence reported by different researchers in different parts of India. Though there is a variance in reported findings among the prevalence these studies findings signal that the self-medication practice among …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 17–20 Read article
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Methods to Overcome High Moisture and Water in Herbs during Tablet Formulation
Abstract: The present study discusses about the role of PVP in converting herbal churna to tablet form. Herbal ingredients are bound to have either high level of moisture and or essential oils and hence making tablets with such herbal ingredients pose variety of challenges such as poor flow property, compressibility, hardness and capping. PVP significantly reduce most of the limitations provided the scientific method of incorporation of the same is adopted. …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 21–24 Read article
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Fabrication and Assessment of Gallic Acid as Novel Drug Carrier
Abstract: Objective: The purpose of the current investigation is to develop and evaluate the polymer-based microspheres to overcome the issues of frequent dosing and high first pass metabolism. Materials and Methods: Gallic acid loaded microsphere were prepared by solvent evaporation technique and the microspheres were evaluated for drug entrapment efficiency, drug loading efficacy, particle size, In-vitro drug release, surface morphology and FTIR spectroscopy studies. Results: The percentage yield, drug entrapment and …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 5–10 Read article