Volume 7, Issue 1 (2020)
Published
Table of contents
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Management of Anal Fissure (Sheqaq al-Maqa’ad) in Unani System of Medicine
Abstract: Fissure is derived from a Latin word “Fissura” which means a groove, natural division, cleft, slit, deep furrow, ulcer or crack like sore. Anal fissure is a longitudinal tear or disruption in the anoderm at the distal end of anal canal. It typically extends from below the dentate line to the anal verge. It affects more than 10% of patients attending proctology clinics and the incidence is growing high day …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 1–4 Read article
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Impact of Clinical Pharmacist in Evaluating Drug–Drug Interactions in Outpatients of a Tertiary Care Hospital: An Observational Study
Abstract: Background: In patients receiving multi-drug therapy, drug–drug interactions (DDIs) are of extensive concern. The term drug–drug interaction is used when the effect of one drug is altered by the concomitant use of another drug. Aim: To analyze the impact of clinical pharmacist in evaluating drug–drug interactions in outpatients of a tertiary care hospital in various departments in a tertiary care hospital. Objectives: To assess the prevalence of drug–drug interactions and …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 10–16 Read article
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RP-HPLC Method for the Simultaneous Estimation of Hydrocodone and Pseudoephedrine in Pharmaceutical Dosage Form
Abstract: A simple, rapid, specific, accurate and precise high-performance liquid chromatographic method was developed for the estimation of Hydrocodone and Pseudoephedrine in pharmaceutical dosage forms. Phenomenex C18 (250×2.2 mm ID) 4.5 µm was the column used. Methanol: Water: TEA (Tri ethyl amine) in the ratio of 50:50:0.5% (v/v/v) was the optimized mobile phase and pH was adjusted to 7.5 by using ortho-phosphoric acid. The flow rate was 1.0 ml/min and effluents …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 17–24 Read article
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Formulation and Development of Iguratimod Film Coated Tablets 25 mg
Abstract: Iguratamide is chemically called as methanesulfonanilid for the treatment of rheumatoid arthritis. The present invention relates to the micron zing technology for insoluble polycrystal medicine Iguratimod, and the micronized Iguratimod has new crystallization and powder direct compression method for formulating tablets. The orally taken quick release preparation with micronized Iguratimod as active component, high efficiency super disintegrants like cross carmellose sodium, surfactants like sodium lauryl sulphate, diluents like MCC PH …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 25–31 Read article
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A Review: Various Adsorbent Carriers used for Enhancing Dissolution Profile
Abstract: In recent times, a large number of studies concerning the improvement of the dissolution rate of poorly water-soluble drugs are focused on the application of various porous materials as the drug carriers. These materials have attracted the attention of researchers owing to their outstanding properties such as large surface area, high pore volumes, microporosity and possibility of surface functionalization. Fujicalin can also be used to assist flow, reduce tablet weight …
Published in Trends in Drug Delivery · Vol. 7, Issue 1, 2020 · pp. 5–9 Read article