Research and Reviews: A Journal of Toxicology
Volume 2, Issue 1 (2012)
Published
Table of contents
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Acetylcholinesterase and Butyrylcholinesterase Activities in Brain and Plasma of Several Species of Birds in India
Abstract: Since timely acquisition of concurrent controls is not always feasible, development of a reference data of normal cholinesterase (ChE) activities for various wildlife species particularly for birds is necessary to diagnose anticholinesterase exposure. In the present study, acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities in brain and plasma of several species of birds collected from Ahmedabad, India, during 2005–2007, were determined. Brain AChE activity ranged from 1.24 µmole/min/g in Indian white-backed …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 1–9 Read article
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Experimental Study on Cyanoacrylate as Wound Adhesive
Abstract: Cyanoacrylates (CAs) have been widely used as surgical glues; however, the high cost of medical CA-based glues limits their use in developing countries. Another possible alternative is the low cost α-CAs which are normally used in commercial glues. The lack of toxicity studies of such agents is considered the main obstacle in their medical application. In the present study, we have evaluated the toxicity profile of commercial glue in comparison …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 10–14 Read article
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Mercury-induced Biochemical Changes in Perna viridis Exposed in Chronic Toxicity Test
Abstract: In the present study, the Asian green mussel, Perna viridis, was exposed to 50, 75, 113, 160 and 253 µg/L Hg concentrations under chronic toxicity for the assessment of biochemical biomarkers. Higher levels of glutathione S-transferase (GST), reduced glutathione (GSH), lipid peroxidation (LPO) and lower levels of protein, catalase (CAT) and acetylcholinesterase (AchE) were found. The values were found to be significant at P < 0.01. This study suggests that …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 15–22 Read article
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The Ames Test in Twenty-first Century
Abstract: Since the 19th century, industrial development has increased exposure to mutagens and possible carcinogens. In order to avoid these health risks, several techniques have been developed to recognize genotoxins. In the 1970s, Dr. Bruce Ames and colleagues, studying the histidine operon of Salmonella typhimurium, observed that histidine (−) auxotroph mutants were reverted to histidine (+) upon exposure to a mutagen. The researchers further observed that known carcinogens were mutagenic to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 23–37 Read article